Journal of radiology and clinical imaging最新文献

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Uterine Artery Embolization: A Growing Pillar of Gynecological Intervention. 子宫动脉栓塞：妇科干预的一个日益增长的支柱。

Journal of radiology and clinical imaging Pub Date : 2025-01-01 Epub Date: 2025-02-04 DOI: 10.26502/jrci.2809105

Sunil Balamurugan, Rahul Shah, Kurt Panganiban, Matthew Lehrack, Devendra K Agrawal

{"title":"Uterine Artery Embolization: A Growing Pillar of Gynecological Intervention.","authors":"Sunil Balamurugan, Rahul Shah, Kurt Panganiban, Matthew Lehrack, Devendra K Agrawal","doi":"10.26502/jrci.2809105","DOIUrl":"10.26502/jrci.2809105","url":null,"abstract":"Uterine Artery Embolization (UAE) is a minimally invasive procedure that has emerged as a transformative option for managing uterine leiomyomas (fibroids), postpartum hemorrhage, and other gynecological conditions. While traditional surgical interventions like hysterectomy and myomectomy remain standard, UAE offers a safer alternative for patients seeking uterine preservation or fertility maintenance. This article examines the efficacy, innovations, and challenges of UAE, with a focus on its expanding applications and implications for patient care. Existing research highlights high success rates of UAE, achieving significant symptom relief in over 90% of cases by occluding uterine arterial blood supply with embolic agents to induce localized ischemia and fibroid necrosis. Innovations in embolic materials, such as hydrophobic injectable liquids, and procedural techniques like transradial access have enhanced safety, reduced complications, and improved patient outcomes. The effectiveness of UAE in treating rarer conditions, including uterine arteriovenous malformations and adenomyosis, demonstrates its versatility. However, questions remain about its long-term reproductive impact, especially concerning fertility outcomes and pregnancy rates, as conflicting data suggest potential risks. This critical review addresses these gaps by synthesizing existing studies to assess comparative efficacy of UAE against surgical options, its safety profile, and its role in advancing minimally invasive gynecology. By exploring both well-established and emerging applications, this article underscores the importance of UAE in reducing morbidity, improving quality of life, and preserving reproductive potential. Further research is essential to refine patient selection criteria, optimize techniques, and better understand the long-term outcomes of the procedure, ensuring UAE continues to evolve as a valuable minimally invasive option within modern gynecological care.","PeriodicalId":517438,"journal":{"name":"Journal of radiology and clinical imaging","volume":"8 1","pages":"1-17"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11970953/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reduced Left Ventricular Function on Cardiac MRI in SLE Patients Correlates with Measures of SLE Disease Activity and Inflammation. 系统性红斑狼疮患者心脏核磁共振成像显示的左心室功能减退与系统性红斑狼疮疾病活动性和炎症的测量结果相关。

Journal of radiology and clinical imaging Pub Date : 2023-01-01 Epub Date: 2023-12-29 DOI: 10.26502/jrci.2809088

Audrey M Hagiwara, Erica Montano, Gantseg Tumurkhuu, Moumita Bose, Marianne Bernardo, Daniel S Berman, Galen Cook Wiens, Michael D Nelson, Daniel J Wallace, Janet Wei, Mariko Ishimori, C Noel Bairey Merz, Caroline Jefferies

{"title":"Reduced Left Ventricular Function on Cardiac MRI in SLE Patients Correlates with Measures of SLE Disease Activity and Inflammation.","authors":"Audrey M Hagiwara, Erica Montano, Gantseg Tumurkhuu, Moumita Bose, Marianne Bernardo, Daniel S Berman, Galen Cook Wiens, Michael D Nelson, Daniel J Wallace, Janet Wei, Mariko Ishimori, C Noel Bairey Merz, Caroline Jefferies","doi":"10.26502/jrci.2809088","DOIUrl":"10.26502/jrci.2809088","url":null,"abstract":"Background: Women with SLE have an elevated risk of CVD morbidity and mortality and frequently report chest pain in the absence of obstructive CAD. Echocardiographic studies often demonstrate reduced LV function, correlating with higher disease activity. We used cardiac MRI (cMRI) to investigate the relationship between SLE, related inflammatory biomarkers and cardiac function in female SLE patients.Methods: Women with SLE reporting chest pain with no obstructive CAD (n=13) and reference controls (n=22) were evaluated using stress-rest cMRI to measure LV structure, function, tissue characteristics, and myocardial perfusion reserve index (MPRI). Coronary microvascular dysfunction (CMD) was defined as MPRI <1.84. Serum samples were analyzed for inflammatory markers. Relationships between clinical and cMRI values of SLE subjects were assessed, and groups were compared.Results: 40% of SLE subjects had MPRI < 1.84 on cMRI. Compared to controls, SLE subjects had higher LV volumes and mass and lower LV systolic function. SLICC DI was related to worse cardiac function and higher T1. CRP was related to higher cardiac output and a trend to better systolic function, while ESR and fasting insulin were related to lower LV mass. Lower fasting insulin levels correlated with increased ECV.Conclusions: Among our female SLE cohort, 40% had CMD, and SLICC DI correlated with worse cardiac function and diffuse fibrosis. Higher inflammatory markers and low insulin levels may associate with LV dysfunction. Our findings underline the potential of non-invasive cMRI as a tool for monitoring cardiovascular function in SLE patients.","PeriodicalId":517438,"journal":{"name":"Journal of radiology and clinical imaging","volume":"6 4","pages":"197-207"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10949413/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140178643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0