Medicine Pub Date : 2024-05-17 DOI: 10.1097/MD.0000000000038197

Qudsia Umaira Khan, Muneeb Ur Rehman, Mohammad Ali Arshad Abbasi, Rubina Rafique Shiekh, Munazza Nazir, S. Raja, Amna Akbar, Sabahat Tasneem, S. K. Jadoon, S. Alvi

{"title":"Correlation between allergic rhinitis or hay fever and lung cancer: A systematic review and meta-analysis","authors":"Qudsia Umaira Khan, Muneeb Ur Rehman, Mohammad Ali Arshad Abbasi, Rubina Rafique Shiekh, Munazza Nazir, S. Raja, Amna Akbar, Sabahat Tasneem, S. K. Jadoon, S. Alvi","doi":"10.1097/MD.0000000000038197","DOIUrl":"https://doi.org/10.1097/MD.0000000000038197","url":null,"abstract":"Background: The association between allergies and cancer is contradictory, whereas some forms of cancer have inverse associations with allergies. Allergic rhinitis (AR) is the most prevalent form of allergy, and lung cancer is one of the most prevalent forms of cancer with the highest mortality rate. Recent studies have reported a positive association between asthma and lung cancer; however, this association is inconclusive. Furthermore, AR is positively associated with asthma; therefore, our research question was to explore whether there is any correlation between AR and lung cancer epidemiologically. Methods: After a rigorous search of PubMed, Google Scholar, and ScienceDirect, 7 eligible articles were included in this systematic review and meta-analysis, including 4724 cases and 9059 controls, 5 from the USA, and one each from Canada and Germany. Results: Pooled analysis (OR, 0.55; 95% CI: 0.45–0.68; P value < .00001) showed a strong inverse relationship between AR and lung cancer. Conclusion: The current meta-analysis suggests an inverse relationship between AR and lung cancer; however, new epidemiological studies are required to observe the current scenario more comprehensively.","PeriodicalId":508590,"journal":{"name":"Medicine","volume":"12 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140962944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The prognostic value of prognostic nutritional index and renal function indicators for mortality prediction in severe COVID-19 elderly patients: A retrospective study 预后营养指数和肾功能指标对重症 COVID-19 老年患者死亡率预测的预后价值：一项回顾性研究

Medicine Pub Date : 2024-05-17 DOI: 10.1097/MD.0000000000038213

Angyang Cao, Wenjun Luo, Long Wang, Jianhua Wang, Yanling Zhou, Changshun Huang, Binbin Zhu

{"title":"The prognostic value of prognostic nutritional index and renal function indicators for mortality prediction in severe COVID-19 elderly patients: A retrospective study","authors":"Angyang Cao, Wenjun Luo, Long Wang, Jianhua Wang, Yanling Zhou, Changshun Huang, Binbin Zhu","doi":"10.1097/MD.0000000000038213","DOIUrl":"https://doi.org/10.1097/MD.0000000000038213","url":null,"abstract":"Identifying prognostic factors in elderly patients with severe coronavirus disease 2019 (COVID-19) is crucial for clinical management. Recent evidence suggests malnutrition and renal dysfunction are associated with poor outcome. This study aimed to develop a prognostic model incorporating prognostic nutritional index (PNI), estimated glomerular filtration rate (eGFR), and other parameters to predict mortality risk. This retrospective analysis included 155 elderly patients with severe COVID-19. Clinical data and outcomes were collected. Logistic regression analyzed independent mortality predictors. A joint predictor “L” incorporating PNI, eGFR, D-dimer, and lactate dehydrogenase (LDH) was developed and internally validated using bootstrapping. Decreased PNI (OR = 1.103, 95% CI: 0.78–1.169), decreased eGFR (OR = 0.964, 95% CI: 0.937–0.992), elevated D-dimer (OR = 1.001, 95% CI: 1.000–1.004), and LDH (OR = 1.005, 95% CI: 1.001–1.008) were independent mortality risk factors (all P < .05). The joint predictor “L” showed good discrimination (area under the curve [AUC] = 0.863) and calibration. The bootstrapped area under the curve was 0.858, confirming model stability. A combination of PNI, eGFR, D-dimer, and LDH provides useful prognostic information to identify elderly patients with severe COVID-19 at highest mortality risk for early intervention. Further external validation is warranted.","PeriodicalId":508590,"journal":{"name":"Medicine","volume":"51 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140965578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gastro-oesophageal reflux disease and hiatus hernia 胃食管反流病和食管裂孔疝

Medicine Pub Date : 2024-02-01 DOI: 10.1016/j.mpmed.2023.12.005

Estefania Moreno, Philip Woodland

引用次数: 0

Coeliac disease 乳糜泻

Medicine Pub Date : 2024-02-01 DOI: 10.1016/j.mpmed.2023.12.003

Jeffrey Butterworth, Louis Los

引用次数: 0

Helicobacter pylori infection and peptic ulcers 幽门螺杆菌感染与消化性溃疡

Medicine Pub Date : 2024-02-01 DOI: 10.1016/j.mpmed.2023.12.006

Debabrata Majumdar, Shi Looi

引用次数: 0

Eosinophilic oesophagitis: practical management and novel therapeutics 嗜酸性粒细胞食管炎：实用管理和新疗法

Medicine Pub Date : 2024-02-01 DOI: 10.1016/j.mpmed.2023.12.011

Radu Rusu, Terry Wong

引用次数: 0

Disorders of the mouth 口腔疾病

Medicine Pub Date : 2024-02-01 DOI: 10.1016/j.mpmed.2023.12.002

S. Nayee, Martyn Ormond, Jeremy D. Sanderson, Michael P. Escudier

引用次数: 0

Accuracy and reproducibility of shear wave elastography according to the size and elasticity of lesions: A phantom study. 根据病变的大小和弹性，剪切波弹性成像的准确性和可重复性:一项幻影研究。

IF 1.6

Medicine Pub Date : 2022-10-14 DOI: 10.1097/MD.0000000000031095

Harim Kim, Haejung Kim, Boo-Kyung Han, Ji Soo Choi, Eun Sook Ko, Eun Young Ko

{"title":"Accuracy and reproducibility of shear wave elastography according to the size and elasticity of lesions: A phantom study.","authors":"Harim Kim, Haejung Kim, Boo-Kyung Han, Ji Soo Choi, Eun Sook Ko, Eun Young Ko","doi":"10.1097/MD.0000000000031095","DOIUrl":"https://doi.org/10.1097/MD.0000000000031095","url":null,"abstract":"While the extrinsic factors affecting reproducibility of shear wave elastography (SWE) have been well documented, there are few resources assessing intrinsic characteristics of the lesion affecting the reproducibility and accuracy of SWE. In this regard, this study aimed to evaluate the accuracy of measured elasticity and the reproducibility of SWE according to the lesion size and stiffness. Two breast radiologists examined 20 targets of 4 different levels of stiffness and 5 different sizes (2.5, 4, 7, 11, and 18 mm) in a customized elasticity phantom. The B-mode image, color elastography image, and kPa measurement were obtained twice by each examiner with a 1-week interval. Inter- and intra-observer reproducibility and the accuracy of measured kPa were analyzed using intraclass correlation coefficient (ICC) and Bland-Altman analysis. Subgroup analysis was run to evaluate the effect of lesion size and stiffness on the reproducibility and accuracy of measured kPa. Inter- and intraobserver reproducibility for measuring kPa showed excellent agreement (ICC: 0.9742 and 0.9582; ICC: 0.9932 and 0.9294). The size and stiffness of the targets did not affect reproducibility. The overall accuracy of measured kPa was very high (ICC: 0.8049). In the subgroup analysis, targets that were ≤4 mm in size showed lower accuracy (ICC: 0.542), whereas targets that were 7 and 11 mm in size showed higher accuracy (ICC: 0.9832 and 0.9656, respectively). SWE shows excellent reproducibility regardless of lesion size or stiffness in phantom targets. The accuracy of measured kPa is high in lesions that are 7 and 11 mm in size but is low in lesions that are ≤4 mm in size.","PeriodicalId":508590,"journal":{"name":"Medicine","volume":" ","pages":"e31095"},"PeriodicalIF":1.6,"publicationDate":"2022-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9575830/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40320958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A comparative study of four Bowie-Dick test under the condition of pressure steam sterilizer simulating gas leakage. 压力蒸汽灭菌器模拟气体泄漏条件下4种鲍伊-迪克试验的对比研究。

IF 1.6

Medicine Pub Date : 2020-12-11 DOI: 10.1097/MD.0000000000023653

Xiaomei Yu, Qing Zhang, Xingling Deng, Jinxiu Liang, Shuqin Hao, Jianling Chen, Heying Du

{"title":"A comparative study of four Bowie-Dick test under the condition of pressure steam sterilizer simulating gas leakage.","authors":"Xiaomei Yu, Qing Zhang, Xingling Deng, Jinxiu Liang, Shuqin Hao, Jianling Chen, Heying Du","doi":"10.1097/MD.0000000000023653","DOIUrl":"https://doi.org/10.1097/MD.0000000000023653","url":null,"abstract":"We aimed to understand the evaluation of different Bowie-Dick test (B-D test) on the performance of pressure steam sterilization equipment in the case of simulated gas leakage, and we selected a pulsating vacuum steam sterilizer to set 4 different gas leakage levels: 1.1, 1.3, 1.5, and 1.7 mbar/min during the B-D test phase. In terms of methods, 4 different brands of B-D test kits (devices) were tested at 4 different leakage rates, and a total of 48 experiments were conducted. The results from univariate analysis revealed that there are statistically significant differences in the judgment of test results among different personnel and brands. The results from multivariate logistic regression analysis displayed that the difference between different personnel was statistically significant (χ = 45.34, P < .001); the difference between different products was statistically significant (χ = 129.37, P < .001); and there was no statistically significant difference between different degree of leakage (χ = 6.99, P > .05). Result judgments of brand 1 and brand 2 are susceptible to subjective factors. The judgment of brand 3 is intuitive and consistent with the evaluation result of brand 4. In conclusion, the order of capacity to evaluate air leakage from best to worst is brand 4→brand 3→brand 1→brand 2.","PeriodicalId":508590,"journal":{"name":"Medicine","volume":" ","pages":"e23653"},"PeriodicalIF":1.6,"publicationDate":"2020-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7738145/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38380030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aerobic, resistance and combined training for adults with chronic kidney disease: A protocol for a systematic review and network meta-analysis. 成人慢性肾脏疾病的有氧、阻力和联合训练:一项系统评价和网络荟萃分析方案

IF 1.6

Medicine Pub Date : 2020-12-04 DOI: 10.1097/MD.0000000000023518

Rong Zeng, Honghao Lai, Zhuoyan Li, Beibei Chen, Lu Wang, Yali Zhang

{"title":"Aerobic, resistance and combined training for adults with chronic kidney disease: A protocol for a systematic review and network meta-analysis.","authors":"Rong Zeng, Honghao Lai, Zhuoyan Li, Beibei Chen, Lu Wang, Yali Zhang","doi":"10.1097/MD.0000000000023518","DOIUrl":"https://doi.org/10.1097/MD.0000000000023518","url":null,"abstract":"Background: Chronic kidney disease (CKD) as a disease that poses a great threat to human health, which has become a public health issue of great concern. Studies have found that exercise training has a positive effect on improving the condition of chronic kidney disease. We will conduct a network meta-analysis to assess the effects of aerobic training, resistance training and combined aerobic and resistance training in treating CKD patients.Methods: We will search PubMed, EMBASE, Medline, Cochrane Central Register of Controlled Trials (CENTRAL), and Web of science to identify randomized control trails (RCTs) that assessed the effect of different exercise training for CKD patients. Cochrane Handbook will be used to evaluate the risk of bias of included articles. We will use Stata or R software to perform data analysis.Results and conclusion: Our systematic review and network meta-analysis will be the first study that investigates the effect of different exercise training for CKD patients, and will provide evidence for management of chronic kidney disease.Ethics and dissemination: The data involved in this study are from published articles. For this reason, there is no need for ethical approval or patient consent.Trial registration: the registration number was: CRD42020157280.","PeriodicalId":508590,"journal":{"name":"Medicine","volume":" ","pages":"e23518"},"PeriodicalIF":1.6,"publicationDate":"2020-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717791/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38683664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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