International Journal of Women's Health最新文献

Exploring the Interplay of Diabetes, Deaf Patient Reported Outcomes, and Cancer Screening in Deaf and Hard of Hearing Women 探索聋人和重听妇女的糖尿病、聋人患者报告结果和癌症筛查之间的相互作用

International Journal of Women's Health Pub Date : 2024-07-01 DOI: 10.2147/ijwh.s461490

Emmanuel Perrodin-Njoku, Sowmya Rao, Regina M. Wang, Christopher Moreland, P. Kushalnagar

引用次数: 0

Atypical Vaginal Aggressive Angiomyxoma in a Virgin: A Case Report from South Jordan 一名处女的非典型阴道侵袭性血管瘤：来自南约旦的病例报告

International Journal of Women's Health Pub Date : 2024-07-01 DOI: 10.2147/ijwh.s465948

Ahlam M Al-Kharabsheh, Bushra AlTarawneh, Seham M Abufraijeh, Omar Abu Azzam

{"title":"Atypical Vaginal Aggressive Angiomyxoma in a Virgin: A Case Report from South Jordan","authors":"Ahlam M Al-Kharabsheh, Bushra AlTarawneh, Seham M Abufraijeh, Omar Abu Azzam","doi":"10.2147/ijwh.s465948","DOIUrl":"https://doi.org/10.2147/ijwh.s465948","url":null,"abstract":": Aggressive angiomyxoma is a locally invasive, rarely diagnosed mesenchymal tumor that predominantly affects the perineal region of women in their reproductive years. It is typically found in areas such as the vagina, vulva, and other pelvic soft tissues, but its presentation can be highly variable. We describe a particularly unique case of aggressive angiomyxoma, presenting in an atypical manner within the vaginal region of a 31-year-old virgin woman. This case is noteworthy for the unusual growth pattern of the angiomyxoma—located strictly within the vaginal epithelium, showing no signs of invasion into surrounding tissues, which is not typical of the aggressive nature of this type of tumor. The patient presented with a mass that protruded through the hymen, an uncommon presentation that led to initial speculation about the nature of the mass. The definitive diagnosis of aggressive angiomyx-oma was made by meticulous histopathological examination after surgical excision of the mass. This case emphasizes the critical importance of considering aggressive angiomyxoma in the differential diagnosis of vaginal masses, particularly those that do not exhibit invasive characteristics. The case also highlights the need for increased awareness among clinicians about the potential for atypical presentations of this rare tumor, to facilitate timely and accurate diagnosis, and to guide appropriate management strategies. This report contributes to the growing body of literature on aggressive angiomyxoma, highlighting the variability in its presentation and the need to heighten suspicion in atypical cases.","PeriodicalId":507655,"journal":{"name":"International Journal of Women's Health","volume":"126 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141843546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

International Journal of Women's Health Pub Date : 2024-07-01 DOI: 10.2147/ijwh.s469513

Nan Tang, Mengyue Pei, Huihui Liu, Jingru Chen, Youting Wang, Lei Xie, Junping Hu, Jing Wang, Yuan Gao

引用次数: 0

Factors Influencing Breast Cancer Awareness in Rural Southwest China: A Cross-Sectional Study 中国西南农村地区乳腺癌认知的影响因素：横断面研究

International Journal of Women's Health Pub Date : 2024-03-01 DOI: 10.2147/ijwh.s453857

Lingling Zhu, Qiang Zhou, Ziyue Huang, Yuan Yang, Ying Yang, Yao Du, Yuqian Zhao, Xiaoping Yu, Tingyuan Li, Wen Chen

引用次数: 0

A Case Report of Meigs’ Syndrome Caused by Ovarian Fibrothecoma with High Levels of CA125 卵巢纤维肉瘤导致梅格斯综合征并伴有高水平 CA125 的病例报告

International Journal of Women's Health Pub Date : 2024-03-01 DOI: 10.2147/ijwh.s450833

Liqin Yuan, Lin Cui, Jie Wang, Li Gong

引用次数: 0

Innovative Surgical Approaches That Improve Individual Outcomes in Advanced Breast Cancer 提高晚期乳腺癌个体疗效的创新手术方法

International Journal of Women's Health Pub Date : 2024-03-01 DOI: 10.2147/IJWH.S447837

Valerii Lutenco, L. Rebegea, Adrian Beznea, George Tocu, Monica Moraru, O. Mihailov, B. Ciuntu, Verginia Luțenco, F. Stănculea, R. Mihailov

{"title":"Innovative Surgical Approaches That Improve Individual Outcomes in Advanced Breast Cancer","authors":"Valerii Lutenco, L. Rebegea, Adrian Beznea, George Tocu, Monica Moraru, O. Mihailov, B. Ciuntu, Verginia Luțenco, F. Stănculea, R. Mihailov","doi":"10.2147/IJWH.S447837","DOIUrl":"https://doi.org/10.2147/IJWH.S447837","url":null,"abstract":"Abstract Breast cancer is the most common cause of cancer death in women and the second cause in the general population. The incidence has increased over time. Women in developing countries often present at an advanced stage where initial surgery is not feasible. Short disease-free intervals, the number of metastatic organs and liver metastasis were consistently associated with poor overall survival. Surgery is an integral part of the therapeutic plan for locally advanced breast cancer. The integration of surgical care into the management of patients with advanced cancer has changed substantially with the use of neoadjuvant chemotherapy. Also, more recently, neoadjuvant endocrine therapy and targeted therapies offer new opportunities to downsize the tumor burden and transform the role of surgery for this population from palliation to largely curative intent. Innovative surgical approach to the primary tumor in metastatic disease may provide survival benefits and local control in some patients. Similar to systemic therapy, surgical therapy for secondary dissemination should be considered in certain cases for improved individual outcomes. Advances in reconstructive techniques have improved the quality of life of these patients.","PeriodicalId":507655,"journal":{"name":"International Journal of Women's Health","volume":"73 4","pages":"555 - 560"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140399411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Performance Evaluation of Noninvasive Prenatal Testing in Screening Chromosome Disorders: A Single-Center Observational Study of 15,304 Consecutive Cases in China 无创产前检测在染色体疾病筛查中的性能评估：对中国 15,304 例连续病例的单中心观察性研究

International Journal of Women's Health Pub Date : 2024-03-01 DOI: 10.2147/IJWH.S455778

Qiang Ye, Guoping Huang, Qin Hu, Qin Man, Xiaoying Hao, Liangyan Liu, Qiang Zhong, Zhao Jin

{"title":"Performance Evaluation of Noninvasive Prenatal Testing in Screening Chromosome Disorders: A Single-Center Observational Study of 15,304 Consecutive Cases in China","authors":"Qiang Ye, Guoping Huang, Qin Hu, Qin Man, Xiaoying Hao, Liangyan Liu, Qiang Zhong, Zhao Jin","doi":"10.2147/IJWH.S455778","DOIUrl":"https://doi.org/10.2147/IJWH.S455778","url":null,"abstract":"Objective This study was to evaluate the performance of noninvasive prenatal testing (NIPT) in detecting fetal chromosome disorders in pregnant women. Methods From October 1st, 2017, to December 31th, 2022, a total of 15,304 plasma cell free DNA-NIPT samples were collected for fetal chromosome disorders screening. The results of NIPT were validated by confirmatory invasive testing or clinical outcome follow-up. Further, NIPT performance between low-risk and high-risk groups, as well as singleton pregnancy and twin pregnancy groups was compared. Besides, analysis of 111 false-positive cases was performed. Results Totally, NIPT was performed on 15,086 eligible venous blood samples, of which 179 (1.19%) showed positive NIPT results and 68 were further validated to be true positive samples via confirmatory invasive testing or follow-up of clinical outcomes. For common chromosome aneuploidies, sex chromosome abnormalities (SCA) and other chromosomal aneuploidies, the detection sensitivities of NIPT were all 100%, the specificities were 99.87%, 99.70%, and 99.68% and the positive predictive values (PPVs) were 65.45%, 31.82%, and 10.91%, respectively. No statistically significant variance in detection performance was observed among 2987 high-risk and 12,099 low-risk subjects, as well as singleton and twin pregnancy subjects. The concentration of cell-free fetal DNA of 111 false-positive cases ranged from 5.5% to 33.7%, which was higher than the minimum requirement of NIPT. Conclusion With stringent protocol, NIPT shows high sensitivity and specificity for detecting fetal chromosome disorders in a large-scale clinical service, helping improving overall pregnancy management.","PeriodicalId":507655,"journal":{"name":"International Journal of Women's Health","volume":"63 1","pages":"563 - 573"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140405153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of COVID-19 on Menstruation and Lower Reproductive Tract Health [Letter] COVID-19 对月经和下生殖道健康的影响 [信］

International Journal of Women's Health Pub Date : 2024-03-01 DOI: 10.2147/ijwh.s470011

Larissa Berry, Sabrina Shahid, Mahdi Sadeghi

引用次数: 0

Case Report: A Rare Case of Primary Angiosarcoma of the Cervix with a Literature Review 病例报告：宫颈原发性血管肉瘤罕见病例及文献综述

International Journal of Women's Health Pub Date : 2024-02-01 DOI: 10.2147/IJWH.S439583

Yuelin Song, Ruizhe Li, Lifei Wang, Hongjing Wang

{"title":"Case Report: A Rare Case of Primary Angiosarcoma of the Cervix with a Literature Review","authors":"Yuelin Song, Ruizhe Li, Lifei Wang, Hongjing Wang","doi":"10.2147/IJWH.S439583","DOIUrl":"https://doi.org/10.2147/IJWH.S439583","url":null,"abstract":"Abstract Primary angiosarcomas are a rare type of soft-tissue sarcomas that originate from endothelial cells. These sarcomas can develop in any part of the body and have a poor prognosis. However, they are commonly found in the skin of elderly white men, particularly on the scalp and head region. Primary angiosarcoma of the cervix is exceptionally rare. To date, only two cases of this disease have been reported worldwide. The diagnosis of the disease is difficult microscopically, requiring immunohistochemistry and genetic testing to distinguish. We report a recent case, in which the lesion was preoperatively considered a high-grade endometrial stromal sarcoma. A 35-year-old woman presented with vaginal bleeding and cervical erosions. A high-grade endometrial stromal sarcoma involving the cervix was considered and a modified radical hysterectomy was performed with bilateral salpingo-oophorectomy and sentinel lymph nodes resection. The gene diagnosis performed by fluorescence in situ hybridization for YWHAE translocation fusion was negative excluding a YWHAE-translocated high-grade endometrial stromal sarcoma. A primary angiosarcoma of the cervix was finally diagnosed. Primary angiosarcoma of the cervix is rare, and gynecologic pathologists do not know it well, so it is easy to be wrongly considered. Immunohistochemistry and genetic testing help confirm the diagnosis.","PeriodicalId":507655,"journal":{"name":"International Journal of Women's Health","volume":"22 12","pages":"265 - 271"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139827714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case Report: A Rare Case of Primary Angiosarcoma of the Cervix with a Literature Review 病例报告：宫颈原发性血管肉瘤罕见病例及文献综述

International Journal of Women's Health Pub Date : 2024-02-01 DOI: 10.2147/IJWH.S439583

Yuelin Song, Ruizhe Li, Lifei Wang, Hongjing Wang

{"title":"Case Report: A Rare Case of Primary Angiosarcoma of the Cervix with a Literature Review","authors":"Yuelin Song, Ruizhe Li, Lifei Wang, Hongjing Wang","doi":"10.2147/IJWH.S439583","DOIUrl":"https://doi.org/10.2147/IJWH.S439583","url":null,"abstract":"Abstract Primary angiosarcomas are a rare type of soft-tissue sarcomas that originate from endothelial cells. These sarcomas can develop in any part of the body and have a poor prognosis. However, they are commonly found in the skin of elderly white men, particularly on the scalp and head region. Primary angiosarcoma of the cervix is exceptionally rare. To date, only two cases of this disease have been reported worldwide. The diagnosis of the disease is difficult microscopically, requiring immunohistochemistry and genetic testing to distinguish. We report a recent case, in which the lesion was preoperatively considered a high-grade endometrial stromal sarcoma. A 35-year-old woman presented with vaginal bleeding and cervical erosions. A high-grade endometrial stromal sarcoma involving the cervix was considered and a modified radical hysterectomy was performed with bilateral salpingo-oophorectomy and sentinel lymph nodes resection. The gene diagnosis performed by fluorescence in situ hybridization for YWHAE translocation fusion was negative excluding a YWHAE-translocated high-grade endometrial stromal sarcoma. A primary angiosarcoma of the cervix was finally diagnosed. Primary angiosarcoma of the cervix is rare, and gynecologic pathologists do not know it well, so it is easy to be wrongly considered. Immunohistochemistry and genetic testing help confirm the diagnosis.","PeriodicalId":507655,"journal":{"name":"International Journal of Women's Health","volume":"6 11","pages":"265 - 271"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139887481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0