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Clinical Efficacy of Autologous Simple Limbal Epithelial Transplantation for Stem Cell Deficiency in Ocular Surface Burn 自体单纯睑缘上皮移植治疗眼表烧伤干细胞缺乏症的临床疗效
Cornea Open Pub Date : 2024-03-01 DOI: 10.1097/coa.0000000000000030
Zaman Shah, Ibrar Hussain, Khalid Mehmood, Inayatullah Khan, Pir Salim Mahar, N. Butt
{"title":"Clinical Efficacy of Autologous Simple Limbal Epithelial Transplantation for Stem Cell Deficiency in Ocular Surface Burn","authors":"Zaman Shah, Ibrar Hussain, Khalid Mehmood, Inayatullah Khan, Pir Salim Mahar, N. Butt","doi":"10.1097/coa.0000000000000030","DOIUrl":"https://doi.org/10.1097/coa.0000000000000030","url":null,"abstract":"","PeriodicalId":503185,"journal":{"name":"Cornea Open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140086346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Native Australian Bronze Orange Stink Bug (Musgraveia sulciventris)–Related Corneal Injury 与澳大利亚本地青铜橙色臭虫(Musgraveia sulciventris)有关的角膜损伤
Cornea Open Pub Date : 2024-03-01 DOI: 10.1097/coa.0000000000000031
Aishwariya Seshakumaran
{"title":"Native Australian Bronze Orange Stink Bug (Musgraveia sulciventris)–Related Corneal Injury","authors":"Aishwariya Seshakumaran","doi":"10.1097/coa.0000000000000031","DOIUrl":"https://doi.org/10.1097/coa.0000000000000031","url":null,"abstract":"\u0000 The bronze orange stink bug (Musgraveia sulciventris) is an insect native to Australia that is found in citrus trees and gardens in coastal Queensland and New South Wales. The common name “stink bug” is attributed to the foul spray emitted from these insects when they are threatened. This spray can result in corneal injuries; however, human case reports of stink bug bodily fluid exposure to the eye are rare and have not been previously reported for this species. This report describes a case of the native Australian insect bronze orange stink bug causing irritant contact keratitis in the eye, which is the only reported case in the literature. Patients who garden in Queensland and New South Wales should be advised to handle these insects with care, by wearing protective eyewear and gloves when handling citrus trees or when removing them from their gardens, to minimize their risk of corneal damage if sprayed.","PeriodicalId":503185,"journal":{"name":"Cornea Open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140273280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ocular Surface Analysis of Dry Eye Disease After Cataract Surgery 白内障手术后干眼症的眼表分析
Cornea Open Pub Date : 2024-02-02 DOI: 10.1097/coa.0000000000000027
W. Tangpagasit, Onnicha Srivanich
{"title":"Ocular Surface Analysis of Dry Eye Disease After Cataract Surgery","authors":"W. Tangpagasit, Onnicha Srivanich","doi":"10.1097/coa.0000000000000027","DOIUrl":"https://doi.org/10.1097/coa.0000000000000027","url":null,"abstract":"\u0000 \u0000 We aimed to compare the efficacy and safety of 0.3% hydroxypropyl methylcellulose/dextran (HPMC/Dextran) and 0.3% sodium hyaluronate (SH) in the treatment of dry eye disease (DED) in postcataract surgery patients by analyzing the presurgery and postsurgery ocular surface.\u0000 \u0000 \u0000 \u0000 This double-blinded, randomized, parallel-group study enrolled 96 patients with ocular surface dysfunction, specifically DED, after phacoemulsification. Patients were randomized to receive either HPMC/Dextran (n = 56) or 0.3% SH (n = 40). All patients received 1 drop per eye, 4 times per day. Data from OCULUS Keratograph 5M and Schirmer I tests without anesthesia were collected at baseline and 1 week, 1 month, and 3 months postoperatively.\u0000 \u0000 \u0000 \u0000 Three months postsurgery, the ocular surface, Schirmer I test, tear meniscus height (TMH), noninvasive tear film break-up time (NITBUT), meibography, redness, and Ocular Surface Disease Index were significantly improved. The Schirmer I test, TMH, and NITBUT improved significantly (P = 0.07, 0.17, and 0.43, respectively; analysis of variance, P < 0.05) in the SH group compared with the HPMC/Dextran group. In a subgroup analysis of patients with severe dry eye, Schirmer I test ≤ 5 mm/5 minutes and NITBUT < 5 significantly improved (P = 0.00 and 0.001, respectively) at 3 months in the SH group compared with the HPMC/Dextran group. Thus, 0.3% SH gave significantly superior tear secretion and tear film instability outcomes.\u0000 \u0000 \u0000 \u0000 Both types of preservative-free artificial tears are effective in treating postsurgery DED. Compared with HPMC/Dextran, 0.3% SH artificial tears showed more improvements in Schirmer I test and NITBUT postsurgery.\u0000","PeriodicalId":503185,"journal":{"name":"Cornea Open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139810570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ocular Surface Analysis of Dry Eye Disease After Cataract Surgery 白内障手术后干眼症的眼表分析
Cornea Open Pub Date : 2024-02-02 DOI: 10.1097/coa.0000000000000027
W. Tangpagasit, Onnicha Srivanich
{"title":"Ocular Surface Analysis of Dry Eye Disease After Cataract Surgery","authors":"W. Tangpagasit, Onnicha Srivanich","doi":"10.1097/coa.0000000000000027","DOIUrl":"https://doi.org/10.1097/coa.0000000000000027","url":null,"abstract":"\u0000 \u0000 We aimed to compare the efficacy and safety of 0.3% hydroxypropyl methylcellulose/dextran (HPMC/Dextran) and 0.3% sodium hyaluronate (SH) in the treatment of dry eye disease (DED) in postcataract surgery patients by analyzing the presurgery and postsurgery ocular surface.\u0000 \u0000 \u0000 \u0000 This double-blinded, randomized, parallel-group study enrolled 96 patients with ocular surface dysfunction, specifically DED, after phacoemulsification. Patients were randomized to receive either HPMC/Dextran (n = 56) or 0.3% SH (n = 40). All patients received 1 drop per eye, 4 times per day. Data from OCULUS Keratograph 5M and Schirmer I tests without anesthesia were collected at baseline and 1 week, 1 month, and 3 months postoperatively.\u0000 \u0000 \u0000 \u0000 Three months postsurgery, the ocular surface, Schirmer I test, tear meniscus height (TMH), noninvasive tear film break-up time (NITBUT), meibography, redness, and Ocular Surface Disease Index were significantly improved. The Schirmer I test, TMH, and NITBUT improved significantly (P = 0.07, 0.17, and 0.43, respectively; analysis of variance, P < 0.05) in the SH group compared with the HPMC/Dextran group. In a subgroup analysis of patients with severe dry eye, Schirmer I test ≤ 5 mm/5 minutes and NITBUT < 5 significantly improved (P = 0.00 and 0.001, respectively) at 3 months in the SH group compared with the HPMC/Dextran group. Thus, 0.3% SH gave significantly superior tear secretion and tear film instability outcomes.\u0000 \u0000 \u0000 \u0000 Both types of preservative-free artificial tears are effective in treating postsurgery DED. Compared with HPMC/Dextran, 0.3% SH artificial tears showed more improvements in Schirmer I test and NITBUT postsurgery.\u0000","PeriodicalId":503185,"journal":{"name":"Cornea Open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139870197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Allogenic Simple Limbal Epithelial Transplantation: An Approach to Bilateral Recurrent Pterygia and Limbal Stem Cell Deficiency 异基因单纯睑缘上皮移植:治疗双侧复发性翼状胬肉和角膜干细胞缺乏症的方法
Cornea Open Pub Date : 2024-01-24 DOI: 10.1097/coa.0000000000000028
Shefali Mazumdar, Samya Singh, Nandini Asija, Lavi Madhur
{"title":"Allogenic Simple Limbal Epithelial Transplantation: An Approach to Bilateral Recurrent Pterygia and Limbal Stem Cell Deficiency","authors":"Shefali Mazumdar, Samya Singh, Nandini Asija, Lavi Madhur","doi":"10.1097/coa.0000000000000028","DOIUrl":"https://doi.org/10.1097/coa.0000000000000028","url":null,"abstract":"\u0000 A 44-year-old man presented with bilateral total limbal stem cell deficiency after multiple failed surgeries for recurrent pterygia in both eyes over the last 11 years. His best corrected visual acuity (BCVA) in both eyes at the time of presentation was hand movement, projection of rays accurate. Owing to bilateral involvement, allogenic simple limbal epithelial transplantation (Allo SLET) was performed in the right eye. The limbal biopsy was taken from the wife of the patient. Complete ocular surface epithelialization was achieved in 26 days. The patient has completed 15 months of postoperative follow-up with stable ocular surface and BCVA 6/12 in the RE. He is on systemic and topical immunosuppressants with no side effects to date.","PeriodicalId":503185,"journal":{"name":"Cornea Open","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139601308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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