Journal of Systematics and Evolution最新文献

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Convergent evolution of glutathione metabolism pathway genes in marine mammals 海洋哺乳动物谷胱甘肽代谢途径基因的趋同进化

Journal of Systematics and Evolution Pub Date : 2025-11-25 DOI: 10.1111/jse.70031

Zhihong Jin, Jie Jiang, Tinghui Li, Simin Chai, Ran Tian

{"title":"Convergent evolution of glutathione metabolism pathway genes in marine mammals","authors":"Zhihong Jin, Jie Jiang, Tinghui Li, Simin Chai, Ran Tian","doi":"10.1111/jse.70031","DOIUrl":"https://doi.org/10.1111/jse.70031","url":null,"abstract":"Abstract Oxidative stress, triggered by hypoxia during repetitive diving, represents a notable environmental adaptation of marine mammals. Glutathione (GSH) is a widely acknowledged antioxidant that protects crucial cellular elements from damage by reactive oxygen species (ROS). Nevertheless, the role of the glutathione metabolism pathway in shaping the adaptation to oxidative stress in marine mammals is not fully elucidated. In this study, we conducted evolutionary analyses on 37 genes related to the GSH metabolism pathway in marine and terrestrial mammals. We found that in comparison with their terrestrial relatives, marine mammals showed convergently accelerated evolution on the core modules of GSH metabolism. Specifically, we identified a total of 16 genes with significant evolution signals unique to marine mammals, and several genes (e.g., accelerated evolution genes: RRM1 and SMS , positively selected genes: ANPEP and GCLC ) were shared in marine mammal lineages. Eight genes were discovered to possess specific amino acid modifications that are common among all marine mammals. Functional assays of marine mammal GCLC showed a downregulation of HIF‐1α and enhanced GSH levels under hypoxic conditions, suggesting heightened protection of marine mammals against oxidative stress induced by hypoxia. Our study identified key genes with significant evolutionary signals in marine mammals, providing genomic and functional support for convergent hypoxia adaptation mechanisms within this taxon.","PeriodicalId":502547,"journal":{"name":"Journal of Systematics and Evolution","volume":"64 2","pages":"283-294"},"PeriodicalIF":0.0,"publicationDate":"2025-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jse.70031","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147900131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Alpine refugial isolation drove divergence of the cold‐adapted montane scorpionfly Cerapanorpa obtusa (Mecoptera: Panorpidae) 高山避难隔离对高山寒适应蝎的分化驱动（鞘翅目：全景科）

Journal of Systematics and Evolution Pub Date : 2024-12-18 DOI: 10.1111/jse.13150

Kai Gao, Yuan Hua, Le‐Le He, Bao‐Zhen Hua

{"title":"Alpine refugial isolation drove divergence of the cold‐adapted montane scorpionfly <i>Cerapanorpa obtusa</i> (Mecoptera: Panorpidae)","authors":"Kai Gao, Yuan Hua, Le‐Le He, Bao‐Zhen Hua","doi":"10.1111/jse.13150","DOIUrl":"https://doi.org/10.1111/jse.13150","url":null,"abstract":"Abstract Quaternary climate fluctuations and complex mountain systems had a prominent impact on the genetic diversification and speciation of montane organisms. However, the genetic imprints of the interplay between past climate events and rugged relief on montane species remain largely unresolved. Here, we analyzed the phylogeny, population structure, divergence time, demographic simulations, and ecological niche modeling of the montane scorpionfly Cerapanorpa obtusa (Cheng) from 36 populations in the mountains of central China (MCC) using three mitochondrial and two nuclear genes to explore its evolutionary history. The results show that C. obtusa originated from the Minshan Mountains, and currently consists of six genetically fragmented lineages that diverged 1.25–0.52 Ma. Four minor lineages (S1−S4) are confined to the topographically rugged Minshan Mountains, and two major lineages (NW and NE) are widely distributed in the northern MCC with relatively homogeneous landscapes. The Minshan Mountains are likely interglacial microrefugia for C. obtusa , and as spatial buffers in response to past climate changes. These findings provide some evidence that the interplay between climate changes and rugged relief may play a significant role in shaping the distinct phylogeographical pattern of cold‐adapted montane insects. These results would also seem to suggest the importance of topographically rugged mountain systems in the conservation of evolutionary diversity and endemic species.","PeriodicalId":502547,"journal":{"name":"Journal of Systematics and Evolution","volume":"63 3","pages":"753-766"},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147919190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0