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Clinical pharmacokinetic characteristics of Jaktinib in subjects with hepatic impairment in a phase I trial I期试验中Jaktinib在肝功能受损受试者中的临床药代动力学特征
Drug Metabolism and Pharmacokinetics Pub Date : 2024-07-01 DOI: 10.1016/j.dmpk.2024.101030
Manna Zhao, Hua Zhang, Sheng Ma, Shuqing Gong, Cheng Wei, Liyan Miao, Weifeng Zhao
{"title":"Clinical pharmacokinetic characteristics of Jaktinib in subjects with hepatic impairment in a phase I trial","authors":"Manna Zhao, Hua Zhang, Sheng Ma, Shuqing Gong, Cheng Wei, Liyan Miao, Weifeng Zhao","doi":"10.1016/j.dmpk.2024.101030","DOIUrl":"https://doi.org/10.1016/j.dmpk.2024.101030","url":null,"abstract":"","PeriodicalId":507827,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141843018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization of plasma vonoprazan and CYP3A activity using its endogenous marker and genetic variants in patients with digestive system disorders 利用消化系统疾病患者的内源性标记物和遗传变异分析血浆中伏诺派赞和 CYP3A 活性的特征
Drug Metabolism and Pharmacokinetics Pub Date : 2024-07-01 DOI: 10.1016/j.dmpk.2024.101027
Kenta Sakaguchi, Takafumi Naito, Kohei Hoshikawa, Yukari Miyadera, Hironari Tanaka, Emi Nakatsugawa, Takahisa Furuta, Ken Sugimoto, J. Kawakami
{"title":"Characterization of plasma vonoprazan and CYP3A activity using its endogenous marker and genetic variants in patients with digestive system disorders","authors":"Kenta Sakaguchi, Takafumi Naito, Kohei Hoshikawa, Yukari Miyadera, Hironari Tanaka, Emi Nakatsugawa, Takahisa Furuta, Ken Sugimoto, J. Kawakami","doi":"10.1016/j.dmpk.2024.101027","DOIUrl":"https://doi.org/10.1016/j.dmpk.2024.101027","url":null,"abstract":"","PeriodicalId":507827,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141707033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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