Clinical Medicine Research最新文献

Outcome of Emergency Cholecystectomy at Yekatit 12 Hospital Medical College, Addis Ababa, Ethiopia 埃塞俄比亚亚的斯亚贝巴 Yekatit 12 医院医学院急诊胆囊切除术的结果

Clinical Medicine Research Pub Date : 2024-07-23 DOI: 10.11648/j.cmr.20241304.11

Tolera Kebede, Getachew Desta, Alemu Kibret, Wondwossen Amtataw

{"title":"Outcome of Emergency Cholecystectomy at Yekatit 12 Hospital Medical College, Addis Ababa, Ethiopia","authors":"Tolera Kebede, Getachew Desta, Alemu Kibret, Wondwossen Amtataw","doi":"10.11648/j.cmr.20241304.11","DOIUrl":"https://doi.org/10.11648/j.cmr.20241304.11","url":null,"abstract":"Background: Emergency cholecystectomy is the standard treatment for acute cholecystitis worldwide. However, in Ethiopia, it's only performed in a limited number of healthcare facilities, despite its recognition as the preferred treatment by many physicians. To date, there is no study examining the prevalence and outcomes of emergency cholecystectomy in Ethiopia. In our setting, this practice is relatively new, and its outcomes remain unstudied. Purpose: To assess the trends and outcome of emergency cholecystectomy at Yekatit 12 hospital medical college. Method: We employed a longitudinal study design, encompassing all patients who underwent emergency cholecystectomy throughout the study period. Data entry and analysis were conducted using SPSS statistical software version 25. Qualitative variables were depicted in frequencies and percentages, while continuous variables were summarized with mean and standard deviation (SD). Binary logistic regression was applied to evaluate the impact of independent variables on the outcome variable. A significance level of p < 0.05 was taken for statistical significance. Result: Between January 2022 and December 2023, 68 emergency cholecystectomies were performed. Females comprised 60.3% of the cases, with a mean age of 42.43 ± 14.03 years. Surgery for 44.1% of patients occurred between days 4 and 7 after symptom onset, while five patients underwent surgery after 10 days. The mean duration of surgery was 63.9 ± 17.14 minutes. Hospital stays ranged from 2 to 12 days, with a mean of 4.4 ± 2.47 days. Serum creatinine levels exceeding 1 mg/dl (p=0.004) were significantly linked to poor outcomes.","PeriodicalId":513252,"journal":{"name":"Clinical Medicine Research","volume":"139 44","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141810807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Crossed Cerebellar Diaschisis and Cerebral Infarction After Cerebral Hyperperfusion Syndrome Following Carotid Artery Stenting: A Case Report 颈动脉支架置入术后脑过度灌注综合征引起的交叉性小脑扁桃体炎和脑梗塞：病例报告

Clinical Medicine Research Pub Date : 2024-02-21 DOI: 10.11648/j.cmr.20241301.13

Wei-Qin Ning, Si-Qi Chen, Sheng-Peng Diao, Shui-Sheng Zhong

{"title":"Crossed Cerebellar Diaschisis and Cerebral Infarction After Cerebral Hyperperfusion Syndrome Following Carotid Artery Stenting: A Case Report","authors":"Wei-Qin Ning, Si-Qi Chen, Sheng-Peng Diao, Shui-Sheng Zhong","doi":"10.11648/j.cmr.20241301.13","DOIUrl":"https://doi.org/10.11648/j.cmr.20241301.13","url":null,"abstract":"Crossed cerebellar diaschisis (CCD) often occurs after ischemic or hemorrhagic stroke that does great damage to the cortico-ponto-cerebellar pathway (CPCP). Nevertheless, as far as we know, CCD due to cerebral hyperperfusion syndrome (CHS) following carotid artery stenting (CAS) is rare. We report a case where CCD and new cerebral infarction after CHS following CAS was effectively treated by intravenous use of edaravone and mannitol. The patient was a 74-year-old female. She developed dizziness and vomiting accompanied with weakness of the right limb for 8 days and was admitted to our hospital. Computed tomography angiography scan revealed severe stenosis at the beginning of the left internal carotid artery. Further digital subtraction angiography (DSA) revealed severe stenosis at the beginning of the left internal carotid artery, with a stenosis rate of approximately 90%. Therefore, she underwent left CAS implantation. After the operation, the patient developed disturbance of consciousness and decreased muscle strength in the right limb. Intravenous infusion of edaravone and mannitol were then started. After 10 days of medical treatment, the condition of patient improved to mild hemiparesis. The findings in this present case strongly suggest that CHS after CAS for carotid artery stenosis may cause transient CCD.","PeriodicalId":513252,"journal":{"name":"Clinical Medicine Research","volume":"67 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140444686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combining Multiple Tumor Markers to Construct a Clinical Prediction Model for Breast Cancer 结合多种肿瘤标志物构建乳腺癌临床预测模型

Clinical Medicine Research Pub Date : 2024-01-08 DOI: 10.11648/j.cmr.20241301.12

Zebin Liu, Lipeng Lin, Guosheng Zhu, Liying Qiu

引用次数: 0

Therapeutic Effect of Hydroalcoholic Extract for Withania Coagulans for Diuretic Activity in Rodents 薇甘菊水醇提取物对啮齿动物利尿作用的治疗效果

Clinical Medicine Research Pub Date : 2024-01-08 DOI: 10.11648/j.cmr.20241301.11

Rajesh Kumar Sharma, Priyanka Chandolia, Ravi Shankar Sundram, Kumari Isha, Sanjana Soni

引用次数: 0