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Effect of Ellagic Acid and Cryptotanshinone on Cell Viability/Cytotoxicity, Metastasis, and Oxidative Stress in Triple-Negative Breast Cancer Cells 鞣花酸和隐丹参酮对三阴性乳腺癌细胞活力/细胞毒性、转移和氧化应激的影响
Experimed Pub Date : 2024-04-24 DOI: 10.26650/experimed.1430845
Ümit Yılmaz, Mehmet Seyhan
{"title":"Effect of Ellagic Acid and Cryptotanshinone on Cell Viability/Cytotoxicity, Metastasis, and Oxidative Stress in Triple-Negative Breast Cancer Cells","authors":"Ümit Yılmaz, Mehmet Seyhan","doi":"10.26650/experimed.1430845","DOIUrl":"https://doi.org/10.26650/experimed.1430845","url":null,"abstract":"","PeriodicalId":514539,"journal":{"name":"Experimed","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140660804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the Effect of Applying Cathodal tDCS to the Left Dorsolateral Prefrontal Cortex on Visual Working Memory 评估在左侧背外侧前额叶皮层应用阴极 tDCS 对视觉工作记忆的影响
Experimed Pub Date : 2024-04-24 DOI: 10.26650/experimed.1393204
Yunus Öksüz, G. Eskikurt
{"title":"Evaluating the Effect of Applying Cathodal tDCS to the Left Dorsolateral Prefrontal Cortex on Visual Working Memory","authors":"Yunus Öksüz, G. Eskikurt","doi":"10.26650/experimed.1393204","DOIUrl":"https://doi.org/10.26650/experimed.1393204","url":null,"abstract":"","PeriodicalId":514539,"journal":{"name":"Experimed","volume":"20 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140664977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of GDF-15 Level in Patients with Membranous Nephropathy 膜性肾病患者体内 GDF-15 水平的影响
Experimed Pub Date : 2024-04-24 DOI: 10.26650/experimed.1403563
Aida Adıkozalova, Sebahat Usta Akgül, E. Demir, Hayriye Şentürk Çiftçi, Fatma Savran Oğuz, Halil Yazıcı, Cigdem Kekik Cinar
{"title":"Effects of GDF-15 Level in Patients with Membranous Nephropathy","authors":"Aida Adıkozalova, Sebahat Usta Akgül, E. Demir, Hayriye Şentürk Çiftçi, Fatma Savran Oğuz, Halil Yazıcı, Cigdem Kekik Cinar","doi":"10.26650/experimed.1403563","DOIUrl":"https://doi.org/10.26650/experimed.1403563","url":null,"abstract":"","PeriodicalId":514539,"journal":{"name":"Experimed","volume":"4 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140665117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing the Impact of Hypercapnic Stimulation on Brain Connectivity Metrics During Functional Magnetic Resonance Imaging 评估功能磁共振成像过程中高碳酸血症刺激对大脑连接性指标的影响
Experimed Pub Date : 2024-04-18 DOI: 10.26650/experimed.1425820
İdiz İset, Ali Bayram
{"title":"Assessing the Impact of Hypercapnic Stimulation on Brain Connectivity Metrics During Functional Magnetic Resonance Imaging","authors":"İdiz İset, Ali Bayram","doi":"10.26650/experimed.1425820","DOIUrl":"https://doi.org/10.26650/experimed.1425820","url":null,"abstract":"","PeriodicalId":514539,"journal":{"name":"Experimed","volume":" 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140690219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of the GnRH Agonist Trigger in Oocyte and Embryo Quality Through Mitochondrial Unfolded Protein Response GnRH 激动剂通过线粒体折叠蛋白反应对卵母细胞和胚胎质量的触发作用
Experimed Pub Date : 2024-03-25 DOI: 10.26650/experimed.1401479
Murat Basar
{"title":"Efficacy of the GnRH Agonist Trigger in Oocyte and Embryo Quality Through Mitochondrial Unfolded Protein Response","authors":"Murat Basar","doi":"10.26650/experimed.1401479","DOIUrl":"https://doi.org/10.26650/experimed.1401479","url":null,"abstract":"","PeriodicalId":514539,"journal":{"name":"Experimed","volume":" 779","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140382715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potential Roles of MicroRNAs in Neurodegenerative Diseases 微小核糖核酸在神经退行性疾病中的潜在作用
Experimed Pub Date : 2024-03-25 DOI: 10.26650/experimed.1395474
Medinenur Yozlu, Duygu GEZEN AK, E. Yücesan
{"title":"Potential Roles of MicroRNAs in Neurodegenerative Diseases","authors":"Medinenur Yozlu, Duygu GEZEN AK, E. Yücesan","doi":"10.26650/experimed.1395474","DOIUrl":"https://doi.org/10.26650/experimed.1395474","url":null,"abstract":"","PeriodicalId":514539,"journal":{"name":"Experimed","volume":" 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140382616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cytogenetic and FISH Examination of 3p Abnormalities in Lung Cancer Patients 肺癌患者 3p 异常的细胞遗传学和 FISH 检查
Experimed Pub Date : 2024-03-25 DOI: 10.26650/experimed.1408284
Narmin Bakhshaliyeva, A. Çırakoğlu, H. Öngen, Esin Bil Tuncay, Yelda Tarkan Argüden
{"title":"Cytogenetic and FISH Examination of 3p Abnormalities in Lung Cancer Patients","authors":"Narmin Bakhshaliyeva, A. Çırakoğlu, H. Öngen, Esin Bil Tuncay, Yelda Tarkan Argüden","doi":"10.26650/experimed.1408284","DOIUrl":"https://doi.org/10.26650/experimed.1408284","url":null,"abstract":"Objective: Deletions or loss of heterozygosity in chromosome 3p are very common in small-cell lung cancer (SCLC) and lung adenocarcinoma (ADC) cases. These are typically found in tumor cells but rarely observed in lymphocytes. This study aimed to evaluate the frequency of 3p deletions and/or abnormalities in the blood of lung cancer patients using conventional cytogenetics and fluorescence in situ hybridization (FISH), by targeting the fragile histidine triad diadenosine triphosphatase (FHIT) gene located at the commonly deleted region of 3p14.2, in lung cancers. Materials and Methods: The study examined 24 SCLC patients, 30 ADC patients, and 20 healthy controls. It used standard procedures to perform a 72-h lymphocyte culture, G-banding, and FISH. Results: All patient group cases showed multiple numerical and structural abnormalities, with numerical abnormalities being more prominent and involving all chromosomes. The following two 3p abnormalities were detected in one patient: del(3)(p22) and t(3;5) (p25;q31). FISH showed positive results regarding FHIT deletion in 9 (30%) ADC, and 7 (29%) SCLC patients. Conclusion: Regardless of the rarity of 3p abnormalities in lymphocytes, a high frequency of chromosomal aberrations may indicate genomic instability. Nevertheless, due to being a time-consuming and expertise-requiring technique, conventional cytogenetics is not recommended for lung cancer monitoring. However, the FISH results suggested that using FISH to examine FHIT gene status in lymphocytes could be a promising biomarker for lung cancer.","PeriodicalId":514539,"journal":{"name":"Experimed","volume":" 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140384383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial Intelligence-Enhanced Application of CRISPR-Cas13a for Cancer Gene Therapy: A Breakthrough Concept 人工智能增强型 CRISPR-Cas13a 在癌症基因治疗中的应用：突破性概念
Experimed Pub Date : 2024-03-25 DOI: 10.26650/experimed.1404013
Tungki Pratama Umar
{"title":"Artificial Intelligence-Enhanced Application of CRISPR-Cas13a for Cancer Gene Therapy: A Breakthrough Concept","authors":"Tungki Pratama Umar","doi":"10.26650/experimed.1404013","DOIUrl":"https://doi.org/10.26650/experimed.1404013","url":null,"abstract":"","PeriodicalId":514539,"journal":{"name":"Experimed","volume":" 44","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140384778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Clinical Sulfonamide Derivative Inhibits B-Raf Protein in Colorectal Cancer and Melanoma Cells. Is It a New Target for Cancer? 一种临床磺酰胺衍生物能抑制结直肠癌和黑色素瘤细胞中的 B-Raf 蛋白。它是癌症的新靶点吗？
Experimed Pub Date : 2024-03-25 DOI: 10.26650/experimed.1378000
Emine Terzi, Beyza Ecem Öz Bedir
{"title":"A Clinical Sulfonamide Derivative Inhibits B-Raf Protein in Colorectal Cancer and Melanoma Cells. Is It a New Target for Cancer?","authors":"Emine Terzi, Beyza Ecem Öz Bedir","doi":"10.26650/experimed.1378000","DOIUrl":"https://doi.org/10.26650/experimed.1378000","url":null,"abstract":"","PeriodicalId":514539,"journal":{"name":"Experimed","volume":" December","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140383327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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