Journal of Applied Veterinary Sciences最新文献

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Potentiating the Epidural Analgesic Effect of Lidocaine in Uda Sheep with Xylazine and Medetomidine 用赛拉嗪和美托咪定增强乌达绵羊硬膜外利多卡因的镇痛效果

Journal of Applied Veterinary Sciences Pub Date : 2024-04-01 DOI: 10.21608/javs.2024.275091.1323

Shittu Shamsudeen, Sherifat Idris, Adamu Abubakar, Mayaki Abubakar

{"title":"Potentiating the Epidural Analgesic Effect of Lidocaine in Uda Sheep with Xylazine and Medetomidine","authors":"Shittu Shamsudeen, Sherifat Idris, Adamu Abubakar, Mayaki Abubakar","doi":"10.21608/javs.2024.275091.1323","DOIUrl":"https://doi.org/10.21608/javs.2024.275091.1323","url":null,"abstract":"This study was undertaken to compare the analgesic effects of lidocaine, xylazine, and medetomidine alone and their combinations with lidocaine in Uda sheep. The sheep (n = 6) were assigned to five different epidural treatment groups using a cross-over design with a wash-out period of one week between the treatment groups. The group (A) received lidocaine at 2.86 mg/kg, the group (B) received xylazine at 0.05 mg/kg, the group (C) received medetomidine at 20 µg/kg, the group (D) received lidocaine-xylazine combination at 2.15 mg/kg and 0.125 mg/kg, respectively, and the group (E) received lidocaine-medetomidine combination at 2.15 mg/kg and 5 µg/kg, respectively. The analgesic effect was evaluated by the needle-prick test method. The onset and duration of analgesia in the mentioned regions were recorded. Ataxic and sedative effects were carefully observed and recorded according to the scoring system. Blood was collected at baseline (0), immediately after onset, and 24 hours post-administration. Results showed that medetomidine treatment produced a highly significant (p < 0.01) earlier onset of action (6–8 min) than the rest of the treatment groups. Medetomidine treatment also produced a significantly (p < 0.001) longer duration of analgesia (190-230 min) than the rest of the treatment groups. Lidocaine alone or in combination with xylazine or medetomidine induced severe ataxia, while xylazine and medetomidine alone or in combination with lidocaine produced mild to moderate sedation. In conclusion, epidural administration of medetomidine, lidocaine-xylazine, and xylazine produced a prolonged, longer duration of analgesia with useful systemic sedation in sheep.","PeriodicalId":505954,"journal":{"name":"Journal of Applied Veterinary Sciences","volume":"14 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140764190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anatomical and Ultrastructural Studies on the Dromedary Camel Cecum 单峰驼盲肠的解剖学和超微结构研究

Journal of Applied Veterinary Sciences Pub Date : 2024-04-01 DOI: 10.21608/javs.2024.270202.1318

El-Khatib A.M.A, Ali A.M., Taha A.A.M., Elhassan M.O., Ibrahim Z.H., Alshanbari F.A., Althnaian A.

{"title":"Anatomical and Ultrastructural Studies on the Dromedary Camel Cecum","authors":"El-Khatib A.M.A, Ali A.M., Taha A.A.M., Elhassan M.O., Ibrahim Z.H., Alshanbari F.A., Althnaian A.","doi":"10.21608/javs.2024.270202.1318","DOIUrl":"https://doi.org/10.21608/javs.2024.270202.1318","url":null,"abstract":"The main functions of the mammalian cecum include microbial digestion of soluble and insoluble carbohydrates and the absorption of significant amounts of water and electrolytes. The present study was carried out to investigate the gross anatomy and electron microscopy of the cecum in adult camels ( Camelus dromedarius), which still needs to be clarified. The study was conducted using samples collected from camels slaughtered at an abattoir in Omdurman, Sudan. The camel cecum, which occupied the right part of the abdomen, was situated caudally to the abomasum and directed caudally to the pelvis. It was short and S-shaped and began largely at the ceco-colic junction at the level of the fifth lumbar vertebra and became smaller towards its apex. Morphometrically, camel cecum constituted 3.2% of the large intestine length, 1% of both the small intestine and large intestine length, and 0.10% of the long axis of the animal body. Ultra-structurally, the cecal mucosa showed several folds and was lined by a simple columnar epithelium with many intestinal cells (enterocytes) and goblet cells; two types of enterocytes were shown: type one contained a dark cytoplasm and type two had a light cytoplasm. In conclusion, the cecum in dromedary camels was generally similar in structure to other domestic animals; however, they have a shorter cecum compared to ruminants.","PeriodicalId":505954,"journal":{"name":"Journal of Applied Veterinary Sciences","volume":"61 33","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140795358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0