KlorofilPub Date : 2023-04-17DOI: 10.30821/kfl:jibt.v7i1.13519
Andi Dian Astriani
{"title":"UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL 70% KLIKA TURI (Sesbania grandiflora L.) TERHADAP Staphyloccous epidermidis DAN Propionibacterium acnes","authors":"Andi Dian Astriani","doi":"10.30821/kfl:jibt.v7i1.13519","DOIUrl":"https://doi.org/10.30821/kfl:jibt.v7i1.13519","url":null,"abstract":"<p class=\"abstrak\"><em>Acne</em><em> is</em> a skin disease that occurs due to bacterial infection, usually on the skin surface of the face, neck, chest, and back. The Turi plant is one plant with medicinal properties that can be used as an antibacterial. This study aims to determine the antibacterial activity of 70% ethanol extract of klika turi against Staphylococcus epidermidis and Propionibacterium acnes. Klika turi was extracted by reflux method using 70% ethanol solvent. They were testing the antibacterial activity of 70% ethanol extract against Staphylococcus epidermidis and Propionibacterium acnes using liquid dilution and agar diffusion methods. The results showed that the MIC values were 2.5% against Staphylococcus epidermidis and 5% against Propionibacterium acnes. Activity test with the diffusion method to obtain the diameter of the inhibition zone against Staphylococcus epidermidis at an extract concentration of 2.5%; 5%; 10%; and 20%, which is 7.35 mm; 8.67mm; 11.08 mm and 11.55 mm, while for Propionibacterium acnes at an extract concentration of 5%; 10%; and 20% obtained the diameter of the inhibition zone which is 8.77; 11.32mm; and 12.00mm. The results can be concluded that the 70% ethanol extract of klika Turi has effective antibacterial activity at a concentration of 10% against Staphylococcus epidermidis and Propionibacterium acnes.).</p>","PeriodicalId":484671,"journal":{"name":"Klorofil","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136242971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
KlorofilPub Date : 2023-04-14DOI: 10.30821/kfl:jibt.v7i1.14657
Hana Verdiani, Dinda Syafira, Husna Nugrahapraja
{"title":"MINI REVIEW: PENGEMBANGAN BIOSENSOR KOLORIMETRI BERBASIS AGREGASI NANOPARTIKEL EMAS","authors":"Hana Verdiani, Dinda Syafira, Husna Nugrahapraja","doi":"10.30821/kfl:jibt.v7i1.14657","DOIUrl":"https://doi.org/10.30821/kfl:jibt.v7i1.14657","url":null,"abstract":"<p class=\"abstrak\">Gold nanoparticle (AuNP) is a material commonly used in colorimetric detection for biological sensors due to its low production cost, simplicity, and ease use. AuNP is known to generate different colors depending on the particle aggregation level. In the last two decades, changes in AuNP aggregation status have become the basis for developing a sensor to detect analytes in the sample. The solution color changes could be observed without sophisticated equipment, allowing ,more straightforward interpretation of the detection result. This review focuses on developing AuNP aggregation-based colorimetric tests for detecting various biological analytes. It discusses multiple mechanisms, strategies, functionalization, the latest research, and perspectives of AuNP use in colorimetric detection, which could be considered for future biosensor development. The concept of colloidal gold nanoparticle aggregation and stabilization is emphasized in this review. </p>","PeriodicalId":484671,"journal":{"name":"Klorofil","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135085983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}