The Lancet Regional Health - Western Pacific最新文献

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Use of the Chinese version of the MATRICS Consensus Cognitive Battery to assess cognitive functioning in individuals with high risk for psychosis, first-episode schizophrenia and chronic schizophrenia: a systematic review and meta-analysis 使用 MATRICS 共识认知测验中文版评估精神病高危人群、首发精神分裂症患者和慢性精神分裂症患者的认知功能:系统综述和荟萃分析
The Lancet Regional Health - Western Pacific Pub Date : 2024-02-01 DOI: 10.1016/j.lanwpc.2024.101016
Bing Cai, Yikang Zhu, Dongyang Liu, Yaxi Li, Marlys Bueber, Xuezhi Yang, Guoshuai Luo, Ying Su, Margaux M. Grivel, Lawrence H. Yang, Min Qian, William S. Stone, Michael R. Phillips
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引用次数: 0
Protective effect of previous infection and vaccination against reinfection with BA.5 Omicron subvariant: a nationwide population-based study in Japan 既往感染和接种疫苗对再次感染 BA.5 Omicron 亚变异体的保护作用:日本全国人口研究
The Lancet Regional Health - Western Pacific Pub Date : 2023-09-01 DOI: 10.2139/ssrn.4463500
Noriko Kitamura, Kanako Otani, Ryo Kinoshita, Fangyu Yan, Yu Takizawa, Kohei Fukushima, Daisuke Yoneoka, Motoi Suzuki, T. Kamigaki
{"title":"Protective effect of previous infection and vaccination against reinfection with BA.5 Omicron subvariant: a nationwide population-based study in Japan","authors":"Noriko Kitamura, Kanako Otani, Ryo Kinoshita, Fangyu Yan, Yu Takizawa, Kohei Fukushima, Daisuke Yoneoka, Motoi Suzuki, T. Kamigaki","doi":"10.2139/ssrn.4463500","DOIUrl":"https://doi.org/10.2139/ssrn.4463500","url":null,"abstract":"Background: The Omicron variant of SARS-CoV-2 was reported to evade immunity derived from vaccination and previous infection. A better understanding of hybrid immunity informs effective infection control strategies. Since the reinfection risk was not well-assessed in East Asia, this study aims to evaluate the risk of infection with Omicron subvariant BA.5 among previously infected individuals in Japan.Methods: All notified cases were extracted from the Japanese national COVID-19 surveillance database including 20,297,335 records up to 25 September 2022. Reinfection with BA.5 was defined as the second infection notified during the BA.5 dominated period. The protective effect of prior infections against reinfections with BA.5 was estimated by applying a case-population design and the protective effect of vaccination was estimated by a multivariable Cox regression adjusting for age, sex, variants of prior infection, and the time since the last vaccination.Findings: Among 19,830,548 SARS-CoV-2 infections, 233,424 (1·2%) were reinfected with BA.5. The protective effect of prior infection with Wuhan, Alpha, Delta, and BA.1/BA.2 against BA.5 reinfection was 46·2% (45·5–47·0), 35·2% (34·2–36·2), 40·6% (39·9–41·2), and 73·9% (73·4–74·4), respectively. The risk of BA.5 reinfection was reduced by 14%, 41%, and 71% by two, three and four doses of vaccination, respectively, compared with one-dose vaccination.Interpretation: The prior infections with Omicron subvariant BA.1/BA.2 protected BA.5 reinfection more than pre-Omicron variants. Increased frequency of vaccination led to more protection from reinfection with BA.5. Up-to-date vaccination may be encouraged to prevent future reinfection among the previously infected population.Funding: RK received funding from the Japan Society for the Promotion of Science (JSPS) KAKENHI (21K17307). MS and TK received the Ministry of Health Labour and Welfare Science Research Grant (23HA2005).Declaration of Interest: The authors declare that they have no conflict of interest.Ethical Approval: No ethical approval was required because this study was conducted for public health purposes using national surveillance data.","PeriodicalId":507478,"journal":{"name":"The Lancet Regional Health - Western Pacific","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139346114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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