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Novel Peripherally Selective Cannabinoid Receptor 1 Neutral Antagonist Improves Metabolic Dysfunction-Associated Steatotic Liver Disease in Mice 新型外周选择性大麻素受体 1 中性拮抗剂可改善小鼠代谢功能障碍相关性脂肪肝病症
ACS Pharmacology & Translational Science Pub Date : 2024-08-08 DOI: 10.1021/acsptsci.4c00356
Lucas T. Laudermilk, J. Schlosburg, Elaine A. Gay, Ann M. Decker, Aaron Williams, Rubica Runton, Vineetha Vasukuttan, Archana Kotiya, G. Amato, Rangan Maitra
{"title":"Novel Peripherally Selective Cannabinoid Receptor 1 Neutral Antagonist Improves Metabolic Dysfunction-Associated Steatotic Liver Disease in Mice","authors":"Lucas T. Laudermilk, J. Schlosburg, Elaine A. Gay, Ann M. Decker, Aaron Williams, Rubica Runton, Vineetha Vasukuttan, Archana Kotiya, G. Amato, Rangan Maitra","doi":"10.1021/acsptsci.4c00356","DOIUrl":"https://doi.org/10.1021/acsptsci.4c00356","url":null,"abstract":"","PeriodicalId":517175,"journal":{"name":"ACS Pharmacology & Translational Science","volume":"21 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141925723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Targeting Matrix Metalloproteinase-9 for Therapeutic Intervention in Diabetic Foot Ulcers 靶向基质金属蛋白酶-9 治疗糖尿病足溃疡
ACS Pharmacology & Translational Science Pub Date : 2024-07-16 DOI: 10.1021/acsptsci.4c00263
Mayland Chang
{"title":"Targeting Matrix Metalloproteinase-9 for Therapeutic Intervention in Diabetic Foot Ulcers","authors":"Mayland Chang","doi":"10.1021/acsptsci.4c00263","DOIUrl":"https://doi.org/10.1021/acsptsci.4c00263","url":null,"abstract":"","PeriodicalId":517175,"journal":{"name":"ACS Pharmacology & Translational Science","volume":"92 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141642574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring an Intracellular Allosteric Site of CC-Chemokine Receptor 4 from 3D Models, Probe Simulations, and Mutagenesis 从三维模型、探针模拟和突变中探索 CC-Chemokine Receptor 4 的细胞内异构位点
ACS Pharmacology & Translational Science Pub Date : 2024-07-16 DOI: 10.1021/acsptsci.4c00330
Tianyi Ding, Abdul-Akim Guseinov, Graeme Milligan, Bianca Plouffe, Irina G. Tikhonova
{"title":"Exploring an Intracellular Allosteric Site of CC-Chemokine Receptor 4 from 3D Models, Probe Simulations, and Mutagenesis","authors":"Tianyi Ding, Abdul-Akim Guseinov, Graeme Milligan, Bianca Plouffe, Irina G. Tikhonova","doi":"10.1021/acsptsci.4c00330","DOIUrl":"https://doi.org/10.1021/acsptsci.4c00330","url":null,"abstract":"","PeriodicalId":517175,"journal":{"name":"ACS Pharmacology & Translational Science","volume":"37 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141643628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rapid-Test Kit for Cardiac Troponin I: A Reliable Enzyme-Linked-Immuno-Substrate-Assay-Based Biosensor for Daily-Use Naked-Eye Detection and Pharmacokinetic Studies for Myocardial Infarction in Cardiovascular Disease 心肌肌钙蛋白 I 快速检测试剂盒：基于酶联免疫底物分析的可靠生物传感器，用于心血管疾病中心肌梗死的日用裸眼检测和药代动力学研究
ACS Pharmacology & Translational Science Pub Date : 2024-07-15 DOI: 10.1021/acsptsci.4c00218
Yu-Fang Hsieh, Kuan-Jiuh Lin
{"title":"Rapid-Test Kit for Cardiac Troponin I: A Reliable Enzyme-Linked-Immuno-Substrate-Assay-Based Biosensor for Daily-Use Naked-Eye Detection and Pharmacokinetic Studies for Myocardial Infarction in Cardiovascular Disease","authors":"Yu-Fang Hsieh, Kuan-Jiuh Lin","doi":"10.1021/acsptsci.4c00218","DOIUrl":"https://doi.org/10.1021/acsptsci.4c00218","url":null,"abstract":"","PeriodicalId":517175,"journal":{"name":"ACS Pharmacology & Translational Science","volume":"30 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141648327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A First Insight into the Developability of an Immunoglobulin G3: A Combined Computational and Experimental Approach 首次洞察免疫球蛋白 G3 的可开发性：计算与实验相结合的方法
ACS Pharmacology & Translational Science Pub Date : 2024-07-15 DOI: 10.1021/acsptsci.4c00271
Georgina B. Armstrong, Alan Lewis, Vidhi Shah, Paul Taylor, Craig Jamieson, Glenn A. Burley, William Lewis, Zahra Rattray
{"title":"A First Insight into the Developability of an Immunoglobulin G3: A Combined Computational and Experimental Approach","authors":"Georgina B. Armstrong, Alan Lewis, Vidhi Shah, Paul Taylor, Craig Jamieson, Glenn A. Burley, William Lewis, Zahra Rattray","doi":"10.1021/acsptsci.4c00271","DOIUrl":"https://doi.org/10.1021/acsptsci.4c00271","url":null,"abstract":"","PeriodicalId":517175,"journal":{"name":"ACS Pharmacology & Translational Science","volume":"30 48","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141645682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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