Journal of vaccines, immunology and immunopathology最新文献

{"title":"Immunotherapy in the Treatment of a Brain Tumor","authors":"","doi":"10.29011/2575-789x.0001117","DOIUrl":"https://doi.org/10.29011/2575-789x.0001117","url":null,"abstract":"","PeriodicalId":488824,"journal":{"name":"Journal of vaccines, immunology and immunopathology","volume":"53 26","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141010070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID-19 Vaccination in South Asia-Challenges Faced, and Lessons Learnt","authors":"","doi":"10.29011/2575-789x.00011126","DOIUrl":"https://doi.org/10.29011/2575-789x.00011126","url":null,"abstract":"","PeriodicalId":488824,"journal":{"name":"Journal of vaccines, immunology and immunopathology","volume":"83 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141015450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Review of Cell Therapy Approaches to Autism: A Review of Clinical Trial","authors":"","doi":"10.29011/2575-789x.0001103","DOIUrl":"https://doi.org/10.29011/2575-789x.0001103","url":null,"abstract":"Autism Spectrum Disorders (ASD) are characterized by persistent social communication and interaction difficulties, as well as repetitive behavioral patterns, often accompanied by abnormalities of the immune system and inflammatory reactions. Stem cell-based therapies, particularly those involving stem cells, are being investigated as potential treatments. This review examines cellular and molecular ASD abnormalities, stem cell types, animal models, ongoing clinical trials, and therapy limitations. ASD, a complex neurodevelopmental disorder with early onset social communication challenges and repetitive behaviors, lacks effective treatments. New research links ASD to neuroinflammation, microglia and glucose metabolism. Ten clinical trials of cell therapy show generally positive results. Although cell therapies show promise, extensive research is needed. This abstract discusses the potential of cell therapy for conditions lacking effective treatments, including cerebral palsy and ASD. It acknowledges complexity and incomplete understanding of pathophysiology. Disparate results in ASD cell therapy trials raise concerns about therapeutic targets and approaches, which require refined preclinical studies. Global ASD prevalence has increased, but treatments for core symptoms remain inadequate. Stem cell therapies show potential. Non-pharmacological interventions, such as diet and supplements, can address comorbidities. This brief abstract summarizes the aim, methodology, key results and conclusions of the full article. This review analyzes the role of miRNAs in ASD onset and progression. It is exploring miRNAs as regulators of neural development, diagnostic biomarkers and therapeutic targets. Findings from in vivo and in vitro models, including induced pluripotent stem cells (iPSCs), highlight the miRNA impact on ASD phenotypes. miRNAs are critical to understanding ASD pathogenesis. This review discusses neural stem cell-derived extracellular vesicles (NSC-EVs) as a treatment for CNS disorders. It highlights the mechanisms, therapeutic roles and advantages of cell-free therapy of NSC-EVs. The prevalence of Neuropsychiatric Disorders (NPD) is increasing globally, without full understanding of pathophysiology and effective treatments. Human induced pluripotent stem cells (hiPSCs) offer patient-specific neuropharmacological study potential. Guidelines and best practices for hiPSC-based NPD studies, with emphasis on donor selection, experimental design, and translational relevance, aim to improve drug discovery and clinical translation.","PeriodicalId":488824,"journal":{"name":"Journal of vaccines, immunology and immunopathology","volume":"101 10","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136019405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comprehensive Review of 16 Existing Reviews that Investigate the Influence of Stress on the Onset and Exacerbation of Autoimmune Diseases","authors":"","doi":"10.29011/2575-789x.0001102","DOIUrl":"https://doi.org/10.29011/2575-789x.0001102","url":null,"abstract":"of 16 Existing Reviews that Investigate the Influence of Stress on the","PeriodicalId":488824,"journal":{"name":"Journal of vaccines, immunology and immunopathology","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135585972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Association Between Anxiety and Autoimmune Diseases: A Systematic Review and MetaAnalysis of 16 Studies","authors":"","doi":"10.29011/2575-789x.0001100","DOIUrl":"https://doi.org/10.29011/2575-789x.0001100","url":null,"abstract":"This comprehensive systematic review and meta-analysis encompassed 16 studies, involving a total of over 1.4 million participants, to investigate the association between anxiety and autoimmune diseases. The findings revealed a significant association, with individuals experiencing anxiety being 1.28 times more likely to develop autoimmune diseases compared to those without anxiety. The association was found to be stronger in women and individuals with severe anxiety. The study suggests that this association may be due to shared genetic risk factors, the impact of stress on the immune system, and the involvement of inflammation, a common feature of autoimmune diseases. Despite the robust evidence, the study acknowledges limitations such as the use of observational studies and varying study qualities. Future research endeavors should aim to unravel the precise mechanisms underlying the link between anxiety and autoimmune diseases","PeriodicalId":488824,"journal":{"name":"Journal of vaccines, immunology and immunopathology","volume":"191 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135208995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commemorating 123 years of Allergy Immunotherapy","authors":"","doi":"10.29011/2575-789x.000199","DOIUrl":"https://doi.org/10.29011/2575-789x.000199","url":null,"abstract":"","PeriodicalId":488824,"journal":{"name":"Journal of vaccines, immunology and immunopathology","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135485022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}