Eye Banking and Corneal Transplantation最新文献

{"title":"Eye Bank Association of America Medical Standards 2023","authors":"","doi":"10.1097/ebct.0000000000000027","DOIUrl":"https://doi.org/10.1097/ebct.0000000000000027","url":null,"abstract":"","PeriodicalId":500335,"journal":{"name":"Eye Banking and Corneal Transplantation","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141394162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coniochaeta hoffmannii and mutabilis Invasive Fungal Keratitis: A Case Series and Literature Review","authors":"Roma B. Pegany, Reid L. Wilson, Hillary C. Stiefel, Daniel M. Albert, Winston D. Chamberlain, Travis K. Redd","doi":"10.1097/ebct.0000000000000024","DOIUrl":"https://doi.org/10.1097/ebct.0000000000000024","url":null,"abstract":"\u0000 \u0000 To describe 2 Coniochaeta species (Coniochaeta hoffmannii and Coniochaeta mutabilis) as rare causes of invasive fungal keratitis resulting in enucleations and to provide a review of ocular infections caused by the genus Coniochaeta and underscore changes to its classification over the past 3 decades, which may clarify previous reports with outdated nomenclature.\u0000 \u0000 \u0000 \u0000 This is a small case series from a single academic institution (Casey Eye Institute) with a summary of the literature.\u0000 \u0000 \u0000 \u0000 The first case describes a 53-year-old man who had an indolent but persistent anterior chamber reaction after repair of a penetrating nail injury. Cultures from a second penetrating keratoplasty identified C. hoffmannii, which was determined through phenotypic characterization and DNA sequencing. Despite surgical management, cultures were persistently positive for C. hoffmannii. Two years post-injury, he developed a funnel retinal detachment with proliferative vitreoretinopathy and elected for enucleation. The second case describes a 54-year-old woman with poor contact lens hygiene with a presumed filamentous fungal keratitis that remained refractory to topical natamycin. Broad-range polymerase chain reaction of an anterior chamber aspirate identified C. mutabilis. Therapeutic keratoplasty was performed for worsening infection; however, because of intractable pain, she elected for enucleation. Pathology from the enucleation specimen demonstrated persistent, but sparse, fungal elements.\u0000 \u0000 \u0000 \u0000 This is the first case series characterizing ocular infections caused by Coniochaeta, a rare cause of invasive fungal keratitis resulting in devastating outcomes for our patients. Identification of Coniochaeta was initially difficult by traditional culturing techniques, and subsequent molecular diagnostic testing proved useful in detection. Our review of ocular Coniochaeta clarifies previous reports with outdated nomenclature.\u0000","PeriodicalId":500335,"journal":{"name":"Eye Banking and Corneal Transplantation","volume":"2013 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140416425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification and Management of a Central Type 2 Big Bubble in Deep Anterior Lamellar Keratoplasty","authors":"Justin M. Wileman, Marianne O. Price, Francis W. Price","doi":"10.1097/ebct.0000000000000018","DOIUrl":"https://doi.org/10.1097/ebct.0000000000000018","url":null,"abstract":"Purpose: The purpose of this study was to document a case of central type 2 bubble formation during deep anterior lamellar keratoplasty and discuss its intraoperative management. Methods: A rare case of central type 2 bubble formation with no peripheral extension beyond the trephination mark was documented with operative video and concurrent intraoperative optical coherence tomography imaging. Results: The type 2 bubble was decompressed with a needle intraoperatively, and deep anterior lamellar keratoplasty was successfully performed without perforation of Descemet membrane. Conclusions: Identifying formation of a type 2 bubble during deep anterior lamellar keratoplasty is crucial in avoiding perforation of Descemet membrane. This case shows that the behavior of type 2 bubbles can be different than what has been widely reported. It is hoped that this will aid the surgeon in identifying a type 2 bubble and in properly managing it intraoperatively.","PeriodicalId":500335,"journal":{"name":"Eye Banking and Corneal Transplantation","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136013455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Double Povidone-Iodine Wash on Rate of Positive Donor Corneoscleral Rim Cultures: A 7-Year Eye Bank Analysis","authors":"Tu M. Tran, Daniel Fraser, Christina L. Gillmor, Edwin Roberts, Patricia Dahl, Alessandro Meduri, Stephen C. Kaufman","doi":"10.1097/ebct.0000000000000014","DOIUrl":"https://doi.org/10.1097/ebct.0000000000000014","url":null,"abstract":"Introduction: Starting October 2018, the Eye Bank Association of America modified the national standard protocol to incorporate a double povidone-iodine (P-I) wash at the time of procurement. Purpose: To determine if double P-I wash resulted in a reduced rate of positive donor rim cultures. Methods: A comprehensive database review was performed on consecutive corneoscleral tissue handled by The Eye-Bank for Sight Restoration (New York, NY) from January 2015 to December 2021. The primary outcome was the rate of positive corneoscleral rim cultures for bacteria or fungus. Secondary outcomes included rate of postoperative infection (eg, keratitis or endophthalmitis). For analysis, statistical significance was determined as P < 0.05. Results: Of 6079 corneal transplants performed, 3491 were done before implementation of double P-I wash with a total culture positive rate of 0.43%. There were 2588 corneal transplants performed after implementation of double P-I wash with a total positive culture rate of 0.23%, which is a significant reduction (Poisson regression incidence rate ratio [IRR] 0.35 [95% CI 0.089–0.61], P = 0.007). The most common organisms preimplementation were Candida species (46.7% of culture-positive rims), whereas no candida species were isolated postimplementation (logit regression, P = 0.034). Cutibacterium acnes culture positivity rate increased postimplementation to 50.0% versus 13.3% preimplementation (logit regression, P = 0.116). The rate of postoperative infection was 1.55% and 1.00% for preimplementation and postimplementation, respectively (IRR 0.30 [95% CI, 0.18–0.50], P < 0.001). Conclusions: The use of double P-I wash was associated with a decrease in the rate of positive corneoscleral donor rim cultures and a decrease in the rate of postoperative infection.","PeriodicalId":500335,"journal":{"name":"Eye Banking and Corneal Transplantation","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135346965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}