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Levels of IL-6 and IL-8 in Complicated versus Uncomplicated Urinary Tract Infection 并发症与非并发症尿路感染中 IL-6 和 IL-8 的水平比较

Journal of Chemistry Studies Pub Date : 2024-05-15 DOI: 10.32996/jcs.2024.3.1.3

Maryam Alaa Ahmed, Mohaned Muhsen Ahmed1, Ali Jaleel Ali

{"title":"Levels of IL-6 and IL-8 in Complicated versus Uncomplicated Urinary Tract Infection","authors":"Maryam Alaa Ahmed, Mohaned Muhsen Ahmed1, Ali Jaleel Ali","doi":"10.32996/jcs.2024.3.1.3","DOIUrl":"https://doi.org/10.32996/jcs.2024.3.1.3","url":null,"abstract":"Urinary tract infections (UTIs) are one of the world's most frequent infectious diseases, affecting 150 million people each year and resulting in severe morbidity and high medical expenditures. UTIs can be clinically defined as uncomplicated UTIs (uUTIs) or complicated UTIs (cUTIs) to differentiate infections of benign origin from those with a higher risk of recurrence or progression to severe pathology. The aim of this study was to evaluate interleukin-6 (IL-6) and IL-8 as potential biomarkers in differentiating complicated and uncomplicated. Ninety samples of urine were collected. There were 43 samples from healthy controls and 47 samples from UTI patients—those who have been clinically diagnosed with UTIs by the urologist. The serum IL-6 and IL-8 were measured using an enzyme-linked immunosorbent assay and commercially available kits. The levels of both IL-6 and IL-8 were significantly higher in UTI patient then in control subjects (p=0.001, p=0.001). A significant difference was observed in the mean of level IL-6 between culture positive UTI patients and culture negative UTI patients (p=0.014). In addition, the type of bacterial growth, a significant difference was observed in the mean of serum IL-6 and IL-8 level in UTI caused by gram negative bacteria in comparison with UTI caused by gram positive bacteria. High levels of IL-6 are associated with the growth of gram-negative bacteria, and this indicates that gram-negative bacteria could induce stronger inflammatory responses than gram-positive bacteria. IL-8 levels are higher in UTIs caused by gram-negative bacteria. This result further supported the evidence that gram-negative bacteria are potent inducers of inflammatory responses.","PeriodicalId":512094,"journal":{"name":"Journal of Chemistry Studies","volume":"50 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140972600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carbon Nanotubes as Adsorbents for Heavy Metals: Focus on Arsenic and Hydrargyrum Removal from Water 碳纳米管作为重金属吸附剂：聚焦水中砷和水银的去除

Journal of Chemistry Studies Pub Date : 2024-03-27 DOI: 10.32996/jcs.2024.3.1.2

Uzair Mohammad Kakar, Zh. T. Tauanov, S. Azat, Noor Ahmad Ahmadi, Mohammad Hassan Hassand, Atiqullah Sarwari

{"title":"Carbon Nanotubes as Adsorbents for Heavy Metals: Focus on Arsenic and Hydrargyrum Removal from Water","authors":"Uzair Mohammad Kakar, Zh. T. Tauanov, S. Azat, Noor Ahmad Ahmadi, Mohammad Hassan Hassand, Atiqullah Sarwari","doi":"10.32996/jcs.2024.3.1.2","DOIUrl":"https://doi.org/10.32996/jcs.2024.3.1.2","url":null,"abstract":"Water is the most common and indissoluble substance in the ecosystem. It is really sad that the development of cities, people, and industries has side effects on water resources, as they are getting worse. Heavy metals are mostly found in industries; their toxicity levels are a big challenge. The work details the latest methods employed in the removal of water contaminants with heavy metals, absorption being the technique used. Following the completeness of the literature review for various sorbents that are used to remove heavy metals from wastewater, this article details one of the possible sorbents that can play this role, using carbon nanotubes as a sorbent. Through the test, it has been demonstrated that CNTs have high efficiency, yet some shortcomings have also been shown. It should, additionally, be known that further improvement of desulfurizing agents to make them better at removing heavy metals is needed. This work demonstrates that, in comparison to IL's, which must be supplied by producers, DES's, as an alternative approach, are cheaper, more accessible to use, and much safer for the environment. In other words, the method of adsorption with functionalized CNTs + DESs proved to be the most suitable. The practical diagnostics and conclusions generated from this research should prove valuable to engineers and environmental scientists involved in carbon nanotube applications in environmental remediation.","PeriodicalId":512094,"journal":{"name":"Journal of Chemistry Studies","volume":"77 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140375946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0