Perspectivas em Medicina Legal e Perícias Médicas最新文献

METHOD VALIDATION FOR QUANTIFICATION OF CARBAMAZEPINE IN FINGERPRINTS DEPOSITED ON GLASS COVER SLIPS 玻片指纹图谱中卡马西平含量测定方法验证

Perspectivas em Medicina Legal e Perícias Médicas Pub Date : 2023-01-01 DOI: 10.47005/230625

Isadora Müller, Lilian Lizot, Rafael Linden

{"title":"METHOD VALIDATION FOR QUANTIFICATION OF CARBAMAZEPINE IN FINGERPRINTS DEPOSITED ON GLASS COVER SLIPS","authors":"Isadora Müller, Lilian Lizot, Rafael Linden","doi":"10.47005/230625","DOIUrl":"https://doi.org/10.47005/230625","url":null,"abstract":"INTRODUCTION: About 38 million people are exposed to carbamazepine per year for the treatment of epilepsy. The drug is on the WHO essential list. The treatment for epilepsy happens in a prophylactic way, to provide the patient with a better life condition. Therefore, in addition to the choice of medication and the dose required for everyone, adherence to therapy is also of great importance in the functioning of the treatment. Fingerprint is widely used in the forensic area, this matrix is also appearing in the toxicological and clinical area, to find out if the individual has ingested a substance. MATERIAL AND METHOD: A method was validated in High Performance Liquid Chromatography coupled to Mass Spectrometry, following the validation parameters of the Food and Drug Administration for the quantification of carbamazepine (CBZ) in fingerprints. RESULTS: The method demonstrated high sensitivity for detecting CBZ in fingerprint samples. The detection limit of the method was 0.05 ng digital-1 for CBZ. The intra-assay precision ranged from 3.58 to 7.90%. The inter-assay precision was 2.16 to 5.79% for CBZ. The accuracy presented by the method ranged from 95.02 to 102.76%. DISCUSSION: Liquid chromatography conditions play a key role in achieving fast and effective component separation and ionization. CONCLUSION: Thus, a simple and sensitive method is being validated for CBZ quantification in fingerprint samples deposited on glass slides.","PeriodicalId":497438,"journal":{"name":"Perspectivas em Medicina Legal e Perícias Médicas","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135952990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

INCAPACITY FOR WORK DUE TO MENTAL AND BEHAVIORAL DISORDERS IN BRAZILIAN SOCIAL SECURITY: A TEMPORAL ANALYSIS 巴西社会保障中由于精神和行为障碍而丧失工作能力:一个时间分析

Perspectivas em Medicina Legal e Perícias Médicas Pub Date : 2023-01-01 DOI: 10.47005/230623

Brunna Sá, Rebeca Gomes, Rosa Dantas

引用次数: 0

RELATIONSHIP BETWEEN THE COVID-19 PANDEMIC AND THE RESULTS OF SEXUAL VIOLENCE – BEFORE AND DURING 2019冠状病毒病大流行之前和期间与性暴力结果之间的关系

Perspectivas em Medicina Legal e Perícias Médicas Pub Date : 2023-01-01 DOI: 10.47005/230724

Guilherme Macedo, Maria Luisa Duarte

{"title":"RELATIONSHIP BETWEEN THE COVID-19 PANDEMIC AND THE RESULTS OF SEXUAL VIOLENCE – BEFORE AND DURING","authors":"Guilherme Macedo, Maria Luisa Duarte","doi":"10.47005/230724","DOIUrl":"https://doi.org/10.47005/230724","url":null,"abstract":"INTRODUCTION: Sexual violence is rooted in society and has several consequences that affect individual and collective health. This crime is linked to interpersonal relationships and the daily life of the population, which were clearly modified during the covid-19 pandemic. OBJECTIVES: To analyze the reports of sexual violence in the archives of Instituto Médico Legal Estácio de Lima, and Hospital da Mulher Dr. Nise da Silveira, both in Maceió/AL, corresponding to the pre-pandemic period (2018 and 2019) and the pandemic period (2020 and 2021), seeking a possible change in the profile of this crime. MATERIAL AND METHOD: This is a documentary, epidemiological, descriptive and analytical study, using sampling. A total of 2,152 reports from the IML Estácio de Lima file were analyzed between the years 2018 to 2021. RESULTS: It was found that the prevalent gender was female, but there was an increase in the percentage of males of 4.38% in the pandemic period. The predominant age group was 11 to 20 years old. In the years 2018, 2019 and 2021, those accused of committing the crime were predominantly known people, and in 2021, family members represented the majority of the aggressors. DISCUSSION: The profile of cases of sexual violence has changed markedly during the covid-19 pandemic, probably due to the restrictive measures imposed to reduce the spread of the virus in society. CONCLUSION: Human activities, interpersonal relationships and, consequently, the profile of cases of sexual violence, were clearly altered due to the covid-19 pandemic. Keywords: Covid-19; Sexual violence; Medico-legal expertise.","PeriodicalId":497438,"journal":{"name":"Perspectivas em Medicina Legal e Perícias Médicas","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135210931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

AN ATYPICAL HOMICIDE CAUSED BY CUT-THROATS IN BRAZIL 这是一起发生在巴西的非典型杀人案

Perspectivas em Medicina Legal e Perícias Médicas Pub Date : 2023-01-01 DOI: 10.47005/230621

Conrado Pessoa, Nathália Loubet, Ana Falcão, Murilo Valente-Aguiar

引用次数: 0

RELATIONSHIP BETWEEN THE COVID-19 PANDEMIC AND THE RESULTS OF SEXUAL VIOLENCE – BEFORE AND DURING. 2019冠状病毒病大流行之前和期间与性暴力结果之间的关系

Perspectivas em Medicina Legal e Perícias Médicas Pub Date : 2023-01-01 DOI: 10.47005/230624

Guilherme Macedo, Maria Duarte

{"title":"RELATIONSHIP BETWEEN THE COVID-19 PANDEMIC AND THE RESULTS OF SEXUAL VIOLENCE – BEFORE AND DURING.","authors":"Guilherme Macedo, Maria Duarte","doi":"10.47005/230624","DOIUrl":"https://doi.org/10.47005/230624","url":null,"abstract":"INTRODUCTION: Sexual violence is rooted in society and has several consequences that affect individual and collective health. This crime is linked to interpersonal relationships and the daily life of the population, which were clearly modified during the covid-19 pandemic. OBJECTIVES: To analyze the reports of sexual violence in the archives of Instituto Médico Legal Estácio de Lima, and Hospital da Mulher Dr. Nise da Silveira, both in Maceió/AL, corresponding to the pre-pandemic period (2018 and 2019) and the pandemic period (2020 and 2021), seeking a possible change in the profile of this crime. MATERIAL AND METHOD: This is a documentary, epidemiological, descriptive and analytical study, using sampling. A total of 2,152 reports from the IML Estácio de Lima file were analyzed between the years 2018 to 2021. RESULTS: It was found that the prevalent gender was female, but there was an increase in the percentage of males of 4.38% in the pandemic period. The predominant age group was 11 to 20 years old. In the years 2018, 2019 and 2021, those accused of committing the crime were predominantly known people, and in 2021, family members represented the majority of the aggressors. DISCUSSION: The profile of cases of sexual violence has changed markedly during the covid-19 pandemic, probably due to the restrictive measures imposed to reduce the spread of the virus in society. CONCLUSION: Human activities, interpersonal relationships and, consequently, the profile of cases of sexual violence, were clearly altered due to the covid-19 pandemic.","PeriodicalId":497438,"journal":{"name":"Perspectivas em Medicina Legal e Perícias Médicas","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135952987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PROCEDURAL ERROR IN AUTOPSIES POST HANGING AND STRANGLING IN A MEDICO-LEGAL INSTITUTE IN ALAGOAS, BRAZIL, IN 2018 AND 2019 2018年和2019年，在巴西阿拉戈斯的一家法医研究所，尸体解剖中的程序错误导致了上吊和勒死

Perspectivas em Medicina Legal e Perícias Médicas Pub Date : 2023-01-01 DOI: 10.47005/230622

Gabriel Maia, Pedro Silva, Hermann Gusmão, Alberto Filho, Thierry Reis, Daniele Bezerra, Gerson Pereira

引用次数: 0

METHOD VALIDATION FOR QUANTIFICATION OF CARBAMAZEPINE IN FINGERPRINTS DEPOSITED ON GLASS COVER SLIPS 玻片指纹图谱中卡马西平含量测定方法验证

Perspectivas em Medicina Legal e Perícias Médicas Pub Date : 2023-01-01 DOI: 10.47005/230725

Isadora Muller, Lilian Lizot, Rafael Linden

{"title":"METHOD VALIDATION FOR QUANTIFICATION OF CARBAMAZEPINE IN FINGERPRINTS DEPOSITED ON GLASS COVER SLIPS","authors":"Isadora Muller, Lilian Lizot, Rafael Linden","doi":"10.47005/230725","DOIUrl":"https://doi.org/10.47005/230725","url":null,"abstract":"INTRODUCTION: About 38 million people are exposed to carbamazepine per year for the treatment of epilepsy. The drug is on the WHO essential list. The treatment for epilepsy happens in a prophylactic way, to provide the patient with a better life condition. Therefore, in addition to the choice of medication and the dose required for everyone, adherence to therapy is also of great importance in the functioning of the treatment. Fingerprint is widely used in the forensic area, this matrix is also appearing in the toxicological and clinical area, to find out if the individual has ingested a substance. MATERIAL AND METHOD: A method was validated in High Performance Liquid Chromatography coupled to Mass Spectrometry, following the validation parameters of the Food and Drug Administration for the quantification of carbamazepine (CBZ) in fingerprints. RESULTS: The method demonstrated high sensitivity for detecting CBZ in fingerprint samples. The detection limit of the method was 0.05 ng digital-1 for CBZ. The intra-assay precision ranged from 3.58 to 7.90%. The inter-assay precision was 2.16 to 5.79% for CBZ. The accuracy presented by the method ranged from 95.02 to 102.76%. DISCUSSION: Liquid chromatography conditions play a key role in achieving fast and effective component separation and ionization. CONCLUSION: Thus, a simple and sensitive method is being validated for CBZ quantification in fingerprint samples deposited on glass slides. Keywords: Carbamazepine, Fingerprints, Quantification.","PeriodicalId":497438,"journal":{"name":"Perspectivas em Medicina Legal e Perícias Médicas","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135211174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ANALYSIS OF SEXUAL CRIMES COMMITTED IN THE STATE OF CEARÁ BETWEEN JANUARY 2020 AND JULY 2022 2020年1月至2022年7月cearÁ州性犯罪分析

Perspectivas em Medicina Legal e Perícias Médicas Pub Date : 2023-01-01 DOI: 10.47005/230626

Carolina Farias, Ana Teixeira, Cristina Linheiro, Rebeca Mourão, Silvia Benevides, Victor Alencar

引用次数: 0

ANALYSIS OF SEXUAL CRIMES COMMITTED IN THE STATE OF CEARÁ BETWEEN JANUARY 2020 AND JULY 2022 2020年1月至2022年7月cearÁ州性犯罪分析

Perspectivas em Medicina Legal e Perícias Médicas Pub Date : 2023-01-01 DOI: 10.47005/230726

Carolina de Paiva Farias, Ana Teixeira, Cristina Linheiro, Rebeca Mourão, Silvia Benavides, Victor Alencar

{"title":"ANALYSIS OF SEXUAL CRIMES COMMITTED IN THE STATE OF CEARÁ BETWEEN JANUARY 2020 AND JULY 2022","authors":"Carolina de Paiva Farias, Ana Teixeira, Cristina Linheiro, Rebeca Mourão, Silvia Benavides, Victor Alencar","doi":"10.47005/230726","DOIUrl":"https://doi.org/10.47005/230726","url":null,"abstract":"INTRODUCTION: in Ceará, children and adolescents represent the main victims of sexual crimes. Due to this, the objective of this work is to analyze this violence and ensure wide dissemination of data related to public security in the state of Ceará. MATERIAL AND METHOD: this is a descriptive and quantitative epidemiological study carried out using secondary data published by the Secretary of Public Security and Social Defense of Ceará (SSPDS/CE) through the Statistics and Geoprocessing Management (GEESP/SUPESP) on crime and sexual violence in Ceará from January 2020 to July 2022. RESULTS: 4,692 cases were reported during the study period, with an average monthly crime rate of 154.91 crimes per month in 2020, 162.16 crimes per month in 2021, and 147.83 crimes per month in 2022. DISCUSSION: the results presented in this study, although the year 2022 is not finalized, show higher rates of sexual crime when compared to the months from March to June of previous years. The increase in these crimes could be related to the return of post-pandemic activities, the political period, and other events. CONCLUSION: from March to June 2022, an increase in sexual crimes was observed, and, in view of this, there is a need for public bodies responsible for security to seek means that can prevent these events.","PeriodicalId":497438,"journal":{"name":"Perspectivas em Medicina Legal e Perícias Médicas","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134882492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0