Paula Banderowicz, Agnieszka Roszyk, Natalia Wierzbowska, Michalina Rodak
{"title":"The effect of isotretinoin therapy on the circulatory system","authors":"Paula Banderowicz, Agnieszka Roszyk, Natalia Wierzbowska, Michalina Rodak","doi":"10.5603/fd.98452","DOIUrl":"https://doi.org/10.5603/fd.98452","url":null,"abstract":"Isotretinoin is a drug belonging to the group of retinoids, which is mainly used in dermatology. Through its mechanism of action, it leads to a reduction in sebum production, which effectively inhibits the formation of acne. Unfortunately, this drug exhibits numerous side effects. This study aimed to review the literature in terms of clinical cases and articles on the side effects of isotretinoin in the context of the cardiovascular system. It has been proven that isotretinoin can harm the circulatory system, causing changes in the structure of the heart walls, thromboembolic episodes, coronary events and lipid metabolism disorders. Further clinical trials are needed to better understand these side effects.","PeriodicalId":507706,"journal":{"name":"Forum Dermatologicum","volume":"93 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140454679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Urszula Maińska, Jakub Żółkiewicz, Wojciech Biernat, Roman Nowicki, M. Sobjanek, M. Sławińska
{"title":"Amelanotic Meyerson’s nevus dermoscopically mimicking amelanotic melanoma","authors":"Urszula Maińska, Jakub Żółkiewicz, Wojciech Biernat, Roman Nowicki, M. Sobjanek, M. Sławińska","doi":"10.5603/fd.98373","DOIUrl":"https://doi.org/10.5603/fd.98373","url":null,"abstract":"","PeriodicalId":507706,"journal":{"name":"Forum Dermatologicum","volume":"28 25","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139782679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Urszula Maińska, Jakub Żółkiewicz, Wojciech Biernat, Roman Nowicki, M. Sobjanek, M. Sławińska
{"title":"Amelanotic Meyerson’s nevus dermoscopically mimicking amelanotic melanoma","authors":"Urszula Maińska, Jakub Żółkiewicz, Wojciech Biernat, Roman Nowicki, M. Sobjanek, M. Sławińska","doi":"10.5603/fd.98373","DOIUrl":"https://doi.org/10.5603/fd.98373","url":null,"abstract":"","PeriodicalId":507706,"journal":{"name":"Forum Dermatologicum","volume":"152 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139842411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A collision tumour of basal cell carcinoma and melanocytic nevus mimicking a melanoma — a case report and review of the literature","authors":"Magdalena Żychowska, Kinga Kołcz, Ewa Kaznowska","doi":"10.5603/fd.98480","DOIUrl":"https://doi.org/10.5603/fd.98480","url":null,"abstract":"","PeriodicalId":507706,"journal":{"name":"Forum Dermatologicum","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140501521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marta Całus, Konrad Bagiński, Małgorzata Duzinkiewicz, Julia Nowowiejska, A. Baran, I. Flisiak
{"title":"Difficulties in the diagnosis of erysipelas in immunosuppressed patients","authors":"Marta Całus, Konrad Bagiński, Małgorzata Duzinkiewicz, Julia Nowowiejska, A. Baran, I. Flisiak","doi":"10.5603/fd.96995","DOIUrl":"https://doi.org/10.5603/fd.96995","url":null,"abstract":"Introduction: Erysipelas is an acute inflammatory condition of the skin and subcutaneous tissue caused by Streptococci . The lesions usually affect the lower limbs or face unilaterally and are characterized by erythema, oedema and pain. By the definition, the disease is accompanied by high fever. On the laboratory investigations, elevated C-reactive protein and leukocytosis are observed. However, in immunocompromised patients, the diagnosis might be unclear. Case description: This study presents cases of three patients admitted to the department of dermatology with erysipelas: a 51-year-old woman with rheumatoid arthritis treated with tocilizumab, methotrexate and methylprednisolone, a 51-year-old woman with systemic lupus erythematosus treated with prednisone, and a 75-year-old woman with rheumatoid arthritis treated with methotrexate. Clinical pictures shared common symptoms in all cases: oedema, erythema and pain in one of the limbs. However, none of the patients had a fever on admission. On laboratory tests, in two cases, there was no significant increase in inflammatory markers. The treatment with intravenous antibiotics and low-molecular heparin resulted in good clinical improvement. Conclusions: Chronic immunosuppressive treatment acting due to inhibition of pro-inflammatory cytokines reduced patients’ immune response, which resulted in the absence of fever and no significant increase in the inflammatory parameters. Presented cases show some peculiarities of erysipelas in the distinct group of immunosuppressed patients and draw attention to unusual manifestations. Nowadays, there are more and more patients treated with biological agents for different diseases, including dermatoses. Hence, the number of atypical erysipelas cases may rise.","PeriodicalId":507706,"journal":{"name":"Forum Dermatologicum","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139233092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}