Vanja Đuričić, Ana Mitka, Valentin Kordić, Sara Đuričić, Ivan Diklić, M. Jukić
{"title":"The Correlation between Iron Level and Schizophrenia","authors":"Vanja Đuričić, Ana Mitka, Valentin Kordić, Sara Đuričić, Ivan Diklić, M. Jukić","doi":"10.26332/seemedj.v7i2.286","DOIUrl":"https://doi.org/10.26332/seemedj.v7i2.286","url":null,"abstract":"Schizophrenia is a complex psychiatric condition that, if not adequately treated, can affect functional limitations. The exact etiopathogenesis of schizophrenia remains unknown. Research suggests an interaction between many factors, including genetic susceptibility, environment and psychological processes. Specific authors describe the association of a valuable mineral in the human body, iron, with pathophysiological mechanisms and related etiological factors in the development of the severe mental illness of schizophrenia.Iron has important roles in the human body and affects various physiological processes. Some studies have shown a connection between the dysregulation of iron levels and the development of different mental disorders, including schizophrenia. Abnormal levels of iron in a specific region of the brain have been observed in people with schizophrenia. Iron levels may contribute to the pathogenesis of schizophrenia in combination with other genetic, environmental and dietary factors. Iron can also contribute to the better cognitive functioning of a patient with schizophrenia, and due to frequent malnutrition and undernourishment in this group of patients, it is crucial to take into account the need for routine hematological examinations and the determination of essential nutritional deficiencies.Finally, our goals were to systematically review the literature published in the last two decades using PubMed, Web of Science, Scopus and Google Scholar. We described the clinical aspects and etiological factors of schizophrenia. We determined whether schizophrenia can be associated with iron concentration disorders to recognize and identify potential patients with iron deficiency and treat them promptly in daily clinical practice.","PeriodicalId":488664,"journal":{"name":"Southeastern European medical journal","volume":"103 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141820988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Fureš, D. Vidosavljević, C. Lež, Žana Stanić, Dora Fureš, Zlatko Hrgović, Mario Fučkar, Željka Fureš
{"title":"Enlightenment and Freemasonry in the Life and Work of the Physician Joannis Baptistae Lalangue","authors":"R. Fureš, D. Vidosavljević, C. Lež, Žana Stanić, Dora Fureš, Zlatko Hrgović, Mario Fučkar, Željka Fureš","doi":"10.26332/seemedj.v7i2.291","DOIUrl":"https://doi.org/10.26332/seemedj.v7i2.291","url":null,"abstract":"Data on the educational and Freemasonry activities of Doctor Joannis Baptistae Lalangue have been relatively modestly represented in the scientific literature until now. Based on recent research, we have come to the realizations that give us a new context for the life and work of Lalangue, especially from the aspect of his social activity. All of the above had very significant repercussions on his entire public health work and especially on his journalistic and publishing work. John the Baptist Lalangue was a successful physician. During his medical studies in Vienna, he was recognized by Baron van Swieten, the first name in medicine of the Habsburg Monarchy. Recent knowledge speaks of his very notable Enlightenment and Freemasonry work, which largely determined his life and work. Lalangue has created a truly impressive literary work, which is closely related to his active Enlightenment and public Masonry engagement. The mentioned progressive Enlightenment engagement is also responsible for the fact that thanks to Lalangue, we already had printed medical original professional literature in the Croatian language in the second half of the 18th century. This directly changed the conditions in society, primarily in the field of public health, for the better, not only in Croatia but also throughout the Habsburg Monarchy.","PeriodicalId":488664,"journal":{"name":"Southeastern European medical journal","volume":" 666","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141823789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Željka Dragila, Lea Gvozdanović, Romana Marušić, Lana Maričić
{"title":"Sex-Related Differences in Characteristics and Therapy of Heart Failure Patients","authors":"Željka Dragila, Lea Gvozdanović, Romana Marušić, Lana Maričić","doi":"10.26332/seemedj.v7i2.284","DOIUrl":"https://doi.org/10.26332/seemedj.v7i2.284","url":null,"abstract":"Aim: To determine the differences in comorbidities, therapy and echocardiographic measures among patients hospitalized for heart failure relative to gender.Methods: The study included patients hospitalized for heart failure at the Department of Cardiovascular Diseases of the Clinical Hospital Center Osijek in the period from 1 January 2020 to 30 March 2021.Results: There were 200 patients included in the study, of which 100 (50%) were male and 100 (50%) were female. Female patients were older, while male patients more frequently had a history of coronary artery disease. Men had a higher dose of loop diuretic on admission to the hospital. No significant difference was found in the representation of beta blockers and ACE inhibitors in therapy with regard to gender. On the other hand, men more frequently used MRA, sacubitril/valsartan and antiplatelet medication at hospital admission. Male patients had a larger left ventricular end-diastolic diameter, left ventricular end-systolic diameter and a lower left ventricular ejection fraction (EF). Regarding the type of heart failure according to EF, 72% of men had HFrEF, 20% HFmrEF and 8% HFpEF. In women, 47% had HFrEF, 33% HFmrEF and 20% HFpEF. During hospitalization due to heart failure, 22 patients died, an equal number of men and women.Conclusion: This research confirmed the differences in risk factors and pathophysiology of heart failure between males and females. Medicine is progressing towards an individual approach to each patient, so further research will be needed to find the best therapy for both male and female patients.","PeriodicalId":488664,"journal":{"name":"Southeastern European medical journal","volume":"101 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141820710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Martina Kos, I. Drenjančević, S. Puseljic, Ivana Jukić
{"title":"Primary Hypertension in Children and Adolescents","authors":"Martina Kos, I. Drenjančević, S. Puseljic, Ivana Jukić","doi":"10.26332/seemedj.v7i2.287","DOIUrl":"https://doi.org/10.26332/seemedj.v7i2.287","url":null,"abstract":"The incidence of primary hypertension is on the rise in the pediatric population, with an approximate prevalence ranging from 3% to 5%. The most significant risk factors for the onset and development of primary hypertension are well-known, and some of them are preventable, including increased salt consumption and obesity. Connected with metabolic risk factors, elevated blood pressure in childhood is carried into adulthood. Primary hypertension is associated with attenuated vascular responses to various physiological stimuli in both peripheral microcirculation and systemic macrocirculation in adults and children. Endothelial dysfunction is one of the most important features of arterial hypertension, together with an increased level of oxidative stress – both determinants significantly contribute to all the pathophysiological changes observed in hypertension. Systemic arterial hypertension has emerged as a prevalent cardiovascular risk factor associated with substantial morbidity and mortality. Hence, the timely identification of individuals with elevated blood pressure and early-life blood pressure management could serve as a crucial strategy to mitigate the risk of cardiovascular disease and mortality in adulthood.","PeriodicalId":488664,"journal":{"name":"Southeastern European medical journal","volume":"104 41","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141821679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alma Lozančić, Maja Miškulin, I. Miškulin, Mirjana Grebenar Čerkez, Mato Matić, Vedrana Lanc Čurdinjaković, J. Kovačević
{"title":"Factors Associated with the Quality of Life of the Nurses","authors":"Alma Lozančić, Maja Miškulin, I. Miškulin, Mirjana Grebenar Čerkez, Mato Matić, Vedrana Lanc Čurdinjaković, J. Kovačević","doi":"10.26332/seemedj.v7i2.289","DOIUrl":"https://doi.org/10.26332/seemedj.v7i2.289","url":null,"abstract":"Aim of the study: Research aim was to investigate the quality of life of the nurses and to determine sociodemographic factors associated with lower quality of life.Methods: A convenience sample of 100 nurses from different medical institutions in Croatia was used. An anonymous on-line questionnaire containing sociodemographic questions was administered. Quality of life was measured using Short Form-36 (SF-36).Results: Lower general health was associated with the older age of nurses and those working only morning shifts. Lower vitality and mental health were associated with working only morning shifts. Other investigated factors showed no association with the quality of life of the nurses.Conclusion: The quality of life of the nurses is lower than the quality of life of the general population in Croatia, in domains related to the role limitations due to physical health, bodily pain, vitality and social functioning. Factors influencing the quality of life of the nurses are inconsistent with literature data and require further research.","PeriodicalId":488664,"journal":{"name":"Southeastern European medical journal","volume":" December","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141824272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neurodevelopmental Outcomes of Very Low Birth Weight Preterm Infants in the Regional Pediatric Clinic","authors":"Ivana Jurić, S. Puseljic","doi":"10.26332/seemedj.v7i2.285","DOIUrl":"https://doi.org/10.26332/seemedj.v7i2.285","url":null,"abstract":"Aim: To examine the incidence and etiology of neurodevelopmental outcomes in very low birth weight preterm infants, maternal and perinatal risk factors, comorbidities, and clinical presentation and compare with newborns of the same gestational age who did not develop a neurodevelopmental disorder.Methods: The research was conducted at the Pediatric Clinic in KBC (Clinical Hospital Center) Osijek. All newborns born from 1 January 2018 to 31 December 2019 with birth weight < 1,500 g and gestational age < 37 weeks are included in the research. The data were collected by reviewing medical records and the hospital’s IT system.Results: In the observed period, 120 children with birth weight < 1,500 g and gestational age < 37 weeks were born. Maternal and perinatal risk factors for premature birth include autoimmune diseases of the mother, infections during pregnancy and birth complications. Early complications that accompany the selected group are RDS, ROP, NEC, IVH, sepsis, congenital heart defects and glucose metabolism disorder. Slowed motor, cognitive and speech development are mostly influenced by low body weight, higher degree of IVH, lower AS in the first minute and the presence of NEC. Significant risk factors for death are gestational age < 25 weeks, body weight < 800 g, infections in pregnancy and autoimmune diseases of the mother.Conclusion: The neurodevelopmental outcome of very low birth weight preterm infants depends on a combination of comorbidities, as well as maternal, perinatal and neonatal risk factors.","PeriodicalId":488664,"journal":{"name":"Southeastern European medical journal","volume":"113 51","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141821191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Štefanija Kolačko, A. Kokot, Nina Čuljak, Jurica Predović, Martina Hrvačić, Franka Luetić, Marko Bašković
{"title":"Knowledge of Students in Health and Non-Health Studies about Diabetes Mellitus Type 1","authors":"Štefanija Kolačko, A. Kokot, Nina Čuljak, Jurica Predović, Martina Hrvačić, Franka Luetić, Marko Bašković","doi":"10.26332/seemedj.v7i2.290","DOIUrl":"https://doi.org/10.26332/seemedj.v7i2.290","url":null,"abstract":"Aim: The aim of this research paper is to examine and compare the knowledge of students in health and non-health studies about diabetes mellitus type 1. Namely, the research examined whether the respondents are sufficiently educated about the disease itself, treatment and preventive measures of diabetes type 1. Their knowledge was examined with regards to their age, gender and the type of studies they attend.Respondents and methods: The research was conducted as a cross-sectional study. 101 respondents participated in the research. An anonymous online questionnaire was used as a measuring instrument, which was created for the purpose of this research. The research was conducted in July and August 2022.Results: Most respondents have good knowledge about diabetes mellitus, which is evident in the correct answers to the questions in the survey questionnaire. Statistically, significant differences were found in the students’ knowledge with regards to their age, gender and type of study. Respondents who participate in health studies have a higher level of knowledge than respondents who do not participate in health studies. Female respondents have a higher level of knowledge than male respondents. Older respondents also have greater knowledge about the disease itself.Conclusion: Students who study health studies show a higher level of knowledge than students of other studies. Most of the respondents were well educated about type 1 diabetes mellitus. Diabetes is one of the biggest public health problems nowadays, and measures of prevention and education of the population should be implemented as much as possible in kindergartens, primary and secondary schools, colleges, hospitals, and the health system.","PeriodicalId":488664,"journal":{"name":"Southeastern European medical journal","volume":"104 35","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141820836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matea Prenc, Frano Perić, Irena Petričić, Mirjana Flegarić Bradić, Robert Rončević
{"title":"The Effectiveness of Bupropion in Cigarette Smoking Cessation - A Narrative Review","authors":"Matea Prenc, Frano Perić, Irena Petričić, Mirjana Flegarić Bradić, Robert Rončević","doi":"10.26332/seemedj.v7i2.300","DOIUrl":"https://doi.org/10.26332/seemedj.v7i2.300","url":null,"abstract":"Smoking is still a large indirect cause of premature death worldwide. The first line of treatment for smoking cessation is nicotine replacement therapy (NRT). Bupropion, a drug primarily developed as an antidepressant, in some countries is the first drug licensed for smoking cessation that is not associated with nicotine. The drug acts mostly through its inhibition of dopamine reuptake in the neuronal synapses, but other effects of bupropion may also have a role in smoking cessation. There have been many clinical studies of bupropion that have shown impressive results in helping patients with smoking cessation. Because of its antidepressant role, it is useful in smoking cessation in patients with depression. Through the years bupropion has proven to be a potential cost-effective alternative to NRT.","PeriodicalId":488664,"journal":{"name":"Southeastern European medical journal","volume":" 1287","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141823074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}