Anesthesia and critical care (Houston, Tex.)最新文献

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High and Low Dose Ketamine in Post-Traumatic Stress Disorder. 高剂量和低剂量氯胺酮在创伤后应激障碍中的作用。

Anesthesia and critical care (Houston, Tex.) Pub Date : 2025-01-01 Epub Date: 2025-05-05

Joey Day, Devendra K Agrawal

{"title":"High and Low Dose Ketamine in Post-Traumatic Stress Disorder.","authors":"Joey Day, Devendra K Agrawal","doi":"","DOIUrl":"","url":null,"abstract":"Ketamine has unique properties making it a desirable drug to induce general anesthesia during surgery. However, it is typically reserved for children and adolescent patients due to its side effects in adults, including vivid dreams, hallucinations, and confusional states that may be pleasant or distressing. These symptoms may affect patients with post-traumatic stress disorder (PTSD). PTSD is a trauma-related psychological disorder that is mainly characterized by intrusive thoughts, hypervigilance, and re-experiencing of the trauma event. Most of current research focuses on the use of sub-anesthetic doses of ketamine as a treatment for PTSD. Limited information is known about high-dose ketamine use during general anesthesia and the impact this has on patients who suffer from PTSD. A literature review investigating the effects of anesthetic doses of ketamine on PTSD was conducted for this article. Findings suggest that ketamine has dose-related effects on the severity of PTSD. Specifically, low-dose ketamine has the potential as a therapeutic agent in the treatment of PTSD, while high-dose ketamine may cause worsening of PTSD symptoms. This could occur through the increase in psychomimetic symptoms, decrease in plasticity and metaplasticity, and modulation of fear memory systems experienced with anesthetic doses of ketamine. Currently, there are no published research articles directly measuring the effects of high-dose ketamine on PTSD. Further investigation is warranted to understand if anesthetic doses of ketamine worsen PTSD symptoms. This is important because it can help guide the management approach of an anesthesiologist to safely providing anesthesia to PTSD patients.","PeriodicalId":520377,"journal":{"name":"Anesthesia and critical care (Houston, Tex.)","volume":"7 2","pages":"17-25"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12165460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144304331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Racial and Ethnic Disparity in the Administration of General Anesthesia. 全麻给药的种族差异。

Anesthesia and critical care (Houston, Tex.) Pub Date : 2024-01-01 Epub Date: 2024-10-28 DOI: 10.26502/acc.073

Fihr Chaudhary, Devendra K Agrawal

引用次数: 0

Strategies to Minimize Virus Transmission During Anesthesia Procedures in COVID-19 Patients. 减少COVID-19患者麻醉过程中病毒传播的策略

Anesthesia and critical care (Houston, Tex.) Pub Date : 2024-01-01 Epub Date: 2024-10-23 DOI: 10.26502/acc.071

Fihr Chaudhary, Devendra K Agrawal

{"title":"Strategies to Minimize Virus Transmission During Anesthesia Procedures in COVID-19 Patients.","authors":"Fihr Chaudhary, Devendra K Agrawal","doi":"10.26502/acc.071","DOIUrl":"10.26502/acc.071","url":null,"abstract":"Anesthesiologists and the critical care team may be at increased risk of contracting severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2, COVID-19) due to airway manipulations and intubations performed during anesthesia administration and management of patient undergoing surgery. SARS-CoV-2 infections have been reported among healthcare workers. The virus is transmitted by close personal contact and aerosols. During intubation and other procedures involving the airway, the anesthesiologist is especially susceptible to aerosols. We performed a systematic analysis of the published reports on potential effects of COVID-19 during surgery on the anesthesiologist and critical care team. and identified potential immunomodulatory effects of general anesthetics in the presence of COVID-19 infection in patients. The article also provides critical discussion on the current medical management of COVID-19 and highlights the evidence-based key points for a safer practice during anesthesia administration and surgeries both in children and adults, including obstetric procedures and how it could affect pregnant women receiving anesthesia. With regional anesthesia, airway manipulation is not necessary, and healthcare workers and other patients are less likely to contract the same infection.","PeriodicalId":520377,"journal":{"name":"Anesthesia and critical care (Houston, Tex.)","volume":"6 4","pages":"48-59"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11732266/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0