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Meta-Analysis of Acupuncture Therapy for Blood Pressure Reduction in Pre-Elderly with Hypertension 针刺疗法对老年前高血压患者血压降低的meta分析

Indonesian Journal of Medicine Pub Date : 2024-02-16 DOI: 10.26911/theijmed.2024.9.1.727

Danang Aji Prabowo, Hanung Prasetya, Bhisma Murti

{"title":"Meta-Analysis of Acupuncture Therapy for Blood Pressure Reduction in Pre-Elderly with Hypertension","authors":"Danang Aji Prabowo, Hanung Prasetya, Bhisma Murti","doi":"10.26911/theijmed.2024.9.1.727","DOIUrl":"https://doi.org/10.26911/theijmed.2024.9.1.727","url":null,"abstract":"Background: Blood pressure tends to increase with age. Hypertension or high blood pressure often occurs in pre-elderly individuals, who are aged between 45-59 years. Acupuncture is one of the therapies with mild side effects that can reduce blood pressure in pre-elderly individuals. This study aims to evaluate the effectiveness of acupuncture therapy in lowering blood pressure in pre-elderly individuals with hypertension based on similar previous research.Subjects and Methods: This study employed a systematic review and meta-analysis based on PICO framework: Population: Pre-elderly individuals with hypertension. Intervention: Acupunc-ture therapy. Comparison: Non-acupuncture therapy. Outcome: Blood pressure. Data were obtained from the PubMed, MEDLINE, Science Direct, BMC, and Google Scholar databases. The search process utilized keywords such as \"acupuncture\", \"hypertension\", \"Pre elderly\", \"acupunc-ture for hypertension\", AND \"acupuncture for blood pressure\". Article selection was performed using the PRISMA flowchart, and the results were analyzed using Review Manager 5.3 software.Results: A total of 9 articles originating from the United States, Germany, South Korea, China, India, and Taiwan, with a sample size of 492 subjects, indicated that acupuncture therapy for blood pressure reduction in pre-elderly individuals was not significant for systolic blood pressure (SMD= -0.00; 95% CI= -0.81 to 0.81; p=1.00), but it was significant for diastolic blood pressure (SMD= -1.33; 95% CI= -2.60 to -0.05; p= 0.04).Conclusion: Acupuncture therapy for blood pressure reduction in pre-elderly individuals is not significant for systolic blood pressure, but it is significant for diastolic blood pressure. Keywords: acupuncture, hypertension, pre-elderly, blood pressure, meta-analysis","PeriodicalId":518301,"journal":{"name":"Indonesian Journal of Medicine","volume":"9 1","pages":"60-73"},"PeriodicalIF":0.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://theijmed.com/index.php/theijmed/article/download/727/380","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147892979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Meta-Analysis the Effects of Hypertension, High Density Lipoprotein, and Diabetes Mellitus on the Risk of Stroke 高血压、高密度脂蛋白和糖尿病对中风风险影响的 Meta 分析

Indonesian Journal of Medicine Pub Date : 2024-02-01 DOI: 10.26911/theijmed.2023.08.04.10

Najlah Amalia, Vitri Widyaningsih, Burhannudin Ichsan

{"title":"Meta-Analysis the Effects of Hypertension, High Density Lipoprotein, and Diabetes Mellitus on the Risk of Stroke","authors":"Najlah Amalia, Vitri Widyaningsih, Burhannudin Ichsan","doi":"10.26911/theijmed.2023.08.04.10","DOIUrl":"https://doi.org/10.26911/theijmed.2023.08.04.10","url":null,"abstract":"Background: Stroke is defined as an interruption of the blood supply to the brain which is usually caused by a blockage by a blood clot. This causes disruption of the supply of oxygen and nutrients to the brain resulting in damage to brain tissue. This study aims to analyze and estimate the effect of hypertension, high-density lipoprotein, and diabetes mellitus on the risk of stroke.\u0000Subjects and Method: This study is a systematic review and meta-analysis using the PRISMA flow chart and the PICO model. Population: adults. Intervention: hypertension, high-density lipoprotein, and diabetes mellitus. Comparison: normal blood pressure, normal HDL, and normal blood sugar. Outcome: strokes. The databases used were PubMed, Google Scholar, Science Direct, and Proquest with keywords (hypertension OR \"diabetes mellitus\" OR \"high-density lipoprotein\") AND stroke AND (\"cross-sectional\" OR \"case-control\") AND aOR. There were 9 Case-Control studies and 4 Cross-Sectional studies published in 2013-2023 that met the inclusion criteria. Analysis was performed with RevMan 5.3.\u0000Results: 13 studies from Oman, Iran, Lebanon, Ghana, Finland, Nigeria, China, Japan, and Saudi Arabia were selected for meta-analysis. Total sample was 71,037. Had history of hypertension (aOR= 5.48; 95% CI = 2.26 to 13.32; p= 0.002) and diabetes mellitus (aOR = 1.93; 95% CI= 1.45 to 2.57; p< 0.001) increased the risk of stroke. High HDL levels reduced the risk of stroke (aOR = 0.46; 95% CI = 0.27 to 0.79; p= 0.004).\u0000Conclusion: History of hypertension and diabetes mellitus increase the risk of stroke. However, high HDL levels reduce the risk of stroke.\u0000Keywords: hypertension, high-density lipoprotein, diabetes mellitus, stroke.","PeriodicalId":518301,"journal":{"name":"Indonesian Journal of Medicine","volume":"90 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140529044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0