Current nutraceuticals最新文献

"Diabetes Management: Herbal Remedies and Emerging Therapies "糖尿病管理：草药疗法和新兴疗法

Current nutraceuticals Pub Date : 2024-05-10 DOI: 10.2174/0126659786283493240415155919

Pratik Kumar Vishwakarma, Ankita Mohrana, Snigdha Rani Behera, Priyabati Choudhury, Sonali Jayronia, Shivendra Mani Tripathi

{"title":"\"Diabetes Management: Herbal Remedies and Emerging Therapies","authors":"Pratik Kumar Vishwakarma, Ankita Mohrana, Snigdha Rani Behera, Priyabati Choudhury, Sonali Jayronia, Shivendra Mani Tripathi","doi":"10.2174/0126659786283493240415155919","DOIUrl":"https://doi.org/10.2174/0126659786283493240415155919","url":null,"abstract":"\u0000\u0000Diabetes is a chronic disease affecting millions worldwide, characterized by inadequate insulin production or malfunctioning insulin action, leading to elevated blood sugar levels.\u0000Its prevalence is escalating globally, with estimates projecting a rise from 2.8% to over 5.4% of\u0000the world's population by 2025. In India, diabetes poses a significant health challenge, especially\u0000in urban areas. While conventional medications are widely available, herbal remedies have\u0000gained popularity due to their potential for fewer side effects and lower costs. Herbal remedies\u0000have been employed for centuries in diabetes management and have been extensively studied for\u0000their blood sugar regulatory properties. Prominent herbs studied for their potential to manage\u0000diabetes include gymnema, cinnamon, fenugreek, and bitter melon. These herbs are believed to\u0000enhance insulin sensitivity, reduce glucose absorption in the intestines, and improve glucose metabolism. This review highlights emerging alternative treatment options, such as stem cell therapy and gene therapy, in the field of diabetes management. Stem cell therapy aims to regenerate\u0000insulin-producing cells or enhance their function, while gene therapy targets the underlying genetic factors contributing to diabetes. These innovative approaches hold promise for more effective and personalized treatments in the future. It is essential to emphasize that any diabetes\u0000treatment or remedy should be discussed with a healthcare professional. Diabetes management\u0000requires a personalized approach based on individual needs and medical history. The integration\u0000of herbal remedies and alternative treatment options into conventional diabetes management\u0000warrants further research to determine their efficacy, safety, and potential for widespread implementation\u0000","PeriodicalId":497255,"journal":{"name":"Current nutraceuticals","volume":" 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140993289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biological Potential and Therapeutic Effectiveness of Sotetsuflavone in Medicine: A Natural Biflavonoids from Cycas Revolute against Human Disorders 苏铁黄酮在医学中的生物潜力和疗效：从苏铁中提取的天然双黄酮对人类疾病的疗效

Current nutraceuticals Pub Date : 2024-01-17 DOI: 10.2174/0126659786265835231224172204

D. Patel

引用次数: 0

Abutilon Indicum: Bioactive Compounds and Diverse TherapeuticApplications 苘麻：生物活性化合物和多种治疗应用

Current nutraceuticals Pub Date : 2024-01-17 DOI: 10.2174/0126659786272937240104222224

Shobhit Prakash Srivastava, Swati Dikshit, Ankita Moharana, Neha Chaturvedi, Saurabh Sharma, Preeti Verma

{"title":"Abutilon Indicum: Bioactive Compounds and Diverse Therapeutic\u0000Applications","authors":"Shobhit Prakash Srivastava, Swati Dikshit, Ankita Moharana, Neha Chaturvedi, Saurabh Sharma, Preeti Verma","doi":"10.2174/0126659786272937240104222224","DOIUrl":"https://doi.org/10.2174/0126659786272937240104222224","url":null,"abstract":"\u0000\u0000A large variety of secondary metabolites are found in medicinal plants, and the majority\u0000are significant in medicine. One of the well-known plant species used to cure a wide range of human\u0000illnesses is Abutilon indicum. The plant Abutilon indicum has a wide range of therapeutic uses, and\u0000its varied parts have been employed to cure a wide range of ailments. Numerous bioactive substances,\u0000such as polyphenols, flavonoids, alkaloids, saponins, tannins, and glycosides are present in\u0000the plant. Potent antioxidant, anti-inflammatory, antibacterial, hepatoprotective, hypoglycaemic, analgesic,\u0000sedative, and diuretic activities have been demonstrated in these compounds. Additionally,\u0000the plant has been shown to have cytoprotective properties and to guard against DNA damage\u0000brought on by oxidative stress. Future research is required to pinpoint the specific bioactive chemicals\u0000responsible for the pharmacological effects of Abutilon indicum and the molecular mechanisms\u0000underlying the plant's therapeutic uses. Overall, Abutilon indicum has demonstrated great therapeutic\u0000potential and deserves further study as a possible source of homeopathic treatments for various illnesses.\u0000The present study covers a summary of the phytochemical and ethnomedicinal applications\u0000of Abutilon Indicum that would further help in exploring the research in natural medicine.\u0000","PeriodicalId":497255,"journal":{"name":"Current nutraceuticals","volume":"57 41","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139527518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of Anti-Cancer Effects in Grapefruit-Based Drug Development:A Narrative Review 葡萄柚类药物开发中的抗癌效果分析：叙述性综述

Current nutraceuticals Pub Date : 2023-12-06 DOI: 10.2174/0126659786260551231127042822

J. K. Gupta, Kuldeep Singh, Shivendra Kumar, Girdhar Khandelwal

{"title":"Analysis of Anti-Cancer Effects in Grapefruit-Based Drug Development:\u0000A Narrative Review","authors":"J. K. Gupta, Kuldeep Singh, Shivendra Kumar, Girdhar Khandelwal","doi":"10.2174/0126659786260551231127042822","DOIUrl":"https://doi.org/10.2174/0126659786260551231127042822","url":null,"abstract":"\u0000\u0000Cancer remains a significant global health concern, and natural compounds found in\u0000fruits and vegetables have shown potential anti-cancer effects. Grapefruit (Citrus paradisi) has\u0000gained attention due to its rich phytochemical composition and biological activities, including\u0000anti-cancer properties. This narrative review analyzes the literature on grapefruit-based drug\u0000development and its potential as an adjunctive or alternative therapeutic strategy for cancer\u0000treatment. Grapefruit-derived compounds have been extensively studied for their anti-cancer\u0000effects, with preclinical studies showing promising outcomes in inhibiting cancer cell growth\u0000and proliferation. Compounds made from grapefruit also have anti-cancer effects. They do this\u0000in a number of ways, such as by affecting the cell cycle, apoptosis, angiogenesis, metastasis,\u0000and key signalling pathways. Petrified grapefruit compounds have potential synergistic effects\u0000with conventional chemotherapy drugs, enhancing cytotoxic effects while reducing adverse\u0000side effects. They have shown promising results in overcoming drug resistance, a major obstacle in cancer treatment. However, challenges such as bioavailability, drug interactions, and\u0000variability in compound composition remain. Overall, grapefruit-derived compounds possess\u0000significant anti-cancer properties and warrant further investigation for clinical application.\u0000","PeriodicalId":497255,"journal":{"name":"Current nutraceuticals","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138595195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Comprehensive Review on Peptic Ulcer 消化性溃疡综述

Current nutraceuticals Pub Date : 2023-12-06 DOI: 10.2174/0126659786247721231117110442

Rishabh Gaur, Mohit Sandhuja, Varsha Snehi, Akash Ved, K. Shukla, Arpita Singh, Devender Pathak, M. Kulshreshtha

引用次数: 0

A Narrative Review on Effects of Napier Grass Oxalate Accumulation on Ruminant Animals 牧草草酸盐积累对反刍动物影响的综述

Current nutraceuticals Pub Date : 2023-10-15 DOI: 10.2174/0126659786264552231006061951

Panir Choudhury, S. M. Jahangir Hossain, Shahrina Akter, Md. Tasmirul Islam, None Khadija-Tut-Tahira

{"title":"A Narrative Review on Effects of Napier Grass Oxalate Accumulation on Ruminant Animals","authors":"Panir Choudhury, S. M. Jahangir Hossain, Shahrina Akter, Md. Tasmirul Islam, None Khadija-Tut-Tahira","doi":"10.2174/0126659786264552231006061951","DOIUrl":"https://doi.org/10.2174/0126659786264552231006061951","url":null,"abstract":"Napier grass is a popular ruminant feed due to its nutritional value and ease of propaga-tion. Besides these promising characteristics, Napier grass poisoning has been reported in livestock, and oxalate has been identified as a primary toxin. Oxalate is an antinutrient content that prevents absorption of minerals from plants while grazing by animals. Less than 2.0% of ruminants' soluble oxalate of dry matter (DM) consumption is safe, while 0.5% is safe for non-ruminants. Oxalate buildup varies with nitrogen sources and dosages. This review discusses the impacts of external and internal elements, including fodder species/variety, fodder portions, seasonal change, nitrogen ferti-lization, clipping interval, and oxalate concentration on grazing animals and management measures to reduce fodder oxalate. However, further research is needed to understand how oxalate in different species interacts with grazing animals. For developing oxalate-free fodder genotypes, molecular techniques, including identification of CRISPR/Cas9, QTLs, and functional genomics, may be help-ful. Genomic methods to improve Napier grass employing precision phenotyping, genotyping, and molecular technology have also been discussed in this article. We have discussed the metabolic path-way, digestion in ruminant animals, factors affecting oxalate content, genetic and molecular diver-sity, oxalate impact and poisoning, disease to Napier grass and future prospects. This may be helpful for the researchers working on ruminant animals for their feeds and fodder.","PeriodicalId":497255,"journal":{"name":"Current nutraceuticals","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135759069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Standardization of Herbal Medicines and the Guidelines for the Standardization 中药标准化及标准化指南

Current nutraceuticals Pub Date : 2023-10-12 DOI: 10.2174/0126659786260672231002181650

Tejas Ahire, Seema Gosavi, Saurabh Sonawane, Riya Chaudhari, Pratiksha Bornare

{"title":"Standardization of Herbal Medicines and the Guidelines for the Standardization","authors":"Tejas Ahire, Seema Gosavi, Saurabh Sonawane, Riya Chaudhari, Pratiksha Bornare","doi":"10.2174/0126659786260672231002181650","DOIUrl":"https://doi.org/10.2174/0126659786260672231002181650","url":null,"abstract":"Abstract: The use of medicinal plants for their therapeutic benefits is immemorial, leading to their global acceptability. The pharmaceutical market is significantly influenced by medicinal plants and herbal preparations as a source for pharmaceutical manufacturing procedures. Over the past few decades, the mass production of herbal preparations at an industrial scale as well as the adulteration of raw material and final products have raised serious concerns over its safety, purity, and efficacy. Standardization of medicinal plants and their preparations as per the current WHO guidelines is of prime importance to overcome quality issues. The guidelines aim at the identification of potentially hazardous contaminants and assessing the quality of the herbal material by various qualitative and quantitative means. Various methodologies, techniques, and procedures are prescribed in the guidelines for maintaining the overall quality of the finished herbal product. However, due to a lack of research data and technical constraints many of the accepted limits in the guidelines are a reference and extrapolation of research done in food science. Standardization is a crucial part of the quality assurance program so as to set proper norms for the manufacture of quality products thus contributing to the benefit of mankind. The current review aims at highlighting various standardization parameters and guidelines for the same.","PeriodicalId":497255,"journal":{"name":"Current nutraceuticals","volume":"147 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136015144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biological Importance and Therapeutic Potential of Naturally Occurring Biflavonoid Isocryptomerin in Medicine 天然双黄酮类异cryptomerin在医学上的生物学重要性和治疗潜力

Current nutraceuticals Pub Date : 2023-10-05 DOI: 10.2174/2665978604666230915124113

Dinesh Kumar Patel

引用次数: 0