Cross current international journal of medical and biosciences最新文献

{"title":"Knowledge and Practice of Vector Control against Malaria by Mothers of Children Aged 06 to 59 Months Hospitalized for Severe Malaria in the Pediatric Department of the Reference Health Center of Commune I of Bamako","authors":"O. Coulibaly, Daouda Camara, Yacouba Sylla, Fatoumata Diakite, Amadou Landouré, Bakary Keita, C. Keita, Kadiatou Ba, B. Maiga, Oumar Coulibaly, Diakaridia Koné, Nouhoum Traore, Ousmane Diam","doi":"10.36344/ccijmb.2024.v06i01.006","DOIUrl":"https://doi.org/10.36344/ccijmb.2024.v06i01.006","url":null,"abstract":"Introduction: Severe malaria is a public health problem that causes a real socio-economic burden in developing countries. It is associated with high but avoidable mortality thanks to preventive and curative measures. Methodology: This is a descriptive and cross-sectional study with a prospective survey for the benefit of mothers of children aged 06 to 59 months hospitalized for serious malaria in the pediatric department of the Reference Health Center of Commune I of Bamako from October 2021 to September 2022. Results: In 12 months, 624 children were hospitalized, including 151 children aged 6 to 59 months suffering from severe malaria. The hospital frequency of severe malaria in this age group from 06 to 59 months was 24.2%. The average age of the mothers interviewed was 27.8 years with a range of 15 to 48 years. Mothers were educated in 84.1%, married in 98.7% and working as housewives in 81.5%. The reason for consulting children was fever (91.4%), anorexia (90.1%), prostration (79.5%). Mothers knew about impregnated mosquito nets and smoke coils as means of prevention against malaria at the same frequency of 99.3%, repellent creams 96.7%, and indoor spraying in 92.7%. In practice, they used smoke coils in 64.2%, repellent cream in 44.4% and mosquito nets impregnated with insecticide in 40.4%. Mothers attributed the cause of malaria to mosquito bites in 91.4%; They had readjusted the way sick children were fed by giving more food than usual (29.8%), splitting meals (21.8%) or using active feeding (14.6%). Most children had severe malaria, neurological form or anemic form at the same proportion of 37.1%. The assessment of the nutritional status of children revealed 18.5% acute malnutrition. The children had received conventional and traditional self-medication in 63.58 and 58.94% of cases respectively before admission. In children, a significant relationship was noted between severe anemic malaria and acute malnutrition (Fisher's exact test = 18.41; p = 0.01). ....","PeriodicalId":496559,"journal":{"name":"Cross current international journal of medical and biosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140457343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of the Hydromethanol Leaf Extract of Craterispermum schweinfurthi on Sperm Characteristics and Haematological Indices in Male Wistar Rats","authors":"Saronee F, Amadi J, Azosibe P","doi":"10.36344/ccijmb.2024.v06i01.005","DOIUrl":"https://doi.org/10.36344/ccijmb.2024.v06i01.005","url":null,"abstract":"Sexual and haematological abnormalities are on the increase, hence the need to identify possible ameliorative agents. The present study evaluates the effects of the hydromethanol leaf extract of Craterispermum schweinfurthi on sperm characteristics and haematological indices in male wistar rats. A total of 20 male wistar rats weighing between 100-250g were randomly divided into 4 groups of 5 rats each and treated as follows for 28days: Group A: Negative control: Group B, C and D received 250mg/kgbw, 500mg/kg bw and 750mg/kg bw of extract. On day 29, the rats were placed under chloroform anaesthesia and blood samples collected for the estimation of serum total white blood cell, red blood cell and platelet counts. Also, rats caudal epididymides were isolated for sperm characteristics estimation. Compared to Group A rats, significantly higher values of sperm count, active sperm, and population of normal sperm were observed amongst Groups B-D rats in a dose dependent manner (p<0.05). For sperm volume and viability, significant increases were observed amongst Group D rats only compared to Group A rats (p<0.05): Suggesting a possible greater potency of the extract at 750mg/kg body weight. Population of abnormal sperm, sluggish sperm and dead sperm were significantly decreased amongst Groups B-D rats compared to Group A rats (p<0.05). Similarly, a significant and dose dependent increase in total WBC, RBC and PLT counts following graded extract doses administration were observed amongst rats in B, C and D Groups compared to Group A rats: Demonstrating a possible blood boosting potentials of the extract in male wistar rats. The extract apparently exhibits potential beneficial effects on sperm characteristics and haematopoiesis in male wistar rats.","PeriodicalId":496559,"journal":{"name":"Cross current international journal of medical and biosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140461258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Psychosocial Risk Factors Associated with Depression in Older People in A Rural Community","authors":"Daniel Antonio Muñoz González, María Eugenia López Caamal, M. Figueroa, José Miguel Chin Chan","doi":"10.36344/ccijmb.2024.v06i01.004","DOIUrl":"https://doi.org/10.36344/ccijmb.2024.v06i01.004","url":null,"abstract":"Depression is a multifactorial disease that globally impacts all ages and sectors of the population. In this sense, it has become a public health problem, since it affects 280 million people in the world, according to information from the World Health Organization. Older adults represent 5.7% of the population that experiences this disease, with the moderate to severe stage being the one that most impacts their health, and, therefore, quality of life. For this reason, the objective of the research is to know the prevalence and psychosocial risk factors associated with depression in older people in the community of Santa Cruz, Hecelchakán, Campeche. The methodology used is with a quantitative approach because information was collected, based on the application of the Yesavage scale of geriatric depression, and the sociodemographic registry of 60 older adults of both sexes, in order to measure the percentage of prevalence through its respective epidemiological formula. Likewise, it is cross-sectional because it collected data in a single time: November 2022 – October 2023. Results: 46.7% experienced mild depression, 41.7% moderate depression and 11.6% severe depression. 55% of those interviewed were male and 45% female. The actual prevalence of depression is 100%. Likewise, the psychosocial risk factors identified were: the absence of recreational activities and social support networks, the economy, health services and family disintegration. Finally, it is necessary to design and implement socio-health intervention projects in the locality and with a socio-cultural perspective that impacts this age group, the family and from an intergenerational perspective, with the promotion of mental health being a priority goal in their execution.","PeriodicalId":496559,"journal":{"name":"Cross current international journal of medical and biosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140462158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe Bacterial Balanitis in Circumcised Adult Males","authors":"José Mazuecos-Blanca, José Rafael Mazuecos-Gutiérrez, Ana Jiménez-Gil","doi":"10.36344/ccijmb.2024.v06i01.003","DOIUrl":"https://doi.org/10.36344/ccijmb.2024.v06i01.003","url":null,"abstract":"Balanitis is the inflammation of the glans penis while balanoposthitis involves both the glans penis and prepuce and occurs only in uncircumcised males. Balanitis is more common in uncircumcised males due to the occlusive effect of the foreskin, which facilitates smegma retention and bacterial and fungal overgrowth. Therefore, balanitis is rare after circumcision and severe balanitis is even rarer. In patients with recurrent balanoposthitis, circumcision is indicated, and the presence of diabetes should be ruled out. Diabetes mellitus is a frequent predisposing factor for Candida balanoposthitis and has been associated with male genital lichen sclerosus, which in progressive stages leads to phimosis. Circumcision is also indicated in the treatment of lichen sclerosus associated with phimosis. Candida albicans stands as the primary culprit in cases of acute infectious balanoposthitis, with aerobic bacteria constituting the second most common etiological factor. Among these bacteria, streptococci particularly groups B and D and staphylococci, notably S. aureus, are prevalent. Mixed infections may also occur. The typical clinical manifestations involve erythema and oedema accompanied by itching and/or pain. In instances of painful, erosive streptococcal balanoposthitis, severe balanopreputial oedema with purulent exudate can be observed. Staphylococcus haemolyticus, a prominent member of the coagulase-negative staphylococci of the skin microbiota, causes infections in the male urogenital tract, such as urinary tract infections, chronic prostatitis and epididymo-orchitis. However, it had not been associated with balanitis. Enterococcus faecalis is part of the normal gastrointestinal microflora and is also a frequent cause of urinary tract infections and of chronic prostatitis. Enterococcus has been associated with mild balanoposthitis in adults and E. faecalis has been described to cause balanoposthitis in young children, but its association with severe balanitis .....","PeriodicalId":496559,"journal":{"name":"Cross current international journal of medical and biosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140497069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between Intra Ocular Pressure and Body Mass Index of Diabetics Attending a Diabetic Care Centre in Port-Harcourt","authors":"Ademola, M. I. N, Ilochi, O. N, Obia, O, Opurum, H. C","doi":"10.36344/ccijmb.2024.v06i01.002","DOIUrl":"https://doi.org/10.36344/ccijmb.2024.v06i01.002","url":null,"abstract":"Diabetes mellitus is characterized by sustained elevation of blood sugar, which is the main body energy source derived from the food we eat. In Nigeria, diabetic management revolves around blood glucose control and less attention is given to eye care. The aim of the present study was to establish the relationship between Intra Ocular Pressure and Body Mass Index of Diabetics attending a Diabetes Care Centre in Port Harcourt. The Intra Ocular Pressure of the subjects was determined. Body Mass Index, was also determined. Fasting blood glucose was measured. Uncontrolled blood sugar for males were 30(53.6%), females, 23(52.3%). The relationship between fasting blood glucose and gender was not statistically significant (P<0.00). Most subjects were in over weight category (46%), normal (26%), obese (28%) and underweight (1%). 87% of the subjects had normal intra ocular pressure, 9% elevated intra ocular pressure and 4% had pathological condition. No association existed between Intra Ocular Pressure and Body Mass Index. This occurred because; most of the subjects had their blood sugar level under control. More diabetic care centres should be established and equipped by the government to care, educate and manage diabetic patients, thereby preventing them from developing visual impairment and blindness.","PeriodicalId":496559,"journal":{"name":"Cross current international journal of medical and biosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140505736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Joint Mobilization and its Resultant Effects","authors":"Chinonso Vincent Nweke, Nweke Chidera Augustine, Madume Madume, Anelechi Kenneth, John Nwolim Paul, Chioma Akunnaya Ohanenye","doi":"10.36344/ccijmb.2023.v05i03.004","DOIUrl":"https://doi.org/10.36344/ccijmb.2023.v05i03.004","url":null,"abstract":"Joint mobilization also called joint manipulation technique commonly used in a clinical setting to improve the range of movement of a joint in order to prevent stiffness and pain. Any joint which presents with pain or stiffness can be treated with mobilization except in rare instances such as where there is malignancy, bone infection, spinal cord compression or unhealed fracture. There are different grades of mobilization used to treat various conditions. Where there is significant local pain and inflammation, gentle mobilization is used (Grade 1 or 2) to help with pain relief and reduce inflammation by promoting movement. In conditions where there is not much pain but rather the main problem is joint stiffness, then a more vigorous mobilizing technique (Grade 3 or 4) can be used to help restore full range of movement. The manipulation can be considered as an advanced way of joint mobilization, because it shares the same biomechanical principles. So, in OMT, the manipulation consists on a linear translatoric movement (traction or gliding) performed in the joint’s resting position, through a high velocity, low amplitude and low force thrust. These linear translatoric thrust techniques are technically more difficult to perform, but equally effective and much safer than the rotatory thrusts that have been traditionally performed. The manipulations are performed with the aim of obtaining joint surface separation and restoring the gliding component in joints that, even if they show an appropriate end-feel, they are hypomobile when examining them. It is a very effective technique if it is performed correctly and if it is indicated, but in the opposite cases it also carries serious injury risk. Because of the risk it can carry, and because of the expertise grade it requires for its execution, the manipulation training, mainly in the spine, for those physical therapists who have demonstrated their experience in the joint mobilization. However, basic low risk and equally ...","PeriodicalId":496559,"journal":{"name":"Cross current international journal of medical and biosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135788886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Socioeconomic Status on Haematological Indices in Port Harcourt","authors":"Abiye Tamuno-Opubo, Rosemary Oluchi Stanley, Zosa Ugbana Deinye, Siyeofori Belema Dede, Joy Tonye Wihioka, Jerry Dumley Nwiyor, Clementina Barida Aggrey","doi":"10.36344/ccijmb.2023.v05i03.003","DOIUrl":"https://doi.org/10.36344/ccijmb.2023.v05i03.003","url":null,"abstract":"Background: The World Health Organization is saddled with the responsibilities of regulating health care services across the globe and had over the years provided reference values to various medical parameters for clinicians and medical research. However, due to socio-economic variations amidst different populations in various parts of the world, the standard reference values had significantly differed among different races, tribes, gender and socio-economic backgrounds. Consequently, several regions of the world now had their respective local medical references. Back home in Nigeria and Port Harcourt in particular, over-reliance on this WHO references still prevail as a result of the absence of our local reference data. To this end, this study therefore investigates the Effect of Socioeconomic Status on Haematological Indices in Port Harcourt Nigeria. Materials and Methods: A total of 112 participants across 3 different socio-economic classes (Upper, Middle and Lower Classes) were recruited into the study using well-structured questionnaires based on purposive non-probability sampling techniques. Blood samples were also aspirated and analysed for haematological parameters (Hb, PCV, RBC, WBC, Platelets) against their socio-economic variables (gender, level education, income level and nutritional intakes). Results and Discussions: Result from the study showed that both male and female haematological parameters were significantly (ρ≤0.05) different from the WHO reference. Significant difference in low and high level education was also noted among the educational group whereas the middle class education was not. The income level among the 3 economic classes and their nutritional groups were also significant (ρ≤0.05) whereas those on balanced diets were not. Conclusion: The study therefore concluded that gender, income, education and nutrition of the people of Port Harcourt significantly (ρ≤0.05) affected their haematological parameters as compared with the global .....","PeriodicalId":496559,"journal":{"name":"Cross current international journal of medical and biosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135867301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"D-Dimer as a Predictive Biomarker of Severity and Mortality in COVID-19 Patients","authors":"Firas Hussein","doi":"10.36344/ccijmb.2023.v05i03.002","DOIUrl":"https://doi.org/10.36344/ccijmb.2023.v05i03.002","url":null,"abstract":"Background: Since December 2019, Coronavirus has been spreading widely becoming a fatal global pandemic. We need to understand the pathophysiological mechanisms of the disease in order to determine early and effective predictive biomarkers for severity and mortality, therefore finding better treatment approaches. Object: We aim to investigate the predictive value of d-dimer in COVID-19 in order to determine the severity, mortality and the risk of developing thrombotic events. Methods: We enrolled patients with confirmed COVID-19 who referred to the COVID department at Tishreen University Hospital (Latakia, Syria) from May 2020 to March 2021. We retrospectively documented demographic characteristics, clinical data, laboratory parameters and chest computed tomography staging. We followed up the patients' clinical progress during hospitalization, as well as their need for supportive oxygen (invasive and non-invasive mechanical ventilation) and the occurrence of thrombotic complications during hospitalization. Finally, we listed the cases of recovery and death. Results: We included 284 patients (68.3% males and 31.7% females). The mean age was 65 years, ranging from 27 to 92. D-dimer was only obtained for 193 patients, which included 28 mild to moderate, 115 severe and 50 critically ill patients. D-dimer was elevated (≥ 500 ng/mL) in 110 patients. On admission, D-dimer level was associated with an increased clinical severity. It was higher in critically ill compared to moderate cases ([3397.5±3296.7]ng/mL vs [1066.1± 1963.2] ng/ml, P = 0.0001) as well as for radiographic severity ([626.5±1047.1] ng/mL vs [2262.6± 2751.2] ng/ml, P= 0.007), respectively. All of those who did not survive had increased D-dimer level upon admission. When compared between patients who survived and who died during hospitalization, a significantly higher D-dimer level was detected in non-survivors versus survivors ([3099.9±2808.2] ng/mL vs [1308.9± 2249.3] ng/ml, P= 0.0001). ...........","PeriodicalId":496559,"journal":{"name":"Cross current international journal of medical and biosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136099093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence of Obesity in Kalabari Kingdom","authors":"Confidence Waribo Ihua, John Nwolim Paul, Gospel Chimenma Dimkpa, Idawarifa Frank Cookey-Gam, Stanley Samuel Mboi, Amaka Azubuike Ogba, Joyce Chisa Obia, Kingsley Moses Amadi, Gloria Stanley Acra Jone","doi":"10.36344/ccijmb.2023.v05i03.001","DOIUrl":"https://doi.org/10.36344/ccijmb.2023.v05i03.001","url":null,"abstract":"Background: Information on the incidence of Obesity in western countries has been documented, whereas there is paucity of information in the incidence of obesity in Africa and in Nigeria in particular. This study was done to examine the rate of obesity among men and women in Kalabari between the ages of 12 to 65 with different communities taken as case study. Materials and Methods: The Body Mass Index (BMI) which is a ratio of weight per height square of a total of three hundred and four (304) subjects was studied. One hundred and eighty-seven (187) subjects were females while one hundred and seventeen (117) subjects were males. Obesity was measured by body mass index (BMI) with relative weight and height. BMI less than 18.5 was considered as underweight. BMI between 18.5 and 24.9 was considered as normal weight. BMI greater than or equal to 30 was considered as obese. Results and Discussion: Obesity increased in all sex and age groups from 12 to 65 years. Of the 104 subjects studied, 149 were considered to be obese. Relating with age group, increase in obesity was generally seen to be more in females than in males. The rate of obesity is highest in women between the ages of 31-40 with a percentage of 18.79, while the rate of obesity is highest in men between the ages of 51-65 with a percentage of 12.75. Conclusion: Body mass index, occupational background, eating habit and cultural practice (fattening room practice) have significant impact on increase of obesity.","PeriodicalId":496559,"journal":{"name":"Cross current international journal of medical and biosciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136364001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}