Nihon hoigaku zasshi = The Japanese journal of legal medicine最新文献

筛选
英文 中文
[Studies on distribution of H type 1-H type 4 antigens of ABO system and on FUT2 polymorphism]. [关于 ABO 系统 H 型 1-H 型 4 抗原分布和 FUT2 多态性的研究]。
H Kimura
{"title":"[Studies on distribution of H type 1-H type 4 antigens of ABO system and on FUT2 polymorphism].","authors":"H Kimura","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>I have examined the immunohistochemical distribution of H type 1-H type 4 antigens of the ABO system in human submandibular gland using either of the three anti-H monoclonal antibodies specific for H type 1, H type 2 and H type 3/4. I have clearly identified cell types expressing H type 1, H type 2 and H type 3/4: H type 1 in mucous cells and duct cells, H type 2 in duct cells, and H type 3/4 in serous cells of the submandibular gland. The expression of H type 1 and H type 3/4 in the human submandibular gland is regulated by the Se enzyme. The FUT2 encodes Secretor type alpha(1,2) fucosyltransferase (Se enzyme), which regulates the expression of ABH antigens in the gastrointestinal tract and secretions. Molecular analysis of the FUT2 polymorphism of various populations have indicated the ethnic specificity of null alleles: the null allele se428 is a common Se-enzyme deficient allele in Africans and Caucasians but does not occur in Asians, whereas the null allele se357,385 is specific to Asians. The gene frequency of se428 or se357,385 is about 0.5 in each respective population. Why the se428 is absent in Asians is of interest.</p>","PeriodicalId":502116,"journal":{"name":"Nihon hoigaku zasshi = The Japanese journal of legal medicine","volume":"54 3","pages":"315-23"},"PeriodicalIF":0.0,"publicationDate":"2000-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138809758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信