FEMS Microbes最新文献

Gut microbiome in two high-altitude bird populations showed heterogeneity in sex and life stage 两个高海拔鸟类种群的肠道微生物组显示出性别和生命阶段的异质性

FEMS Microbes Pub Date : 2024-07-04 DOI: 10.1093/femsmc/xtae020

Mingwan Sun, Naerhulan Halimubieke, Baozhu Fang, J. Valdebenito, Xieyang Xu, Samuel K Sheppard, Tamás Székely, Tongzuo Zhang, Shunfu He, Rong Lu, Stephen Ward, Araxi O. Urrutia, Yang Liu

{"title":"Gut microbiome in two high-altitude bird populations showed heterogeneity in sex and life stage","authors":"Mingwan Sun, Naerhulan Halimubieke, Baozhu Fang, J. Valdebenito, Xieyang Xu, Samuel K Sheppard, Tamás Székely, Tongzuo Zhang, Shunfu He, Rong Lu, Stephen Ward, Araxi O. Urrutia, Yang Liu","doi":"10.1093/femsmc/xtae020","DOIUrl":"https://doi.org/10.1093/femsmc/xtae020","url":null,"abstract":"\u0000 Gut microbiotas have important impacts on host health, reproductive success, and survival. While extensive research in mammals has identified the exogenous (e.g. environment) and endogenous (e.g. phylogeny, sex and age) factors that shape the gut microbiota composition and functionality, yet avian systems remain comparatively less understood. Shorebirds, characterised by a well-resolved phylogeny and diverse life-history traits, present an ideal model for dissecting the factors modulating gut microbiota dynamics. Here, we provide an insight into the composition of gut microbiota in two high-altitude (ca. 3200m a.s.l.) breeding populations of Kentish plover (Charadrius alexandrinus) and Tibetan sand plover (Charadrius altrifrons) in Qinghai-Tibetan Plateau, China. By analysing faecal bacterial communities using 16S rRNA sequencing technology, we find a convergence in gut microbial communities between the two species, dominated by Firmicutes, Proteobacteria and Bacteroidetes. This suggests that the shared breeding environment potentially acts as a significant determinant shaping their gut microbiota. We also show sex- and age-specific patterns of gut microbiota: female adults maintain a higher diversity than males, and juveniles are enriched in Rhizobiaceae and Exiguobacterium due to their vegetative food resource. Our study not only provides a comprehensive descriptive information for future investigations on the diversity, functionality and determinants of avian microbiomes, but also underscores the importance of microbial communities in broader ecological contexts.","PeriodicalId":502482,"journal":{"name":"FEMS Microbes","volume":" 27","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141680255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Heme utilization by the enterococci 肠球菌对血红素的利用

FEMS Microbes Pub Date : 2024-07-02 DOI: 10.1093/femsmc/xtae019

Debra N. Brunson, José A Lemos

{"title":"Heme utilization by the enterococci","authors":"Debra N. Brunson, José A Lemos","doi":"10.1093/femsmc/xtae019","DOIUrl":"https://doi.org/10.1093/femsmc/xtae019","url":null,"abstract":"\u0000 Heme consists of a tetrapyrrole ring ligating an iron ion and has important roles in biological systems. While well known as the oxygen binding molecule within hemoglobin of mammals, heme is also cofactor for several enzymes and a major iron source for bacteria within the host. The enterococci are a diverse group of Gram-positive bacteria that exist primarily within the gastrointestinal tract of animals. However, some species within this genus can transform into formidable opportunistic pathogens, largely owing to their extraordinary adaptability to hostile environments. Although enterococci cannot synthesize heme nor depend on heme to grow, several species within the genus encode proteins that utilize heme as a cofactor, which appears to increase their fitness and ability to thrive in challenging environments. This includes more efficient energy generation via aerobic respiration and protection from reactive oxygen species. Here, we review the significance of heme to enterococci, primarily the major human pathogen Enterococcus faecalis, use bioinformatics to assess the prevalence of hemoproteins throughout the genus, and highlight recent studies that underscore the central role of the heme-E. faecalis relationship in host-pathogen dynamics and interspecies bacterial interactions.","PeriodicalId":502482,"journal":{"name":"FEMS Microbes","volume":"29 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141685238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atmospheric dispersal shapes rapid bacterial colonization of Icelandic Lava Rocks 大气散布形成冰岛熔岩中细菌的快速定殖

FEMS Microbes Pub Date : 2024-05-24 DOI: 10.1093/femsmc/xtae016

Aurélien Daussin, Pauline Vannier, Lola Daboussy, Tina Šantl-Temkiv, Charles Cockell, Viggó Þór Marteinsson

{"title":"Atmospheric dispersal shapes rapid bacterial colonization of Icelandic Lava Rocks","authors":"Aurélien Daussin, Pauline Vannier, Lola Daboussy, Tina Šantl-Temkiv, Charles Cockell, Viggó Þór Marteinsson","doi":"10.1093/femsmc/xtae016","DOIUrl":"https://doi.org/10.1093/femsmc/xtae016","url":null,"abstract":"\u0000 Microorganisms released into the atmosphere by various disturbances can travel significant distances before depositing, yet their impact on community assembly remains unclear. To address this, we examined atmospheric and lithospheric bacterial communities in 179 samples collected at two distinct Icelandic volcanic sites: a small volcanic island Surtsey, and a volcanic highland Fimmvörðuháls using 16S rRNA amplicon sequencing.\u0000 Airborne microbial communities were similar between sites while significant differences emerged in the communities on lava rocks after 1-year exposure. SourceTracker analysis revealed distinct bacterial populations in the atmosphere and the lava rocks with surrounding soil contributed more significantly to lava rock microbial composition. Nevertheless, shared genera among air, rocks, and local sources, suggested potential exchange between these environments. The prevalent genera shared between rocks and potential sources exhibited stress-resistant properties, likely helping their survival during air transportation and facilitating their colonization of the rocks. We hypothesize that the atmosphere serves as a conduit for locally sourced microbes and stress-resistant distant-sourced microbes. Additionally, bacterial communities on the lava rocks of Fimmvörðuháls showed remarkable similarity after 1 and 9 years of exposure, suggesting rapid establishment. Our study reveals that atmospheric deposition significantly influences bacterial community formation, potentially influencing ecosystem dynamics and microbial communities’ resilience.","PeriodicalId":502482,"journal":{"name":"FEMS Microbes","volume":"12 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141099772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

YajC, a predicted membrane protein, promotes Enterococcus faecium biofilm Formation in vitro and in a rat endocarditis model YajC 是一种预测的膜蛋白，可促进粪肠球菌生物膜在体外和大鼠心内膜炎模型中的形成

FEMS Microbes Pub Date : 2024-05-20 DOI: 10.1093/femsmc/xtae017

Janetta Top, Xinglin Zhang, Antoni P. A. Hendrickx, S. Boeren, Willem van Schaik, Johannes Huebner, Rob J. L. Willems, H. Leavis, F. Paganelli

{"title":"YajC, a predicted membrane protein, promotes Enterococcus faecium biofilm Formation in vitro and in a rat endocarditis model","authors":"Janetta Top, Xinglin Zhang, Antoni P. A. Hendrickx, S. Boeren, Willem van Schaik, Johannes Huebner, Rob J. L. Willems, H. Leavis, F. Paganelli","doi":"10.1093/femsmc/xtae017","DOIUrl":"https://doi.org/10.1093/femsmc/xtae017","url":null,"abstract":"\u0000 Biofilm formation is a critical step in the pathogenesis of difficult-to-treat Gram-positive bacterial infections. We identified that YajC, a conserved membrane protein in bacteria, plays a role in biofilm formation of the clinically relevant Enterococcus faecium strain E1162. Deletion of yajC conferred significantly impaired biofilm formation in vitro and was attenuated in a rat endocarditis model. Mass-spectrometry analysis of supernatants of washed ΔyajC cells revealed increased amounts in cytoplasmic and cell-surface located proteins, including biofilm-associated proteins, suggesting that proteins on the surface of the yajC mutant are only loosely attached.\u0000 In Streptococcus mutans YajC has been identified in complex with proteins of two cotranslational-membrane-protein-insertion pathways; the Signal-Recognition-Particle (SRP)-SecYEG-YajC-YidC1 and the SRP-YajC-YidC2 pathway, but its function is unknown. In S. mutans mutation of yidC1 and yidC2 resulted in impaired protein insertion in the cell membrane and secretion in the supernatant.\u0000 The E. faecium genome contains all homologous genes encoding for the cotranslational-membrane-protein-insertion pathways. By combining the studies in S. mutans and E. faecium, we propose that YajC is involved in the stabilization of the SRP-SecYEG-YajC-YidC1 and SRP-YajC-Yid2 pathway or plays a role in retaining proteins for proper docking to the YidC insertases for translocation in and over the membrane.","PeriodicalId":502482,"journal":{"name":"FEMS Microbes","volume":"81 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141123119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Short-term pectin-enriched smoothie consumption has beneficial effects on the gut microbiota of low-fiber consumers 短期食用富含果胶的冰沙对低纤维消费者的肠道微生物群有益

FEMS Microbes Pub Date : 2024-02-02 DOI: 10.1093/femsmc/xtae001

Susan Pihelgas, Kristel Ehala-Aleksejev, R. Kuldjärv, Ann Jõeleht, Jekaterina Kazantseva, K. Adamberg

引用次数: 0

Short-term pectin-enriched smoothie consumption has beneficial effects on the gut microbiota of low-fiber consumers 短期食用富含果胶的冰沙对低纤维消费者的肠道微生物群有益

FEMS Microbes Pub Date : 2024-02-02 DOI: 10.1093/femsmc/xtae001

Susan Pihelgas, Kristel Ehala-Aleksejev, R. Kuldjärv, Ann Jõeleht, Jekaterina Kazantseva, K. Adamberg

引用次数: 0