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Cambridge Prisms: Precision Medicine最新文献

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AI Approaches for the Discovery and Validation of Drug Targets 发现和验证药物靶点的人工智能方法
Cambridge Prisms: Precision Medicine Pub Date : 2024-05-24 DOI: 10.1017/pcm.2024.4
A. Wenteler, C.P. Cabrera, W. Wei, V. Neduva, M. Barnes
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引用次数: 0
Ethical Frameworks of Informed Consent in the Age of Pediatric Precision Medicine 儿科精准医疗时代的知情同意伦理框架
Cambridge Prisms: Precision Medicine Pub Date : 2024-05-06 DOI: 10.1017/pcm.2024.3
David Chen
{"title":"Ethical Frameworks of Informed Consent in the Age of Pediatric Precision Medicine","authors":"David Chen","doi":"10.1017/pcm.2024.3","DOIUrl":"https://doi.org/10.1017/pcm.2024.3","url":null,"abstract":"Precision medicine is an emergent medical paradigm that uses information technology to inform the use of targeted therapies and treatments. One of the first steps of precision medicine involves acquiring the patient’s informed consent to protect their rights to autonomous medical decision-making. In pediatrics, there exists mixed recommendations and guidelines of consent-related practices designed to safeguard pediatric patient interests while protecting their autonomy. Here, we provide a high-level, clinical primer of 1) ethical informed consent frameworks widely used in clinical practice and 2) promising modern adaptations to improve informed consent practices in pediatric precision medicine. Given the rapid scientific advances and adoption of precision medicine, we highlight the dual need to both consider the clinical implementation of consent in pediatric precision medicine workflows as well as build rapport with pediatric patients and their substitute decision-makers working alongside interdisciplinary health teams.","PeriodicalId":513802,"journal":{"name":"Cambridge Prisms: Precision Medicine","volume":"6 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141009750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the Epigenetic Landscape: The Role of 5-Hydroxymethylcytosine in Neurodevelopmental Disorders 探索表观遗传景观：5-羟甲基胞嘧啶在神经发育障碍中的作用
Cambridge Prisms: Precision Medicine Pub Date : 2024-04-01 DOI: 10.1017/pcm.2024.2
M. A. S. Khoodoruth, Widaad Nuzhah Chut-kai Khoodoruth, Rafaa AlAlwani
{"title":"Exploring the Epigenetic Landscape: The Role of 5-Hydroxymethylcytosine in Neurodevelopmental Disorders","authors":"M. A. S. Khoodoruth, Widaad Nuzhah Chut-kai Khoodoruth, Rafaa AlAlwani","doi":"10.1017/pcm.2024.2","DOIUrl":"https://doi.org/10.1017/pcm.2024.2","url":null,"abstract":"","PeriodicalId":513802,"journal":{"name":"Cambridge Prisms: Precision Medicine","volume":"441 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140757835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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