Isma Rachmawati, Raden Yohana, Bambang Amam, Yenni Zuhairini
{"title":"REDUCED BODY MASS INDEX BUT NOT FAT MASS IN ANTHRACYCLINE-BASED CHEMOTHERAPY OF LOCALLY ADVANCED BREAST CANCER PATIENTS","authors":"Isma Rachmawati, Raden Yohana, Bambang Amam, Yenni Zuhairini","doi":"10.54773/ijcnp.v6i1.174","DOIUrl":"https://doi.org/10.54773/ijcnp.v6i1.174","url":null,"abstract":"Background: Breast cancer is a cancer disease with the highest proportion of new cases and the proportion of deaths it causes is quite high at 6.9%. Cancer patients who use anthracycline-based chemotherapy experience loss of body weight, muscle, body cell mass, distribution of extracellular fluid expansion and reduced intracellular air. This study was to determine the change of the Body Mass index (BMI) and body composition of patients with locally advanced breast cancer (stage IIIA, IIIB and IIIC) who had undergone anthracycline-based chemotherapy.Methods: This anthracycline-based observational analytical study of pre and post chemotherapy was conducted with a cross-sectional approach. Subjects were measured height by microtoise; weight, body composition, daily calorie intake (DCI) and basal metabolic rate (BMR) as measured by Bioelectrical Impendance Analysis (BIA).Results: 47 locally advanced breast cancer patients underwent anthracycline-based chemotherapy. Based on the Wilcoxon statistical test, 6 variables with a 95% confidence level (p<0.05) showed a decrease in the value 5 variables, namely BMI, total body water (TBW), visceral fat, skeletal muscle mass and skeletal bone mass. Meanwhile, body fat showed a p value=0.224. The changes of variable confounding, DCI decrease (p=0.004), but BMR increase not significantly (p=0.795).Conclusion: There is an effect of chemotherapy on nutritional status of BMI, TBW, visceral fat, skeletal muscle mass and bone mass in patients with locally advanced breast cancer who underwent anthracycline-based chemotherapy, which may the result of the calorie intake decreased, but not on body fat","PeriodicalId":500454,"journal":{"name":"IJCNP (Indonesian Journal of Clinical Nutrition Physician)","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136341997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"HUBUNGAN PHASE ANGLE DENGAN TINGKAT KEPARAHAN INFARK MIOKARD","authors":"Rosa Kristiansen, None Niken Puruhita, None Febe Christianto, None Hertanto Wahyu Subagio, None Enny Probosari","doi":"10.54773/ijcnp.v6i1.156","DOIUrl":"https://doi.org/10.54773/ijcnp.v6i1.156","url":null,"abstract":"Latar belakang : Phase angle (PhA) yang merupakan indikator integritas seluler mungkin berhubungan dengan tingkat keparahan IM yang tercermin dari penanda cedera miosit yaitu kadar troponin.
 Tujuan : Menganalisis hubungan PhA dengan tingkat keparahan IM.
 Metode : Penelitian observasional, melibatkan 40 subjek dengan IM yang memenuhi kriteria inklusi dan eksklusi. Tingkat keparahan IM diukur dari kadar troponin I, PhA didapatkan dari bioelectrical impedance analysis, dan data komorbid diambil dari rekam medis pasien. Uji hipotesis menggunakan analisis bivariat untuk melihat hubungan phase angle dan beberapa komorbid dengan tingkat keparahan IM.
 Hasil : Mayoritas subyek penelitian berjenis kelamin laki-laki (82,5%), rerata usia 56,1 tahun, dan rerata IMT 25,56 kg/m2. Dislipidemia merupakan jenis komorbid yang paling banyak diderita (92,5%) dan 62,5% subyek penelitian memiliki 2 atau lebih komorbid. Hasil analisis bivariat PhA, jenis komorbid, jumlah komorbid, usia, IMT, dan jenis kelamin terhadap kadar troponin I adalah tidak signifikan (p>0,05).
 Kesimpulan : PhA, diabetes, hipertensi, dislipidemia, jumlah komorbid, usia, IMT, dan jenis kelamin tidak berhubungan dengan tingkat keparahan IM.
 Kata kunci : BIA, komorbid kardiovaskular, phase angle, tingkat keparahan infark miokard","PeriodicalId":500454,"journal":{"name":"IJCNP (Indonesian Journal of Clinical Nutrition Physician)","volume":"127 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136130975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"EFFECTIVENESS OF PROBIOTIC SUPPLEMENT ON HELICOBACTER PYLORI INFECTION ERADICATION IN GASTRIC ULCERS","authors":"None Sulistyanti Dian Rachmawati, Wiji Lestari","doi":"10.54773/ijcnp.v6i1.114","DOIUrl":"https://doi.org/10.54773/ijcnp.v6i1.114","url":null,"abstract":"Background: Helicobacter pylori colonizes the gastric mucosa in 50% of the human population. H. pylori infection causes several upper gastrointestinal tract diseases such as chronic gastritis, peptic ulcer, duodenal ulcer, and gastric cancer. H. pylori is also associated with a high risk of developing gastric adenocarcinoma. The World Health Organization classifies H. pylori infection as a class 1 carcinogen. Giving probiotics may improve the immune system and suppress the effects of pathogens. However, mixed results were obtained from the use of various kinds of bacteria and fungi as probiotics.
 Objective: To determine the effectiveness of probiotic supplementation against the eradication of Helicobacter pylori infection in gastric ulcers.
 Conclusion: The effectiveness uses of probiotics to eradicate H. pylori has not been proven. It will take clinical trials with a sufficient number of subjects and certain probiotic strains to be able to determine the type of strain, dosage, duration of use, and side effects that can be caused.","PeriodicalId":500454,"journal":{"name":"IJCNP (Indonesian Journal of Clinical Nutrition Physician)","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135827904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anastasia Hayuningtyas, None Lady Dhita Alfara, None Tjandraningrum, Victor Tambunan, Lukman Halim, Meilani Kumala, Johana Titus
{"title":"PROFIL ANTROPOMETRIK, VITAMIN D, B12, FOLAT, DAN FERITIN PASIEN OBES PRABEDAH BARIATRIK DI POLIKLINIK GIZI RUMAH SAKIT SUMBER WARAS","authors":"Anastasia Hayuningtyas, None Lady Dhita Alfara, None Tjandraningrum, Victor Tambunan, Lukman Halim, Meilani Kumala, Johana Titus","doi":"10.54773/ijcnp.v6i1.183","DOIUrl":"https://doi.org/10.54773/ijcnp.v6i1.183","url":null,"abstract":"Obese patients, especially patients with severe obesity and requiring bariatric surgery, have a high prevalence of nutrient deficiencies. This study aims to determine some of the basic characteristics of patients undergoing bariatric surgery so that they can be used as supporting data for post-bariatric surgery nutrition medical therapy, particularly in the provision of food sources and micronutrient supplementation which can be deficient due to anatomic and physiological alterations after the surgery. The study was conducted on 55 preoperative bariatric patients by assessing age, gender, and degree of obesity based on body mass index (BMI), serum vitamin D and B12 levels, erythrocyte folic acid, and serum ferritin of subjects. The study is descriptive with a cross-sectional design. Subjects were taken by consecutive sampling. The results showed that the mean age of preoperative bariatric patients was 36 ± 7.1 years; most (85.5%) were women. Most subjects (34.5%) had BMI of 35–39.9 kg/m2. Vitamin D deficiency was present in most (75.6%) of the study subjects, but most had serum vitamin B12 levels, erythrocyte folic acid levels, and serum ferritin levels within normal limits. This study shows that the basic profile of patients undergoing bariatric surgery is primarily late adults, classified as severe obese and having vitamin D deficiency.
 Keywords: Obesity, Prebariatric, Serum Vitamin D, Serum Vitamin B12, Erythrocyte Folic Acid, and Serum Ferritin.","PeriodicalId":500454,"journal":{"name":"IJCNP (Indonesian Journal of Clinical Nutrition Physician)","volume":"158 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135827111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"SUPLEMENTASI ASAM FOLAT PRAKONSEPSI DALAM PENCEGAHAN BIBIR SUMBING : EVIDENCE - BASED CASE REPORT","authors":"Amelia Jessica, None Nurul Ratna Mutu Manikam","doi":"10.54773/ijcnp.v6i1.117","DOIUrl":"https://doi.org/10.54773/ijcnp.v6i1.117","url":null,"abstract":"Bibir sumbing merupakan kelainan bawaan yang sering dijumpai pada bayi baru lahir, terutama di negara berkembang. Faktor risikonya antara lain paparan terhadap rokok dan bahan kimia, konsumsi alkohol, serta asupan mikronutrien yang tidak memadai selama kehamilan. Dosis suplementasi asam folat yang lebih tinggi pada masa prakonsepsi berhubungan dengan penurunan risiko bibir sumbing. Tujuan: Mengetahui hubungan antara suplementasi asam folat prakonsepsi dengan risiko terjadinya bibir sumbing. Metode: Pencarian literatur dilakukan dengan advanced searching pada Pubmed, Cochrane Library, Scopus, dan ProQuest dengan kriteria eligibilitas yang ditentukan oleh penulis. Hasil: Studi systematic review-meta analisis oleh Jayarajan, et al. (2019) menjelaskan bahwa terdapat hubungan kuat antara suplementasi asam folat dosis tinggi dengan bibir sumbing. Studi kasus-kontrol yang menilai hubungan suplementasi asam folat prakonsepsi dengan penurunan risiko bibir sumbing dilakukan oleh 2 peneliti. Penelitian Xu W, et al. (2021) menjelaskan bahwa suplementasi asam folat prakonsepsi menurunkan risiko bibir sumbing (aOR = 0,52, 95% CI 0,30-0,90), sedangkan penelitian Mendonca VJ, et al. (2019) menjelaskan bahwa untuk mendapatkan efek samping pada 1 pasien diperlukan 71 pasien dengan suplementasi asam folat selama 1 tahun. Kesimpulan: Berdasarkan dua penelitian didapatkan hasil bahwa suplementasi asam folat prakonsepsi dapat menurunkan risiko bibir sumbing, namun diperlukan penelitian lebih lanjut.","PeriodicalId":500454,"journal":{"name":"IJCNP (Indonesian Journal of Clinical Nutrition Physician)","volume":"161 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135827901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}