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Universal solvent-adaptive fluorescent AZ NPs-ACh sensor for reliable visual detection of organophosphorus pesticides via AChE-H2O2 signaling 通用溶剂自适应荧光AZ NPs-ACh传感器，通过AChE-H2O2信号可靠的视觉检测有机磷农药

Frontiers in Sensors Pub Date : 2026-04-17 DOI: 10.3389/fsens.2026.1756022

Huilan Hu, Yunshu Zhang, Linlin Wang, Yun Wu, 盛开泉, Zhijian Zeng, Shuying Yuan, Yibao Jin, Lan Ma, Jiangwei Tian, Bing Wang

{"title":"Universal solvent-adaptive fluorescent AZ NPs-ACh sensor for reliable visual detection of organophosphorus pesticides via AChE-H2O2 signaling","authors":"Huilan Hu, Yunshu Zhang, Linlin Wang, Yun Wu, 盛开泉, Zhijian Zeng, Shuying Yuan, Yibao Jin, Lan Ma, Jiangwei Tian, Bing Wang","doi":"10.3389/fsens.2026.1756022","DOIUrl":"https://doi.org/10.3389/fsens.2026.1756022","url":null,"abstract":"Organophosphorus pesticides (OPs) pose a serious threat to public health and food safety through irreversible inhibition of acetylcholinesterase (AChE) activity, so the development of a visual detection method suitable for complex matrices is urgent. In this work, a novel fluorescence sensor was constructed based on the coordination assembly of gold-silver nanoclusters (AuAg NCs) with zinc ions (Zn 2+ ), which exhibits a characteristic fluorescence peak at an excitation wavelength of 310 nm and an emission wavelength of 690 nm, and enables specific recognition and detection of hydrogen peroxide (H 2 O 2 ). The detection system utilizes OPs as inhibitors of AChE, enabling quantitative monitoring of OPs by detecting the concentration of H 2 O 2 generated through the synergistic catalysis of AChE and its cascade enzyme choline oxidase (ChOx). Notably, in practical analyses, the sensor demonstrates excellent fluorescence response characteristics across various solvents. Particularly in the complex matrix of traditional Chinese medicine (TCM) such as: Chenpi samples, the sensor achieves accurate quantitative analysis of OPs, exhibiting a linear relationship within the range of 1–200 ng/mL. Furthermore, the sensor can be integrated onto a paper-based carrier, enabling semi-quantitative analysis of pesticide residues at the field site using a portable UV lamp, demonstrating significant practical application potential.","PeriodicalId":503841,"journal":{"name":"Frontiers in Sensors","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://public-pages-files-2025.frontiersin.org/journals/sensors/articles/10.3389/fsens.2026.1756022/pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148305722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A method for evaluating the risks of glucose dysregulation in daily life by continuous measurement of glucose excursions under reduced glycemic load: a pilot study 在降低血糖负荷的情况下，通过连续测量血糖偏移量来评估日常生活中血糖失调风险的方法：一项试点研究

Frontiers in Sensors Pub Date : 2024-05-07 DOI: 10.3389/fsens.2024.1382152

Yoshitada Katagiri, Hiromi Ozaku, Katsuhiko Kondo

{"title":"A method for evaluating the risks of glucose dysregulation in daily life by continuous measurement of glucose excursions under reduced glycemic load: a pilot study","authors":"Yoshitada Katagiri, Hiromi Ozaku, Katsuhiko Kondo","doi":"10.3389/fsens.2024.1382152","DOIUrl":"https://doi.org/10.3389/fsens.2024.1382152","url":null,"abstract":"Introduction: Continuous glucose monitoring is essential for the management of patients with metabolic syndromes in their daily lives. However, how metabolic risks are accessed using time-series glucose excursion data for healthy individuals remains unclear.Methods: Thus, this study aimed to present a method for evaluating the risks of glucose dysregulation by analyzing glucose responses under reduced glycemic load using a phytochemical alpha-glucosidase inhibitor. A 14-day pilot trial with healthy adult participants was conducted to demonstrate the validity of the method.Results and Discussion: The results showed that ultradian glucose spike packets with lower heights dominantly appeared under reduced glycemic load, replacing postprandial single-lobe glucose spikes with higher heights. Furthermore, the frequency dominance of ultradian spike packets contributed to the reduction of overall mean glucose excursions during the test period under reduced glycemic load. Based on the time-delay model, it was indicated that glycemic load reduction recovers regular glucose–insulin coupling accompanying ultradian oscillations, thereby contributing to the maintenance of glucose homeostasis. The findings of this study indicate that the frequency ratio between pulsatile spike packets and single-lobe spikes could be a marker for evaluating glucose regulation/dysregulation in healthy adults.","PeriodicalId":503841,"journal":{"name":"Frontiers in Sensors","volume":"61 3‐4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141004131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diffusiophoresis: a novel transport mechanism - fundamentals, applications, and future opportunities 扩散电泳：一种新型传输机制--基础、应用和未来机遇

Frontiers in Sensors Pub Date : 2023-11-30 DOI: 10.3389/fsens.2023.1322906

Arkava Ganguly, Benjamin M. Alessio, Ankur Gupta

{"title":"Diffusiophoresis: a novel transport mechanism - fundamentals, applications, and future opportunities","authors":"Arkava Ganguly, Benjamin M. Alessio, Ankur Gupta","doi":"10.3389/fsens.2023.1322906","DOIUrl":"https://doi.org/10.3389/fsens.2023.1322906","url":null,"abstract":"Diffusiophoresis involves the movement of colloidal-scale entities in response to concentration gradients of a solute. It is broadly categorized into two types: passive and active diffusiophoresis. In passive diffusiophoresis, external concentration gradients drive the motion, while in active diffusiophoresis, the colloidal entity itself assists in generating the gradients. In this perspective, we delve into the fundamental processes underlying passive and active diffusiophoresis and emphasize how prevalent both kinds of diffusiophoresis are in colloidal and natural systems. In particular, we highlight the colloidal focusing feature in passive diffusiophoresis and discuss how it underpins the variety of experimental observations and applications such as low-cost zetasizers, water filtration, and biological pattern formation. For active diffusiophoresis, we emphasize the dependence of particle trajectory on its shape and surface heterogeneity, and discuss how this dictates the applications such as drug delivery, removal of microplastics, and self-repairing materials. Finally, we offer insights and ideas regarding future opportunities in diffusiophoresis.","PeriodicalId":503841,"journal":{"name":"Frontiers in Sensors","volume":"19 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139196965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0