Bioinspired, Biomimetic and Nanobiomaterials最新文献

Magnetic functionalization of brushite microplatelets and rheological analysis of slurries 刷石微板的磁功能化和泥浆的流变分析

Bioinspired, Biomimetic and Nanobiomaterials Pub Date : 2024-07-18 DOI: 10.1680/jbibn.24.00005

Yashaaswini M., Peifang Dee, H. Le Ferrand

{"title":"Magnetic functionalization of brushite microplatelets and rheological analysis of slurries","authors":"Yashaaswini M., Peifang Dee, H. Le Ferrand","doi":"10.1680/jbibn.24.00005","DOIUrl":"https://doi.org/10.1680/jbibn.24.00005","url":null,"abstract":"Natural ceramics such as bone and teeth possess complex microstructures comprising inorganic minerals oriented in various directions allowing them to perform biological and mechanical functions. Among the various processes developed to mimic natural microstructural arrangement, magnetically assisted slip casting (MASC), a process that locally orients magnetically functionalized ceramic microplatelets suspended in a slurry while the solvent is slowly sucked out, is deemed promising. However, MASC has not yet been applied to bioceramic materials due to the lack of recipe for functionalized bioceramic microplatelets and for slurries. This study therefore explores the magnetic functionalization of synthesized brushite microplatelets with various sizes and their magnetic response. After coating with super paramagnetic iron oxide nanoparticles, the brushite microplatelets synthesized at 2 and 22 °C exhibited a diameter of 10 µm and alignment time of less than 12 s. Aqueous slurries with 12 vol% brushite were prepared and their rheological properties and stabilities were measured. It was found that all slurries exhibited solid-like nature and low stability which may be exacerbated by the presence of the iron oxide at the surface of the brushite. Further approaches to the slurry preparation are discussed to guide future development of calcium phosphate-based slurries in view of future microstructured bioceramics and biocomposites produced using MASC.","PeriodicalId":517191,"journal":{"name":"Bioinspired, Biomimetic and Nanobiomaterials","volume":" 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141825775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Physico-chemical assessments of ion-doped bioactive glasses-based resin infiltrants 离子掺杂生物活性玻璃基树脂浸润剂的物理化学评估

Bioinspired, Biomimetic and Nanobiomaterials Pub Date : 2024-06-11 DOI: 10.1680/jbibn.23.00069

S. Ahmed, A. S. Khan, Asma Tufail Shah, Budi Aslinie Md Sabri, Arumugam Madhan Kumar, Sultan Akhtar, Mukarram Zubair, A. Hakeem, Mohamed Ibrahim Abu Hassan

{"title":"Physico-chemical assessments of ion-doped bioactive glasses-based resin infiltrants","authors":"S. Ahmed, A. S. Khan, Asma Tufail Shah, Budi Aslinie Md Sabri, Arumugam Madhan Kumar, Sultan Akhtar, Mukarram Zubair, A. Hakeem, Mohamed Ibrahim Abu Hassan","doi":"10.1680/jbibn.23.00069","DOIUrl":"https://doi.org/10.1680/jbibn.23.00069","url":null,"abstract":"Bioactive glass-based resin infiltrants were developed to evaluate their chemo-physico-mechanical properties. Three methacrylate-based experimental resin infiltrants were synthesized using 45S5, fluoridated-bioactive glass (F-BG), and boron-bioactive glass (B-BG), whereby pure dimethacrylate resins and ICON® were used as a control infiltrants. The degree of conversion (DC), thermal analysis, and wettability were evaluated. In-vitro bioactivity test(s) and weight measurements were conducted in simulated body fluid for up to 28 days. The optical properties were analyzed in artificial saliva for up to 30 days. The micro-hardness and morphological changes were investigated following chemical aging. The experimental resin infiltrants displayed comparable DC, nearly equivalent wettability to ICON®. An apatite layer was formed on the surface of experimental samples; however, non-linear behavior was observed for weight measurement. Reduction in micro-hardness was observed with chemical aging. The optical properties of experimental infiltrants were better than ICON. The B-BG group showed more resistance to chemical aging and showed less changes during thermal analysis, as well as less loss of hardness. In contrast to other groups, the 45S5-based group showed greater in-vitro bioactivity. F- and B-ions in BGs showed a positive effect and potential to treat white spot lesions within the confines of this inquiry.","PeriodicalId":517191,"journal":{"name":"Bioinspired, Biomimetic and Nanobiomaterials","volume":"31 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141355482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ZnO doped β-TCP ceramic-based scaffold promotes osteogenic and antibacterial activity 掺杂氧化锌的β-TCP 陶瓷基支架促进成骨和抗菌活性

Bioinspired, Biomimetic and Nanobiomaterials Pub Date : 2024-02-12 DOI: 10.1680/jbibn.23.00065

Sangita Mangaraj, Itishree Priyadarshini, S. Swain, T. Rautray

{"title":"ZnO doped β-TCP ceramic-based scaffold promotes osteogenic and antibacterial activity","authors":"Sangita Mangaraj, Itishree Priyadarshini, S. Swain, T. Rautray","doi":"10.1680/jbibn.23.00065","DOIUrl":"https://doi.org/10.1680/jbibn.23.00065","url":null,"abstract":"β-tricalcium phosphate (β-TCP) scaffold, a synthetic bone graft material, has been explored as a potential solution in the healing of bone deformities due to its acceptable degradation rate and ability to support bone growth. However, these scaffolds have limitations such as poor mechanical properties, to stimulate bone growth, and an increased risk of infection after implantation. To overcome these issues, a new type of biomedical scaffold has been developed that incorporated ZnO particles into β-TCP using wet chemical techniques. The scaffolds were created using sintering to produce porous β-TCP scaffolds with good connectivity. The addition of ZnO as a dopant significantly improved the biophysical properties of the scaffolds, with higher concentrations of ZnO leading to better cell adhesion and proliferation. The scaffolds placed in SBF demonstrated their exceptional ability to promote bone growth and regeneration by developing a bone-like apatite layer on their surfaces. The mechanical and physical properties of the scaffolds were effectively assessed using XRD and SEM analyses. To validate the efficacy of the specimen in preventing microbial growth and promoting bone growth, an MTT test, and gene expression investigation were conducted. ZnO-doped β-TCP scaffolds are envisaged to show enormous potential for use in future bone healing applications.","PeriodicalId":517191,"journal":{"name":"Bioinspired, Biomimetic and Nanobiomaterials","volume":"170 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139895213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bactericidal effect of nanosilver synthesized by Neolitsea cassia mucilaginous extract 决明子粘液提取物合成的纳米银的杀菌效果

Bioinspired, Biomimetic and Nanobiomaterials Pub Date : 2024-02-12 DOI: 10.1680/jbibn.22.00010

Sachinthani Rajika Warnasooriya, Asanka Dilup Jayasinghe, Hewa Bandulage Asanthi, Erandi Prasadika Kodithuwakku

{"title":"Bactericidal effect of nanosilver synthesized by Neolitsea cassia mucilaginous extract","authors":"Sachinthani Rajika Warnasooriya, Asanka Dilup Jayasinghe, Hewa Bandulage Asanthi, Erandi Prasadika Kodithuwakku","doi":"10.1680/jbibn.22.00010","DOIUrl":"https://doi.org/10.1680/jbibn.22.00010","url":null,"abstract":"This study focused on green synthesizing silver nanoparticles using mucilaginous leaf extracts of Neolitsea cassia and demonstrating the bactericidal effect of the product against Staphylococcus aureus and Escherichia coli, which are common in polluted water. A concentration series of silver nitrate was subjected to four treatments by mixing with separate [1] aqueous and [2] 80% methanol extracts of N. cassia leaves under [3] atmospheric and [4] nitrogen gaseous environments, for comparison. A linear increment of the dry weight of silver nanoparticles was observed with increasing silver nitrate concentration (r=0.99, p=0) resulting in higher yields from 80% methanol extracts under the atmospheric environment. As characterized by the surface plasmon resonance absorption, energy dispersive X-ray spectra and scanning electron microscopy, quasi-spherical crystalline silver nanoparticles of 11.7 nm average diameter had been synthesized. The disk diffusion method showed that the growth of E. coli and S. aureus in culture media was increasingly inhibited with increasing nanoparticle concentration (r=0.95; p=0, and r=0.93; p=0 respectively). It was concluded that 80% methanol extract under the atmospheric environment was the most productive way to green synthesize silver nanoparticles from the mucilaginous sap of N. cassia.","PeriodicalId":517191,"journal":{"name":"Bioinspired, Biomimetic and Nanobiomaterials","volume":"83 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139894463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0