South Asian Journal of Health Sciences最新文献

{"title":"Mapping the landscape of COVID-19 research from Bangladesh: A bibliometric analysis of highly cited papers","authors":"Raju Vaishya, Brij Mohan Gupta, G. M. Mamdapur, Mallikarjun M. Kappi, K. S. Ali","doi":"10.25259/sajhs_7_2024","DOIUrl":"https://doi.org/10.25259/sajhs_7_2024","url":null,"abstract":"\u0000\u0000We aimed to analyse the highly-cited papers on COVID-19 research from Bangladesh. This study used bibliometric methods to examine the characteristics and trends of COVID-19 research in the country.\u0000\u0000\u0000\u0000To source publication data for the study, the Scopus database was used, until 26th July 2023, employing a specific search strategy. The search yielded 4124 papers, which were then rearranged based on the frequency of citations to obtain the highly cited papers (HCPs), which received 100 or more citations.\u0000\u0000\u0000\u0000The 110 (2.67%) HCPs registered citations ranging from 100 to 1502, with an average of 236.21 Citations per Paper (CPP). Only 30.9% of the publications received external funding and and received an average CPP of 332.0. Similarly, 80% of the HCPs were involved in international collaboration, and and received an average of 249.89 CPP. The major international contributors were the USA, Australia, U.K., and China. The most productive organisations were Jahangirnagar University, International Centre for Diarrhoeal Disease Research, and University Of Dhaka. The most impactful organisations were Neurogen Children’s Healthcare, Bangabandhu Sheikh Mujib Medical University, and Begum Rokeya University. Three most productive authors were Mamun, M.A. (n=8), Saiful Islam, M. (n=6), Tajuddin Sikder, Md. and Bodrud-Doza, Md. (n=4 each).\u0000\u0000\u0000\u0000This study provides the current status of research on COVID-19, including its trends and the most significant contributions from Bangladesh. It has highlighted the top authors, organisations, journals, and research hotspots in the field of COVID-19 research. This information can also help researchers identify potential collaborators, relevant papers, and important research questions in their areas of expertise.\u0000","PeriodicalId":512351,"journal":{"name":"South Asian Journal of Health Sciences","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141920889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Young woman with high fever and a massive rise in N-terminal pro-B-type natriuretic peptide (NT-pro-BNP)","authors":"M. K. Sundarka, A. Sundarka, Krishna Kumar Lohani","doi":"10.25259/sajhs_8_2024","DOIUrl":"https://doi.org/10.25259/sajhs_8_2024","url":null,"abstract":"A 33-year-old lady presented with acute symptoms suggestive of pneumonia. She rapidly deteriorated and needed intensive care unit care. She was found to have an enormous rise in N-terminal pro-B-type natriuretic peptide (NT-Pro-BNP), nearly in six digits without any previous co-morbidity. NT-Pro-BNP high levels could be reflective of cardiac injury, heart failure (HF), or chronic kidney disease (CKD), and a few other medical conditions. The final diagnosis was for acute on chronic kidney disease.","PeriodicalId":512351,"journal":{"name":"South Asian Journal of Health Sciences","volume":"7 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141684961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical profile and risk factors for type-2 diabetes – A cross-sectional study","authors":"P. N. Okoro, Kola Olarinoye, A. Esan","doi":"10.25259/sajhs_2_2023","DOIUrl":"https://doi.org/10.25259/sajhs_2_2023","url":null,"abstract":"\u0000\u0000Type 2 diabetes is a chronic metabolic disorder characterised by elevated blood glucose levels due to insulin resistance or insufficient insulin production. Understanding the prevalence, characteristics, and markers of this disease is essential for effective prevention, management and treatment. The study aims to explore the association between type 2 diabetes and, its prevalence, characteristics and markers.\u0000\u0000\u0000\u0000Adults with type 2 diabetes and matched healthy controls were enrolled in the study. Statistical calculations were used to establish the sample size. Information on demographics, physical examinations and lab tests were collected. We assessed plasma glucose, glycated haemoglobin (HbA1c), serum lipids and serum DPP4.\u0000\u0000\u0000\u0000The mean age (SD) of the population under research was 55.7 (6.12) years for the study subjects and 55.7 (6.11) years for the controls. A positive family history of diabetes was present in 34 (or 33%) of the diabetes patients compared to 11 (or 11%) of the non-diabetic patients (p 0.001). The mean HbA1c in the diabetic group was substantially greater than that of the non-diabetic controls (5.47 1.89%), as expected (7.23 2.69%), p 0.001. It’s interesting to note that total cholesterol was markedly higher in the diabetes participants (5.59 2.24 mmol/L) than in the non-diabetic controls (6.48 1.54 mmol/L), p = 0.001.\u0000\u0000\u0000\u0000Due to common risk factors and underlying mechanisms, type 2 diabetes and hypertension may be related, as suggested by the high prevalence of hypertension in the diabetic group. Type 2 diabetes was substantially related to elevated HbA1c and fasting plasma glucose levels, indicating poor glycaemic control. The higher mean serum Dipeptidyl peptidase-4 (DPP4) level in the group with type 2 diabetes shows a link between high DPP4 levels and the disease, which may have an effect on incretin hormone activity, insulin resistance and therapeutic options. \u0000","PeriodicalId":512351,"journal":{"name":"South Asian Journal of Health Sciences","volume":"17 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141271926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myocardial infarction in non-obstructive coronary artery (MINOCA) in a young girl with multidrug poisoning","authors":"Md Moniruzzaman, Amal Krishna Paul, K M Adnan Bulbul, Md Shariful Islam, Md Nahid Hasan","doi":"10.25259/sajhs_3_2024","DOIUrl":"https://doi.org/10.25259/sajhs_3_2024","url":null,"abstract":"A 24-year-old girl was admitted to the emergency room with chest pain, abdominal discomfort and excessive sleeping tendency after taking some unprescribed medications. She had no risk factors for cardiovascular disease. On query, she gives a history of taking multiple medications available in her room due to some emotional outbreak. Her relatives give a history of taking paracetamol 1000 mg, cephradine 2500 mg, propranolol 100 mg, bilastine 160 mg and hydroxyzine 200 mg. None of these drugs have proven to cause myocardial infarction (MI) at this dosage. Initial ECG showed sinus bradycardia which can be because of taking propranolol. But 2 hours after admission, she developed severe chest pain and at that time ECG showed gross segment (ST) depression. Troponin-i was found to be raised. After initial management, a coronary angiogram was done which revealed normal epicardial coronaries. Patient was managed symptomatically and she recovered completely.","PeriodicalId":512351,"journal":{"name":"South Asian Journal of Health Sciences","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141106653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advocacy for neonates: Will respiratory syncytial virus monoclonal antibodies and maternal vaccine be made available in India?","authors":"Mohamed Muneer Varikkottil, Divya Ajith, Femitha Pournami, Jyothi Prabhakar, Naveen Jain","doi":"10.25259/sajhs_1_2024","DOIUrl":"https://doi.org/10.25259/sajhs_1_2024","url":null,"abstract":"Respiratory syncytial virus (RSV)-related morbidity in children has been widely described. Research has led to the availability of palivizumab for decades in high-income countries. Ongoing research underlines the high priority given to this conundrum. Nirsevimab, a long-acting monoclonal antibody, and a maternal vaccine have been developed and approved for RSV. Neither of these are available in India. Improving the survival of extreme preterm neonates in our country should parallel other strategies to protect them from diseases that affect these high-risk neonates. This case series comprises sick RSV-infected infants from our centre over a single season. Of 187 young infants who presented to the Neonatology Department with features of viral lower respiratory infections, 9 (4.8%) required intensive care. All of them were positive for RSV by nasopharyngeal polymerase chain reaction. A total of 25 (13%) required hospitalisation. Preterm infants presented with apnea or severe respiratory distress. All 9 in the intensive care unit required respiratory support, and 8 needed invasive ventilation. The median duration of hospital stay for these infants was 18 (7–37) days. This report is an appeal to stakeholders towards making these evidence-based prophylactic methods available in India. A preventable problem in high-risk neonates could be reduced. Improving neonatal survival and outcomes calls for our country to be at par with high-income countries for RSV prevention. RSV-related morbidity is an endemic conundrum with a high disease burden. We could take prompt action, akin to efforts taken during the COVID-19 pandemic.","PeriodicalId":512351,"journal":{"name":"South Asian Journal of Health Sciences","volume":"83 S2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141016288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the neuroprotective potential of chrysin on the pre-frontal cortex of adult male Wistar rats","authors":"Ifeanyi Anthony Egwuatu, C. Ozoemena, Fortune Kasiemobi Onuorah","doi":"10.25259/sajhs_15_2023","DOIUrl":"https://doi.org/10.25259/sajhs_15_2023","url":null,"abstract":"\u0000\u0000Excessive free radicals in the human body predispose cells within the various systems to an imbalance and accumulation of oxygen-reactive species, known as oxidative stress. The central nervous system is not spared when it comes to these cell and tissue damages. Oxidative stress on the central nervous system may be responsible for anxiety, spatial memory impairment, neuronal cell depletion, and vacuole-tissue degeneration resulting from neurotoxicity. The use of chemotherapeutic agents such as doxorubicin has been implicated in the build-up of this imbalance between oxygen-reactive species and antioxidants. Therefore, it has become an area of research interest to seek antioxidant supplements that may offer neuroprotective effects. This study is aimed to evaluate the protective potential of chrysin on the pre-frontal cortex of male Wistar rats with doxorubicin-induced cognitive impairment.\u0000\u0000\u0000\u0000Thirty-five adult Wistar rats (180–200 g) were grouped into seven (1–7; n = 5). Group 1, the normal control, received normal saline treatment only throughout the study. Group 2 was administered with doxorubicin only for 21 days by intraperitoneal injection. Groups 3 and 4 were administered with chrysin in low and high doses for 21 days orally. Groups 5, 6 and 7 were exposed to doxorubicin and chrysin for 21 days intra-peritoneally and orally with low, medium and high doses, respectively.\u0000\u0000\u0000\u0000Anti-oxidative biomarkers analysed in Group 2 (doxorubicin-only) demonstrated a significant difference when compared to other groups. This corresponded to significant elevations in apoptotic indicators, inflammatory markers and histological lesions, which were indicative of cognitive impairment. 5, 7-dihydroxyflavone (chrysin) significantly mitigated and also reversed cognitive impairment caused by doxorubicin.\u0000\u0000\u0000\u0000The data showed that chrysin protected against doxorubicin-induced cognitive impairment. This effect is probably made possible by suppressing oxidative stress, inflammation and apoptosis.\u0000","PeriodicalId":512351,"journal":{"name":"South Asian Journal of Health Sciences","volume":" 30","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140213330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lymphangioma circumscriptum – The “Frog Spawn” dermatosis","authors":"V. Vijay, Yogindher Singh","doi":"10.25259/sajhs_29_2023","DOIUrl":"https://doi.org/10.25259/sajhs_29_2023","url":null,"abstract":"","PeriodicalId":512351,"journal":{"name":"South Asian Journal of Health Sciences","volume":" 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140217455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of the gut–brain axis on neurodegenerative diseases and potential benefits of probiotics","authors":"S. Samanta, Saswati Parua Mondal","doi":"10.25259/sajhs_17_2023","DOIUrl":"https://doi.org/10.25259/sajhs_17_2023","url":null,"abstract":"Gut microbiota are an essential community for human health. They produce different bioactive components and short-chain fatty acids for physiological benefits. Intestinal flora elicits an immune response and maintains a balance between inflammatory and anti-inflammatory cytokines during the inflammatory response. The intricate relationship between the activities of gut microbes and brain functions creates the gut–brain axis. Microbial metabolites of the gut reach the brain through blood and lymphatic circulation. The bioactive components from gut microorganisms regulate oxidative stress, cytokine profiles, neuroinflammation, apoptotic reactions and neurodegeneration. Dysbiosis alters the activity of gut microbiota, which causes gastrointestinal disorders, neurodegenerative diseases, metabolic syndrome and cancers. Probiotic bacteria (Lactobacillus spp., Bifidobacterium spp.) have different health promotional effects and exhibit a significant role in immunomodulation. These bacteria display some protective role against various diseases, including neurodegenerative disorders.","PeriodicalId":512351,"journal":{"name":"South Asian Journal of Health Sciences","volume":" 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140217084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}