Comprehensive Psychoneuroendocrinology最新文献

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Coronavirus Disease 2019 and its Impact on the Cognition of Older Adults: Unraveling the Role of Inflammation 2019年冠状病毒疾病及其对老年人认知能力的影响:揭示炎症的作用
Comprehensive Psychoneuroendocrinology Pub Date : 2024-05-01 DOI: 10.21203/rs.3.rs-3904203/v1
Shahrzad Mortazavi, Vahid Rashedi, Bahman Cheraghian, Fatemeh Pourshams, Saeid Saeidimehr, Bahram Dehghan, Maryam Pourshams
{"title":"Coronavirus Disease 2019 and its Impact on the Cognition of Older Adults: Unraveling the Role of Inflammation","authors":"Shahrzad Mortazavi, Vahid Rashedi, Bahman Cheraghian, Fatemeh Pourshams, Saeid Saeidimehr, Bahram Dehghan, Maryam Pourshams","doi":"10.21203/rs.3.rs-3904203/v1","DOIUrl":"https://doi.org/10.21203/rs.3.rs-3904203/v1","url":null,"abstract":"Background: The Coronavirus Disease 2019 (COVID-19) pandemic has had a significant global impact, particularly on the older adult population. To address concerns regarding the emergence and persistence of cognitive impairment and its potential risk factors, this study aimed to investigate cognitive function and its relationship with inflammation in older COVID-19 survivors during a three-month follow-up. Methods: In this descriptive-analytical study, 177 hospitalized patients with COVID-19 aged >60 years were examined between July 2021 and February 2022.Psychiatric and cognitive assessments were conducted at discharge and at one month and three months post-discharge. All the statistical analyses were conducted using a Statistical Package for the Social Sciences (SPSS) version 24 (P<0.05). Cognitive status was analyzed with the Repeated Measures Test, and relationships between inflammatory indices and cognitive function were explored via the Pearson correlation test and Mann‒Whitney U test. The normality of the data was examined using the Kolmogorov‒Smirnov test. Results:A cognitive assessment of patients indicated lower scores onthe informant subscales of the General Practitioner Assessment of Cognition (GPCOG) during the time of discharge, as well as at the 1-and 3-month follow-up intervals. Negative correlations were found between cognitive function and depression/anxiety. Elevated C-reactive protein (CRP), D-dimer, and Lactate dehydrogenase (LDH) levels were linked to lower cognitive scores, while the Erythrocyte sedimentation rate (ESR) and Creatine phosphokinase (CPK) were not significantly correlated. Over time, cognitive function and anxiety improved, while depression and daily activity challenges persisted. Conclusions: This study highlights the lingering impact of inflammation on cognition among older COVID-19 survivors. Moreover, these findings underscore the urgent need for focused interventions and rehabilitation efforts to foster sustained cognitive recovery in this population.","PeriodicalId":506465,"journal":{"name":"Comprehensive Psychoneuroendocrinology","volume":"13 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141033508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in hair cortisol in a New Zealand community sample during the Covid-19 pandemic Covid-19 大流行期间新西兰社区样本毛发皮质醇的变化
Comprehensive Psychoneuroendocrinology Pub Date : 2024-02-01 DOI: 10.1016/j.cpnec.2024.100228
E. Broadbent, Urs Nater, Nadine Skoluda, N. Gasteiger, Ru Jia, T. Chalder, Mikaela Law, Kavita Vedhara
{"title":"Changes in hair cortisol in a New Zealand community sample during the Covid-19 pandemic","authors":"E. Broadbent, Urs Nater, Nadine Skoluda, N. Gasteiger, Ru Jia, T. Chalder, Mikaela Law, Kavita Vedhara","doi":"10.1016/j.cpnec.2024.100228","DOIUrl":"https://doi.org/10.1016/j.cpnec.2024.100228","url":null,"abstract":"","PeriodicalId":506465,"journal":{"name":"Comprehensive Psychoneuroendocrinology","volume":"1109 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139820417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preliminary results of anti-inflammatory cytokine concentrations predicting therapy outcome in panic disorder 预测惊恐障碍治疗效果的抗炎细胞因子浓度的初步结果
Comprehensive Psychoneuroendocrinology Pub Date : 2024-02-01 DOI: 10.1016/j.cpnec.2024.100227
Vanessa Renner, R. Conrad, Clemens Kirschbaum, Thomas Lorenz, K. Petrowski
{"title":"Preliminary results of anti-inflammatory cytokine concentrations predicting therapy outcome in panic disorder","authors":"Vanessa Renner, R. Conrad, Clemens Kirschbaum, Thomas Lorenz, K. Petrowski","doi":"10.1016/j.cpnec.2024.100227","DOIUrl":"https://doi.org/10.1016/j.cpnec.2024.100227","url":null,"abstract":"","PeriodicalId":506465,"journal":{"name":"Comprehensive Psychoneuroendocrinology","volume":"10 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139871921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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