{"title":"XXXI RUSSIAN NATIONAL CONGRESS \"MAN AND MEDICINE\". APRIL 15-18, 2024. Collection of abstracts","authors":"A. Editorial","doi":"10.15829/1728-8800-2024-6s","DOIUrl":"https://doi.org/10.15829/1728-8800-2024-6s","url":null,"abstract":"<jats:p>.</jats:p>","PeriodicalId":504164,"journal":{"name":"Cardiovascular Therapy and Prevention","volume":"26 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140656106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Expert opinion on the article \"Association between cardiovascular mortality and deprivation in the adult population of Russia\"","authors":"V. Perkhov","doi":"10.15829/1728-8800-2024-3979","DOIUrl":"https://doi.org/10.15829/1728-8800-2024-3979","url":null,"abstract":"Экспертная оценка статьи \"Ассоциация между смертностью от болезней системы кровообращения и депривацией у взрослого населения России\" была выполнена на предмет её соответствия общим критериям качества научных исследований, таких как актуальность для здравоохранения, правильность выбора и использования статистических методов, достоверность и научно-практическая ценность результатов исследования, и отражает исключительно личную позицию рецензента.","PeriodicalId":504164,"journal":{"name":"Cardiovascular Therapy and Prevention","volume":"38 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140707508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. V. Blagova, V. A. Bryukhanov, M. B. Kislova, V. A. Yumasheva, M. S. Gaeva, D. Ainetdinova, N. Gagarina, E. A. Kogan
{"title":"Post-COVID-19 myocardium and coronary involvement in a young patient: differential diagnosis and comprehensive treatment","authors":"O. V. Blagova, V. A. Bryukhanov, M. B. Kislova, V. A. Yumasheva, M. S. Gaeva, D. Ainetdinova, N. Gagarina, E. A. Kogan","doi":"10.15829/1728-8800-2024-3923","DOIUrl":"https://doi.org/10.15829/1728-8800-2024-3923","url":null,"abstract":"The state of the heart after a coronavirus disease 2019 (COVID-19, coronavirus disease 2019) is very diverse and in some cases requires a complex differential diagnosis. We described a 35-year-old smoking male patient who, by the end of the first month after COVID-19, developed left ventricular dysfunction with decrease in ejection fraction to 25-30% and persistent left bundle branch block (LBBB). Echocardiography also detected local contractility disorders. A significant increase in blood anticardiac antibody titers was noted. Myocardial biopsy revealed active lymphocytic myocarditis, coronavirus ribonucleic acid, while coronary angiography revealed extensive stenosis of the anterior interventricular artery. On the first day after balloon angioplasty and stenting, the disappearance of LBBB block was noted with the appearance of deep negative T waves in the precordial leads, which did not allow ruling out a previous myocardial infarction. As a result of treatment of heart failure and steroid therapy, the structural and functional cardiac parameters and the electrocardiography were completely normalized by the end of the second year of treatment. Only a transient LBBB remained at high loads. Cardiac computed tomography after 2 years showed no delayed contrast agent accumulation in the myocardium, and coronary stenosis up to 30%.The mechanisms of complex myocardial and coronary damage (including the role of coronaritis in the atherosclerosis progression) after COVID-19 are discussed.","PeriodicalId":504164,"journal":{"name":"Cardiovascular Therapy and Prevention","volume":"107 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140707200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Dzhioeva, Y. S. Timofeev, V. A. Metelskaya, A. A. Bogdanova, T. Y. Vedenikin, O. Drapkina
{"title":"Role of epicardial adipose tissue in the pathogenesis of chronic inflammation in heart failure with preserved ejection fraction","authors":"O. Dzhioeva, Y. S. Timofeev, V. A. Metelskaya, A. A. Bogdanova, T. Y. Vedenikin, O. Drapkina","doi":"10.15829/1728-8800-2024-3928","DOIUrl":"https://doi.org/10.15829/1728-8800-2024-3928","url":null,"abstract":"According to the recent World Health Organization statistics, cardiovascular disease (CVD) is one of the leading causes of high mortality worldwide. While obesity is a major and persistent risk factor for CVD, the cause of this condition, the pathological molecular connection between peripheral fat depots and the heart, remains poorly understood. The aim of this review is to introduce the reader to the metabolic activity of epicardial adipose tissue (EAT), the consequences of excessive epicardial fat accumulation and the development of heart failure (HF).EAT is visceral adipose tissue that is in direct contact with the myocardium and coronary vessels and can influence cardiac function through both mechanical effects and more subtle paracrine molecular mechanisms. HF with preserved ejection fraction (HFpEF) is closely associated with obesity and patterns in fat distribution. Excessive amounts of EAT are associated with abnormal hemodynamics in HFpEF, with the potential for direct mechanical effects on the heart causing a constriction-like effect and local myocardial remodeling effects resulting from the secretion of inflammatory mediators. However, patients with excess EAT tend to have more subcutaneous adipose tissue, making it difficult to determine a cause-and-effect relationship between epicardial fat and HFpEF. This review provides evidence that excess EAT is an important part of HFpEF pathogenesis.","PeriodicalId":504164,"journal":{"name":"Cardiovascular Therapy and Prevention","volume":"36 142","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140708156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Mershina, D. Filatova, R. Myasnikov, O. Kulikova, A. N. Meshkov, A. Kiseleva, V. Sinitsyn, M. Kharlap
{"title":"Role of cardiac magnetic resonance imaging in assessing the risk of various myocardial remodeling types in left ventricular noncompaction: genetic analysis data","authors":"E. Mershina, D. Filatova, R. Myasnikov, O. Kulikova, A. N. Meshkov, A. Kiseleva, V. Sinitsyn, M. Kharlap","doi":"10.15829/1728-8800-2024-3899","DOIUrl":"https://doi.org/10.15829/1728-8800-2024-3899","url":null,"abstract":"Aim. To analyze contrast-enhanced cardiac magnetic resonance imaging (MRI) in patients with phenotypic manifestations of left ventricular non-compaction (LVNC) and related genetic mutations, as well as to determine the relationship between mutations and types of left ventricular (LV) remodeling and with a number of other morphological and functional cardiac parameters.Material and methods. From the registry of patients with LVNC and their relatives, patients with morphological signs of LVNC and 4 related mutations (MYH7, MYBPC3, TTN, and desmin genes (DES, DSG2, DSP and DSC2)). All patients underwent contrast-enhanced cardiac MRI, based on which the type of LV remodeling was determined.Results. The study included 44 patients who, according to genetic analysis, had mutations in sarcomeric genes responsible for LVNC development. In each patient, the type of LV remodeling was determined based on cardiac MRI results. We found that if patients with LVNC have mutations in the MYBPC3 and TTN genes, the chance of LV dilatation remodeling is significantly higher. On the contrary, in the presence of a DES gene mutation, the probability of this LV remodeling is lower, and milder morphological manifestations of LVNC are noted.Conclusion. The combination of cardiac MRI data and genetic analysis improves the morphological and functional stratification of patients with LVNC.","PeriodicalId":504164,"journal":{"name":"Cardiovascular Therapy and Prevention","volume":"103 S1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140707400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Differing treatment pathways for the management of hypertension: long-term clinical projections in Russia","authors":"A. V. Rodionov, D. Granados, A. Kontsevaya","doi":"10.15829/1728-8800-2024-3328","DOIUrl":"https://doi.org/10.15829/1728-8800-2024-3328","url":null,"abstract":"Aim. Management of hypertension, a major cause of mortality worldwide, is difficult, with adherence a common problem. The present study aimed to estimate the long-term clinical outcomes associated with different treatment pathways in people with hypertension in Russia.Material and methods. Outcomes were projected over 10 years using a microsimulation model. Four treatment pathways (current treatment practices (CTP), single drug with dosage titration then sequential addition of other agents [start low and go slow, SLGS], free choice combination with multiple pills (FCC) and combination therapy in a single pill (SPC)) were evaluated based on the Global Burden of Disease 2017 dataset. Clinical outcomes were simulated for 1,000,000 individuals for each pathway.Results. Long-term projections associated SPC therapy with reductions in mortality (4.9%), disability-adjusted life years (DALYs, 5.2%), and incidence of complications (including chronic kidney disease, stroke and ischemic heart disease, 9.2%) versus CTP, with greater reductions in all outcomes versus SLGS and FCC. SPC was projected to save 1,193 DALYs compared with CTP over 10 years. Adherence was identified as a key driver in the analysis.Conclusion. Based on 10-year projections, combination therapies (including SPC and FCC) appear likely to reduce the burden of hypertension compared with conventional treatment options in Russia.","PeriodicalId":504164,"journal":{"name":"Cardiovascular Therapy and Prevention","volume":"59 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140707985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Podzolkov, A. Tarzimanova, L. Ponomareva, A. A. Ivannikov, A. A. Chinova, E. N. Popova, A. B. Ponomarev, O. A. Morozova, L. G. Gladun, A. Y. Isaeva
{"title":"The role of Pseudomonas aeruginosa pneumonia in the development of cardiovascular events in patients with heart failure","authors":"V. Podzolkov, A. Tarzimanova, L. Ponomareva, A. A. Ivannikov, A. A. Chinova, E. N. Popova, A. B. Ponomarev, O. A. Morozova, L. G. Gladun, A. Y. Isaeva","doi":"10.15829/1728-8800-2024-3853","DOIUrl":"https://doi.org/10.15829/1728-8800-2024-3853","url":null,"abstract":"Aim. To assess the contribution of Pseudomonas aeruginosa pneumonia to the development of cardiovascular events in patients with heart failure (HF).Material and methods. The study included 219 patients who were divided into a group of patients with pneumonia caused by P. aeruginosa (Group I) and a group of patients with pneumonia caused by S. aureus, S. pneumoniae (Group II). All patients underwent chest computed tomography (CT), blood tests, echocardiography, electrocardiography (ECG), 24-hour Holter ECG monitoring, pulse oximetry (SpO2), and Doppler ultrasound of the lower limb veins.Results. According to the study, cardiovascular events were more often observed in the group of patients with P. aeruginosa pneumonia as follows: death from cardiovascular events was registered in 11,4% of patients in group I and 0% of patients in group II (p=0,001); acute coronary syndrome — in 8,7 vs 0% (p=0,002), lower limb thrombosis — in 14 vs 1,9% (p=0,001). The occurrence of P. aeruginosa pneumonia in patients with HF increased the cardiovascular death risk by 8,8 times (95% confidence interval (CI): 1,2-65,7; p=0,005), acute coronary syndrome — in 8,0 times (95% CI: 1,1-60,2; p=0,014), lower limb thrombosis — in 9,6 times (95% CI: 1,3-71,2; p=0,004).Conclusion. Patients with HF and P. aeruginosa pneumonia are at greater risk of cardiovascular events than patients with pneumonia caused by S. pneumonia and S. aureus.","PeriodicalId":504164,"journal":{"name":"Cardiovascular Therapy and Prevention","volume":"37 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140708613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Zelenina, S. Shalnova, G. Muromtseva, A. Kapustina, Y. Balanova, S. T. Evstifeeva, A. Imaeva, N. S. Karamnova, O. B. Shvabskaya, S. A. Maksimov
{"title":"Association between cardiovascular mortality and deprivation in the adult population of Russia","authors":"A. Zelenina, S. Shalnova, G. Muromtseva, A. Kapustina, Y. Balanova, S. T. Evstifeeva, A. Imaeva, N. S. Karamnova, O. B. Shvabskaya, S. A. Maksimov","doi":"10.15829/1728-8800-2024-3903","DOIUrl":"https://doi.org/10.15829/1728-8800-2024-3903","url":null,"abstract":"According to the Federal State Statistics Service of Russia, from 1970 to 2019, cardiovascular diseases remain one of the main causes of death in Russia. To date, the relationship between cardiovascular mortality and deprivation in Russia remains insufficiently studied.Aim. To identify the relationship between regional deprivation and cardiovascular mortality among the adult population of Russia.Material and methods. The Russian deprivation index was used to measure the deprivation level. The index indicators were obtained from official Rosstat statistics and the All-Russian Population Census for 2010. Cardiovascular mortality by age (five-year groups) and sex in the constituent entities of Russia from 2006 to 2012 was obtained from the Russian database on fertility and mortality of the Center for Demographic Research of the Russian Economic School.Results. The fully adjusted model showed a reduction in mortality (Mortality Rate Ratio (MRR), 0,93; 95% confidence interval: 0,91-0,94) in regions with the greatest overall deprivation compared to the least deprived regions. There is a decrease in mortality in the most socially deprived regions compared to the least deprived ones. The fully adjusted model showed a trend toward increased mortality across levels of economic deprivation (from less deprived (Q2) to more deprived (Q3 and Q4) compared to least deprived regions (Q1)). Our study showed an increase in mortality in the most environmentally deprived regions — MRR, 1,02; 95% confidence interval: 1,00-1,04.Conclusion. The study established a link between general, social, economic and environmental deprivation and cardiovascular mortality.","PeriodicalId":504164,"journal":{"name":"Cardiovascular Therapy and Prevention","volume":"66 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140708456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Drapkina, A. Kontsevaya, A. M. Kalinina, S. N. Avdeev, M. Agaltsov, L. I. Alekseeva, I. I. Almazova, E. Andreenko, D. N. Antipushina, Y. Balanova, S. Berns, A. Budnevsky, V. V. Gainitdinova, A. Garanin, V. M. Gorbunov, A. Y. Gorshkov, E. A. Grigorenko, B. Y. Jonova, L. Drozdova, I. V. Druk, S. Eliashevich, M. S. Eliseev, G. Zharylkasynova, S. A. Zabrovskaya, A. Imaeva, U. Kamilova, A. Kaprin, Z. Kobalava, D. V. Korsunsky, O. Kulikova, A. Kurekhyan, N. Kutishenko, E. Lavrenova, M. Lopatina, Yy. V. Lukina, M. M. Lukyanov, E. O. Lyusina, M. N. Mamedov, B. Mardanov, Y. Mareev, S. Martsevich, N. Mitkovskaya, R. Myasnikov, D. V. Nebieridze, S. Orlov, K. Pereverzeva, O. E. Popovkina, V. I. Potievskaya, I. Skripnikova, M. I. Smirnova, T. M. Sooronbaev, N. Toroptsova, Zh. V. Khailova, V. E. Khoronenko, M. G. Chashchin, T. Chernik, S. Shalnova, M. Shapovalova, R. Shepel, A. Sheptulina, V. N. Shishkova, R. U. Yuldashova, I. Yavelov, S. Yakushin
{"title":"Comorbidity of patients with noncommunicable diseases in general practice. Eurasian guidelines","authors":"O. Drapkina, A. Kontsevaya, A. M. Kalinina, S. N. Avdeev, M. Agaltsov, L. I. Alekseeva, I. I. Almazova, E. Andreenko, D. N. Antipushina, Y. Balanova, S. Berns, A. Budnevsky, V. V. Gainitdinova, A. Garanin, V. M. Gorbunov, A. Y. Gorshkov, E. A. Grigorenko, B. Y. Jonova, L. Drozdova, I. V. Druk, S. Eliashevich, M. S. Eliseev, G. Zharylkasynova, S. A. Zabrovskaya, A. Imaeva, U. Kamilova, A. Kaprin, Z. Kobalava, D. V. Korsunsky, O. Kulikova, A. Kurekhyan, N. Kutishenko, E. Lavrenova, M. Lopatina, Yy. V. Lukina, M. M. Lukyanov, E. O. Lyusina, M. N. Mamedov, B. Mardanov, Y. Mareev, S. Martsevich, N. Mitkovskaya, R. Myasnikov, D. V. Nebieridze, S. Orlov, K. Pereverzeva, O. E. Popovkina, V. I. Potievskaya, I. Skripnikova, M. I. Smirnova, T. M. Sooronbaev, N. Toroptsova, Zh. V. Khailova, V. E. Khoronenko, M. G. Chashchin, T. Chernik, S. Shalnova, M. Shapovalova, R. Shepel, A. Sheptulina, V. N. Shishkova, R. U. Yuldashova, I. Yavelov, S. Yakushin","doi":"10.15829/1728-8800-2024-3996","DOIUrl":"https://doi.org/10.15829/1728-8800-2024-3996","url":null,"abstract":"Создание руководства поддержано Советом по терапевтическим наукам отделения клинической медицины Российской академии наук.","PeriodicalId":504164,"journal":{"name":"Cardiovascular Therapy and Prevention","volume":"31 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140789814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
