Miloš Milošević, Katarina Šarčev, Mirjana Živojinov, Zoran Milošević, Dušan Lalošević, Slobodan Torbica, Maja Ružić
{"title":"Alveolar echinococcosis of the liver with initially suspected intrahepatic cholangiocarcinoma: case report - the significance of preoperative serological diagnostics","authors":"Miloš Milošević, Katarina Šarčev, Mirjana Živojinov, Zoran Milošević, Dušan Lalošević, Slobodan Torbica, Maja Ružić","doi":"10.9738/intsurg-d-24-00008.1","DOIUrl":"https://doi.org/10.9738/intsurg-d-24-00008.1","url":null,"abstract":"\u0000 \u0000 \u0000 Cysts of the liver pose a significant differential-diagnostic problem, considering that the etiology of which can be various. Until recently, alveolar echinococcosis (AE) of the liver in a differential diagnostic analysis of cystic liver lesions with a solid component had little significance in the Vojvodina region. The Syrmia area of Vojvodina is an endemic zone of multilocular echinococcus among wildlife, and the first case of human AE was documented in April 2023. In order to denote the significance of preoperative serological AE diagnostics, we will present a case of AE of the liver initially suspected to be cholangiocarcinoma.\u0000 \u0000 \u0000 \u0000 A patient from the Syrmia area of Vojvodina, reports in November 2023, after the appearance of icterus and epigastric pain. Laboratory results display slightly increased proinflammatory markers, while hepatogram results indicate cholestasis with reactive hepatitis. MRI of the abdomen indicates a focal lesion in the S5/S8 segment of the liver of primarily infiltrative MRI characteristics, which may indicate cholangiocarcinoma. Total body CT scan excludes other lesions. Patient has undergone extended right hepatectomy and the PH results proved the presence of multilocular echinococcus.\u0000 \u0000 \u0000 \u0000 Despite epidemiological risks, diagnosis of infiltrative cystic focal lesions of the liver does not include testing for echinococcus. The reported case indicates the necessity of testing all focal lesions of the liver for AE. The awareness of the epidemiological situation in the region where the patient resides must be raised in order to add serological testing of focal lesions of the liver for multilocular echinococcus to guidelines.\u0000","PeriodicalId":509627,"journal":{"name":"International Surgery","volume":" 33","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141374189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk factors, susceptibility vessel sign and thrombosis pathology for prognosis inpatients with different subtypes of acute ischemic stroke treated with mechanical thrombectomy","authors":"Yingchun Wu, junmei wang, rui sun, Guanqing Feng","doi":"10.9738/intsurg-d-22-00012.1","DOIUrl":"https://doi.org/10.9738/intsurg-d-22-00012.1","url":null,"abstract":"\u0000 \u0000 \u0000 This study highlights the relationship between stroke subtypes, thrombosis pathology, and SVS and identifies probable risk factors affecting recanalization and outcomes in endovascular treatment.\u0000 \u0000 \u0000 \u0000 A prospective study was conducted in which 53 AIS patients received intravenous thrombolysis and mechanical thrombectomy (MT) from January 2017 to December 2019 in a native Hospital. The recanalization was evaluated using modified cerebral infarction thrombolysis grade and prognosis at 3 months using modified rankin Scale (mRS). The risk factors were identified using univariate and multivariate logistic regression analyses. The thrombus samples were stained to determine their composition. Magnetic SWI was used to determine SVS.\u0000 \u0000 \u0000 \u0000 Age, locations of occlusion, and treatments were significantly different of TOAST subtypes (P < 0.05). The time from door to puncture (TDP) and time of operation (TO) were significantly lower in the successful recanalization group (P < 0.05). National Institutes of Health Stroke Scale (NIHSS), MT, TDP, time from onset to recanalization (TOR), and TO have significant differences between the two groups of mRS ≤ 2 and > 3. The occurrence of symptomatic intracranial hemorrhage (sICH) significantly affected the mRS score. The red and mixed thrombi were common in patients with positive SVS whereas the white thrombi were associated with the negative SVS.\u0000 \u0000 \u0000 \u0000 Improved recanalization and prognosis was observed in early MT and when endovascular operations time was reduced.\u0000","PeriodicalId":509627,"journal":{"name":"International Surgery","volume":"57 30","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139960952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mayu Aoki, Takaaki Fujii, C. Honda, Y. Nakazawa, M. Ogino, S. Obayashi, Ken Shirabe
{"title":"Consideration of the process of lymph node metastasis in invasive breast cancer with squamous cell differentiation","authors":"Mayu Aoki, Takaaki Fujii, C. Honda, Y. Nakazawa, M. Ogino, S. Obayashi, Ken Shirabe","doi":"10.9738/intsurg-d-22-00005.1","DOIUrl":"https://doi.org/10.9738/intsurg-d-22-00005.1","url":null,"abstract":"\u0000 \u0000 \u0000 Breast cancer with squamous differentiation is a relatively rare condition. Clinically, lymph node metastasis is uncommon in metaplastic carcinoma We treated a patient with lymph node metastasis of the ductal carcinoma component of invasive ductal carcinoma with squamous cell differentiation.\u0000 \u0000 \u0000 \u0000 An 84-year-old postmenopausal Japanese woman had a left-breast mass with an enlarged lymph node in the left axilla. A biopsy revealed an invasive ductal carcinoma with squamous cell differentiation. A left mastectomy with axillary lymph node dissection was performed. The Histological evaluation revealed invasive ductal carcinoma with squamous cell differentiation. One lymph node was positive for metastasis consisting of ductal carcinoma without squamous cell differentiation.\u0000 \u0000 \u0000 \u0000 This case suggests that lymph node metastasis in ductal carcinoma with squamous differentiation may first involve the ductal carcinoma component and then differentiation may occur in the in volved lymph nodes. This is an interesting case highlighting the process of the progression of lymph node metastasis in cases with breast cancer with squamous cell differentiation.\u0000","PeriodicalId":509627,"journal":{"name":"International Surgery","volume":"164 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140454452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sheng Fan, Xiaolei Zhu, Hui Lin, Junhai Chen, Lintao Li, Sien Shi
{"title":"Comparison of the patient demographics, high resolution computed tomography(HRCT) features of the pulmonary ground-glass opacity(GGO) and its diagnostic value analysis","authors":"Sheng Fan, Xiaolei Zhu, Hui Lin, Junhai Chen, Lintao Li, Sien Shi","doi":"10.9738/intsurg-d-23-00013.1","DOIUrl":"https://doi.org/10.9738/intsurg-d-23-00013.1","url":null,"abstract":"\u0000 Introduction Pulmonary ground-glass opacity (GGO) observed on computed tomography (CT) is widely regarded as a diagnostic feature of lung adenocarcinoma. However, a significant radiological predictive sign remains controversial. In this retrospective study, we conducted a comprehensive analysis of 206 patients with GGO to establish a correlation analysis model between CT images and diagnosis of GGO nodules.Method Histopathologic specimens were obtained from 206 patients. The clinical data, pathologic findings, and thin-section CT features of solid, pure GGO (pGGO), and mixed GGO (mGGO) nodules were compared using rigorous statistical methods, such as t-test, Fisher’s exact test, or univariate logistic regression analysis.Results Significant differences were observed among the three groups in terms of patient demographics, including gender, smoking history, and nodule size. Morphologic CT characteristics, such as the presence of spiculated sign, lobulated sign, vascule sign bubble-lucency sign, or pleural retraction, exhibited significant differences among the solid nodule, pGGO, and mGGO groups. However, no significant differences were observed in terms of air-bronchogram sign. Notably, the incidence of malignancy was significantly higher in pGGO nodules (76.52%) than in solid (48.48%) and mGGO (73.86%) nodules. Patients with mGGO had up to 2.988 times higher hazard of malignant lesions than those with solid nodules (p=0.036). Similarly, the hazard of malignant lesions was 2.941 times higher in patients with pGGO than in those with solid nodules (p=0.007).Conclusion Based on our comprehensive analysis, patients presenting with a mGGO or pGGO on CT scans were more likely to be diagnosed with lung cancer.","PeriodicalId":509627,"journal":{"name":"International Surgery","volume":"13 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139776211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sheng Fan, Xiaolei Zhu, Hui Lin, Junhai Chen, Lintao Li, Sien Shi
{"title":"Comparison of the patient demographics, high resolution computed tomography(HRCT) features of the pulmonary ground-glass opacity(GGO) and its diagnostic value analysis","authors":"Sheng Fan, Xiaolei Zhu, Hui Lin, Junhai Chen, Lintao Li, Sien Shi","doi":"10.9738/intsurg-d-23-00013.1","DOIUrl":"https://doi.org/10.9738/intsurg-d-23-00013.1","url":null,"abstract":"\u0000 Introduction Pulmonary ground-glass opacity (GGO) observed on computed tomography (CT) is widely regarded as a diagnostic feature of lung adenocarcinoma. However, a significant radiological predictive sign remains controversial. In this retrospective study, we conducted a comprehensive analysis of 206 patients with GGO to establish a correlation analysis model between CT images and diagnosis of GGO nodules.Method Histopathologic specimens were obtained from 206 patients. The clinical data, pathologic findings, and thin-section CT features of solid, pure GGO (pGGO), and mixed GGO (mGGO) nodules were compared using rigorous statistical methods, such as t-test, Fisher’s exact test, or univariate logistic regression analysis.Results Significant differences were observed among the three groups in terms of patient demographics, including gender, smoking history, and nodule size. Morphologic CT characteristics, such as the presence of spiculated sign, lobulated sign, vascule sign bubble-lucency sign, or pleural retraction, exhibited significant differences among the solid nodule, pGGO, and mGGO groups. However, no significant differences were observed in terms of air-bronchogram sign. Notably, the incidence of malignancy was significantly higher in pGGO nodules (76.52%) than in solid (48.48%) and mGGO (73.86%) nodules. Patients with mGGO had up to 2.988 times higher hazard of malignant lesions than those with solid nodules (p=0.036). Similarly, the hazard of malignant lesions was 2.941 times higher in patients with pGGO than in those with solid nodules (p=0.007).Conclusion Based on our comprehensive analysis, patients presenting with a mGGO or pGGO on CT scans were more likely to be diagnosed with lung cancer.","PeriodicalId":509627,"journal":{"name":"International Surgery","volume":"184 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139835972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kunihiko Takahashi, Masaya Yokoyama, Junji Kita, Nobuo Hirayama, Kentaro Chochi, Aya Nakagawa, Mayuko Kinoshita, Hiroe Toyoda, M. Furihata, T. Furihata, Keiji Sano, Hisahiro Matsubara
{"title":"Gastric adenocarcinoma with enteroblastic differentiation: Lessons from a rare case","authors":"Kunihiko Takahashi, Masaya Yokoyama, Junji Kita, Nobuo Hirayama, Kentaro Chochi, Aya Nakagawa, Mayuko Kinoshita, Hiroe Toyoda, M. Furihata, T. Furihata, Keiji Sano, Hisahiro Matsubara","doi":"10.9738/intsurg-d-22-00007.1","DOIUrl":"https://doi.org/10.9738/intsurg-d-22-00007.1","url":null,"abstract":"\u0000 \u0000 \u0000 Gastric adenocarcinoma with enteroblastic differentiation (GAED), also known as clear cell carcinoma or fetal gut-like adenocarcinoma is a special type of adenocarcinoma characterized by primitive intestine-like structures. GAED partially overlaps with alfa-fetoprotein (AFP)-producing gastric carcinoma (APGC). There is insufficient information on the biological behavior of GAED, which has a worse prognosis compared to conventional gastric carcinoma (GC).\u0000 \u0000 \u0000 \u0000 We introduce an 82-year-old man who presented 4 years ago with severe epigastralgia; the patient then underwent distal gastrectomy for a large GC. The patient was initially diagnosed with well-to-moderately differentiated gastric adenocarcinoma with lymphatic invasion and without nodal involvement, resulting in a TNM classification of T1N0M0, stage IB. Follow-up computed tomography (CT) 31 months after the gastrectomy revealed a hepatic lesion. Lateral segmentectomy of the liver was performed for therapeutic diagnosis. Pathology specimens from the resected tissue were characterized by glycogen-rich neoplastic cells with eosinophilic cytoplasm with a focal glandular component on hematoxylin-eosin staining and periodic acid-Schiff staining. By retrospective analysis using immunohistochemical staining, Glypican 3 was partially positive and spalt-like transcription factor 4 (SALL-4) was strongly positive in the resected GC and metastatic hepatic carcinoma, indicating that GAED metastasized to the liver.\u0000 \u0000 \u0000 \u0000 Although exceedingly rare, surgeons should recognize GAED as one of the special types of GC. Treatment guidelines for GAED have not yet been established; however, pathological confirmation of GAED when encountering an APGC by immunohistochemical staining for Glypican 3 and SALL-4 is essential to recognize its malignant biological behavior unlike conventional GC.\u0000","PeriodicalId":509627,"journal":{"name":"International Surgery","volume":"9 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139800314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kunihiko Takahashi, Masaya Yokoyama, Junji Kita, Nobuo Hirayama, Kentaro Chochi, Aya Nakagawa, Mayuko Kinoshita, Hiroe Toyoda, M. Furihata, T. Furihata, Keiji Sano, Hisahiro Matsubara
{"title":"Gastric adenocarcinoma with enteroblastic differentiation: Lessons from a rare case","authors":"Kunihiko Takahashi, Masaya Yokoyama, Junji Kita, Nobuo Hirayama, Kentaro Chochi, Aya Nakagawa, Mayuko Kinoshita, Hiroe Toyoda, M. Furihata, T. Furihata, Keiji Sano, Hisahiro Matsubara","doi":"10.9738/intsurg-d-22-00007.1","DOIUrl":"https://doi.org/10.9738/intsurg-d-22-00007.1","url":null,"abstract":"\u0000 \u0000 \u0000 Gastric adenocarcinoma with enteroblastic differentiation (GAED), also known as clear cell carcinoma or fetal gut-like adenocarcinoma is a special type of adenocarcinoma characterized by primitive intestine-like structures. GAED partially overlaps with alfa-fetoprotein (AFP)-producing gastric carcinoma (APGC). There is insufficient information on the biological behavior of GAED, which has a worse prognosis compared to conventional gastric carcinoma (GC).\u0000 \u0000 \u0000 \u0000 We introduce an 82-year-old man who presented 4 years ago with severe epigastralgia; the patient then underwent distal gastrectomy for a large GC. The patient was initially diagnosed with well-to-moderately differentiated gastric adenocarcinoma with lymphatic invasion and without nodal involvement, resulting in a TNM classification of T1N0M0, stage IB. Follow-up computed tomography (CT) 31 months after the gastrectomy revealed a hepatic lesion. Lateral segmentectomy of the liver was performed for therapeutic diagnosis. Pathology specimens from the resected tissue were characterized by glycogen-rich neoplastic cells with eosinophilic cytoplasm with a focal glandular component on hematoxylin-eosin staining and periodic acid-Schiff staining. By retrospective analysis using immunohistochemical staining, Glypican 3 was partially positive and spalt-like transcription factor 4 (SALL-4) was strongly positive in the resected GC and metastatic hepatic carcinoma, indicating that GAED metastasized to the liver.\u0000 \u0000 \u0000 \u0000 Although exceedingly rare, surgeons should recognize GAED as one of the special types of GC. Treatment guidelines for GAED have not yet been established; however, pathological confirmation of GAED when encountering an APGC by immunohistochemical staining for Glypican 3 and SALL-4 is essential to recognize its malignant biological behavior unlike conventional GC.\u0000","PeriodicalId":509627,"journal":{"name":"International Surgery","volume":"461 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139860303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shigeaki Baba, Akira Sasaki, K. Otsuka, A. Umemura, T. Takahara, Y. Akiyama, T. Iwaya, H. Nitta, K. Koeda, Y. Kimura
{"title":"Successfully Completed Laparoscopic Splenectomy for Young Woman With Immune Thrombocytopenic Purpura During Pregnancy in Reduced Port Surgery: A Case Study","authors":"Shigeaki Baba, Akira Sasaki, K. Otsuka, A. Umemura, T. Takahara, Y. Akiyama, T. Iwaya, H. Nitta, K. Koeda, Y. Kimura","doi":"10.9738/intsurg-d-17-00091.1","DOIUrl":"https://doi.org/10.9738/intsurg-d-17-00091.1","url":null,"abstract":"\u0000 \u0000 Immune thrombocytopenic purpura (ITP) during pregnancy is a rare condition; however, it can lead to hemorrhagic complications due to gestational thrombocytopenia during delivery. A splenectomy is the treatment that will result in the highest complete remission rate for ITP and is sometimes required when thrombocytopenia is severe and fails to respond to medical treatment. Herein, we present a case of a patient who underwent a reduced port laparoscopic splenectomy (RPLS) for ITP during pregnancy.\u0000 \u0000 \u0000 \u0000 A 33-year-old female patient, who had past history of miscarriage at the 12th week of gestation and a stillbirth at the 36th week of gestation, was diagnosed with ITP at the 12th week of gestation. The patient received medical treatment, but the platelet count did not increase enough for spontaneous delivery. Therefore, a 3-port RPLS was scheduled at the 20th week of gestation following treatment with high-dose immunoglobulin therapy for 5 days.\u0000 The patient was placed in the right semilateral position. The pneumoperitoneal pressure was set at 8 mmHg, which is lower than that used in a typical operation. The overall procedures were similar to those of a 4-port technique.\u0000 \u0000 \u0000 \u0000 There was no change in the fetal heart rate during or after the operation. The platelet counts increased and were maintained after the RPLS, and the course of the pregnancy was successful. The patient was able to deliver a healthy infant via vaginal delivery at the 37th week of gestation.\u0000 \u0000 \u0000 \u0000 In our experience, RPLS procedures offer high cosmetic satisfaction and are feasible and safe during the second trimester in pregnant women with ITP that does not respond well to medical treatments.\u0000","PeriodicalId":509627,"journal":{"name":"International Surgery","volume":"18 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139539912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Tominaga, Takashi Nonaka, A. Fukuda, Masaaki Moriyama, S. Oyama, Mitsuhisa Ishii, Y. Sumida, H. Takeshita, Makoto Hisanaga, H. Fukuoka, Kazuo Tou, Kenji Tanaka, Terumitsu Sawai, Takeshi Nagayasu
{"title":"Utility of Transanal Tube for Preventing Severe Anastomotic Leakage Following Low Anterior Resection for Patients With Diverting Stoma","authors":"T. Tominaga, Takashi Nonaka, A. Fukuda, Masaaki Moriyama, S. Oyama, Mitsuhisa Ishii, Y. Sumida, H. Takeshita, Makoto Hisanaga, H. Fukuoka, Kazuo Tou, Kenji Tanaka, Terumitsu Sawai, Takeshi Nagayasu","doi":"10.9738/intsurg-d-22-00002.1","DOIUrl":"https://doi.org/10.9738/intsurg-d-22-00002.1","url":null,"abstract":"\u0000 \u0000 The incidence of anastomotic leakage (AL) associated with sphincter-preserving surgery has increased. Diverting stoma (DS) and transanal tube (TT) placement have been reported to reduce the rate of AL. This multicenter study examined the efficacy of TT and DS for preventing AL in rectal cancer patients.\u0000 \u0000 \u0000 \u0000 We reviewed 126 patients who underwent low anterior resection with double-stapling reconstruction between April 2016 and March 2020. Patients were divided into 2 groups according to presence (n = 90) or absence (n = 36) of a TT. Clinicopathologic features were compared between groups.\u0000 \u0000 \u0000 \u0000 Twenty-one patients (16.7%) experienced AL. Frequency of severe AL was significantly lower in the TT group (7.7%) than in the non-TT group (19.4%, P < 0.001). Performance status, operation time, blood loss, and hospital stay were similar between groups. Patients who experienced AL showed significantly longer hospital stays (29 days versus 15 days, P < 0.001). Multivariate analysis revealed placement of a TT as an independent predictor of no AL (odds ratio, 0.306; 95% confidence interval, 0.108–0.870; P = 0.026). Twenty-one patients received both DS construction and TT placement; none of them experienced severe AL.\u0000 \u0000 \u0000 \u0000 The present multicenter study confirmed the efficacy of TT for preventing AL. Transanal tube may have synergistic effects against AL in selected patients with DS.\u0000","PeriodicalId":509627,"journal":{"name":"International Surgery","volume":"18 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139539195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}