Quarterly Journal of Nuclear Medicine and Molecular Imaging最新文献

筛选
英文 中文
Dosimetrically determined activities in advanced differentiated thyroid carcinoma: controversies. 剂量测定晚期分化甲状腺癌的活性:争议。
IF 1.5 4区 医学
Quarterly Journal of Nuclear Medicine and Molecular Imaging Pub Date : 2019-09-01 DOI: 10.23736/S1824-4785.19.03211-4
M. Finessi, V. Liberini, D. Deandreis
{"title":"Dosimetrically determined activities in advanced differentiated thyroid carcinoma: controversies.","authors":"M. Finessi, V. Liberini, D. Deandreis","doi":"10.23736/S1824-4785.19.03211-4","DOIUrl":"https://doi.org/10.23736/S1824-4785.19.03211-4","url":null,"abstract":"The 2013/59 EURATOM directive defines all nuclear medicine applications for therapeutic purpose as a form of radiotherapy and underlines the need of both justification and optimization of these procedures, including radioactive iodine therapy (RAIT) with [131I] for metastatic differentiated thyroid cancer (DTC), In metastatic DTC, optimal activity to be administered to achieve the best response rate with limited toxicity is still a matter of debate and international guidelines do not provide univocal recommendations on the preferable use of empiric versus a dosimetry-based approach in these patients. The purpose of this literature review is to describe the possible limits of dosimetry in RAIT planning according to methodological aspects, tumoral heterogeneity and to report clinical data on the impact on patients' outcome of different approaches. Due to the lack of standardized dosimetry protocols and clinical data assessing the superiority of a dosimetry-based vs an empiric approach in these patients, there is a need of standardisation and prospective, properly conducted studies to validate and to assess the best approach.","PeriodicalId":48994,"journal":{"name":"Quarterly Journal of Nuclear Medicine and Molecular Imaging","volume":"259 1","pages":""},"PeriodicalIF":1.5,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68829943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信