طب پیشگیری طبری最新文献

The Role of Vitamin E and Sodium Selenite Supplementation on the Apoptosis of Renal Cells from Mice under the Electromagnetic Field Exposure 补充维生素E和亚硒酸钠对电磁场照射下小鼠肾细胞凋亡的影响

طب پیشگیری طبری Pub Date : 2023-09-01 DOI: 10.32598/tbsrj.v5i2.10531

Mohammad Eyvazi, Azam Taheri, Abbas Majidi, Reza Iraei

{"title":"The Role of Vitamin E and Sodium Selenite Supplementation on the Apoptosis of Renal Cells from Mice under the Electromagnetic Field Exposure","authors":"Mohammad Eyvazi, Azam Taheri, Abbas Majidi, Reza Iraei","doi":"10.32598/tbsrj.v5i2.10531","DOIUrl":"https://doi.org/10.32598/tbsrj.v5i2.10531","url":null,"abstract":"Introduction: By increasing the oxidative stress and the level of reactive oxygen species (ROS), electromagnetic field (EMF) is potentially able to damage body tissues, especially renal cells. Therefore, antioxidants by neutralizing the ROS may decrease the harmful effects caused by EMF. The aim of this study was to evaluate the effects of vitamin E and sodium selenite on the apoptosis of renal cells in mice under EMF exposure. Material and Methods: Forty-eight mice, weighing between 24-28 g, were under EMF exposure for 4 hours a day during 2 months. Mice were categorized into 6 groups, containing 6 mice in each group, and were treated with vitamin E or sodium selenite or both. The control group received nothing. To evaluated the apoptosis rate, mice were sacrificed through cervical dislocation and the right kidney was extracted in the end of intervention period. Apoptosis rate was assessed by Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) staining. Results: It was detected that apoptosis was significantly increased in the EMF exposed mice. Treatment with vitamin E resulted in significantly decreased apoptotic cells in the EMF exposed mice. However, sodium selenite was unable to significantly decrees the apoptosis in the EMF exposed mice. Combinational therapy of vitamin E and sodium selenite resulted in more decreased apoptotic cells in comparison to the mice receiving only the vitamin E. Conclusion: Combinational therapy of vitamin E and sodium selenite has beneficial effects in reducing the harmful effects of EMF on renal cells.","PeriodicalId":482135,"journal":{"name":"طب پیشگیری طبری","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135248246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of COVID-19 Anxiety in Nurses and Midwife Personnel in the Teaching Hospitals Affiliated to Mazandaran University of Medical Sciences 马赞达兰医科大学附属教学医院护士与助产士新冠肺炎焦虑状况比较

طب پیشگیری طبری Pub Date : 2023-09-01 DOI: 10.32598/tbsrj.v5i2.10534

Samira Khanmohammadi, Mohadeseh Basirat, Majid Dastras, Mohammad Taha Saadati Rad, Farinaz Saeidi, Saeedeh Azizi Mahkooyeh

{"title":"Comparison of COVID-19 Anxiety in Nurses and Midwife Personnel in the Teaching Hospitals Affiliated to Mazandaran University of Medical Sciences","authors":"Samira Khanmohammadi, Mohadeseh Basirat, Majid Dastras, Mohammad Taha Saadati Rad, Farinaz Saeidi, Saeedeh Azizi Mahkooyeh","doi":"10.32598/tbsrj.v5i2.10534","DOIUrl":"https://doi.org/10.32598/tbsrj.v5i2.10534","url":null,"abstract":"Introduction: The spread of the coronavirus, its high transmission rate, and lack of a definitive treatment for the novel disease have led to psychological disturbances in societies. Nurses are exposed to numerous psychological issues as they are on the frontline in the battle against COVID-19. The present study aimed to compare nurses and midwife personnel in terms of the anxiety caused by COVID-19. Material and Methods: This descriptive, cross-sectional study was conducted on 130 nursing staff and midwife personnel working in the teaching hospitals affiliated to Mazandaran University of Medical Sciences, Iran. The participants were selected via convenience sampling. Data were collected using a corona disease anxiety scale, which was completed in a self-report manner. Data analysis was performed in SPSS version 16 using descriptive statistics (tables, mean, and standard deviation) and inferential statistics. Results: The mean anxiety level of the nurses and midwife personnel was estimated at 30.33 ± 7.6 and 31.11 ± 9.03, respectively. However, the Mann-Whitney U test was indicative of no significant difference in this regard (P=0.08). Conclusion: According to the results, the nursing and midwife personnel had similar levels of COVID-19 anxiety. Given the moderate anxiety level of the healthcare staff regardless of their work environment, it is recommended that special programs be considered by hospital managers to psychologically support the staff.","PeriodicalId":482135,"journal":{"name":"طب پیشگیری طبری","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135248236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of Stress-Inducing Factors and Preoperative Anxiety and Their Mitigation Strategies from Patients' Perspectives in Surgical Departments of Educational Medical Centers at Mazandaran University of Medical Sciences in 2023 2023年马赞达兰医科大学教育医学中心外科患者应激诱发因素与术前焦虑的调查及缓解策略

طب پیشگیری طبری Pub Date : 2023-09-01 DOI: 10.32598/tbsrj.v5i2.10533

Hodeise Asadpour Sorkhkolaee, Mahsa Mokarrami Rostami, Ali Pahnabi

{"title":"Investigation of Stress-Inducing Factors and Preoperative Anxiety and Their Mitigation Strategies from Patients' Perspectives in Surgical Departments of Educational Medical Centers at Mazandaran University of Medical Sciences in 2023","authors":"Hodeise Asadpour Sorkhkolaee, Mahsa Mokarrami Rostami, Ali Pahnabi","doi":"10.32598/tbsrj.v5i2.10533","DOIUrl":"https://doi.org/10.32598/tbsrj.v5i2.10533","url":null,"abstract":"Introduction: In light of the progress made in anesthesia and surgical procedures resulting in fewer complications and greater success rates, preoperative stress and anxiety persist among patients. This study aimed to evaluate stress-inducing factors and preoperative anxiety and explore strategies for their mitigation among surgical patients. Material and Methods: This descriptive-analytical study was conducted in 2023 on 375 surgical patients in the operating room departments of educational medical centers affiliated with Mazandaran University of Medical Sciences. Simple random sampling was employed and a questionnaire designed by the researchers was used to collect data (with Cronbach's alpha reliability coefficient of 0.81). The data were analyzed via SPSS 20 software. Results: The study revealed that 60% of the total participants were male, with a mean age of 40 years. Moreover, 72% of the participants were married. The preoperative stress factors had a mean score of 7.29, with the next most significant factors being stress-inducing factors related to the department (19.6%), followed by stress-inducing factors related to the surgical staff (13.2%), and stress-inducing factors from the physical environment of the operating room (11.4%). Conclusion: The final results of this study suggest that by identifying influential factors on preoperative stress and addressing them, it is possible to minimize preoperative anxiety. Therefore, it is recommended to develop educational programs for physicians and personnel to alleviate stress-inducing factors and provide patients with essential information about surgical complications, the surgical process, and anesthesia procedures.","PeriodicalId":482135,"journal":{"name":"طب پیشگیری طبری","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135249504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

HER2 Amplification in Non-Mutant RAS Status in Patients with Metastatic Colorectal Cancer and the 2-Year Survival Rate 转移性结直肠癌患者非突变RAS状态的HER2扩增与2年生存率

طب پیشگیری طبری Pub Date : 2023-09-01 DOI: 10.32598/tbsrj.v5i2.10530

Ehsan Zaboli, Davood Shirazi MajiMiriha, Farshad Naghshvar, Reza Alizadeh-Navaei, Masumeh Shirazi HajiMiriha

{"title":"HER2 Amplification in Non-Mutant RAS Status in Patients with Metastatic Colorectal Cancer and the 2-Year Survival Rate","authors":"Ehsan Zaboli, Davood Shirazi MajiMiriha, Farshad Naghshvar, Reza Alizadeh-Navaei, Masumeh Shirazi HajiMiriha","doi":"10.32598/tbsrj.v5i2.10530","DOIUrl":"https://doi.org/10.32598/tbsrj.v5i2.10530","url":null,"abstract":"Introduction: HER2 amplification is a therapeutic target in breast and stomach cancer, but the relationship between HER2 and response to treatment in metastatic colorectal cancer has not been fully determined. This study investigated the incidence of HER2 overexpression in non-mutant RAS patients with metastatic colorectal cancer to determine the two-year survival rate in patients referred to Imam Khomeini Hospital in Sari between 2014-2018. Material and Methods: This cohort study was conducted between 2014 and 2018 among patients with metastatic colorectal cancer who were identified as non-mutant (wild) NRAS, KRAS, and BRAF genes. Patients received cetuximab. The clinical course of the patients was evaluated simultaneously during this evaluation period, and the two-year survival rate of the patients and the response to cetuximab were evaluated. Data were entered into SPSS software version 24 and analyzed. Results: Twenty-five patients were examined, 60% were men. The most common symptom in patients was abdominal pain (32%). The majority (72%) of the study patients did not undergo surgery, 24% underwent hemicolectomy and 4% underwent total colectomy. The incidence of HER2 positive in women was higher than in men (10% vs. 6%) and in grade 1 patients was higher than grade 2 (8.3% vs. 1.1%). Forty-four percents of patients had positive two-year survival. Among patients with positive two-year survival, 9.1% were HER2 positive and 90.9% were HER2 negative. Conclusion: The results of the study showed that infectious causes (influenza) and underlying CLD including asthma were major causes of ARF in pregnant women. Thus, more careful attention is needed to control the underlying disease, and planning for easier access to the influenza vaccine can play an effective role in reducing the incidence of pulmonary infections.","PeriodicalId":482135,"journal":{"name":"طب پیشگیری طبری","volume":"370 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135249466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrolyte Disturbances in Post-Acute Myocardial Infarction Arrhythmias 急性心肌梗死后心律失常的电解质紊乱

طب پیشگیری طبری Pub Date : 2023-09-01 DOI: 10.32598/tbsrj.v5i2.10535

Seyede Zakieh Seyedi, Maryam Zahedi, Parisa Farahani, Hamidreza Azimi

{"title":"Electrolyte Disturbances in Post-Acute Myocardial Infarction Arrhythmias","authors":"Seyede Zakieh Seyedi, Maryam Zahedi, Parisa Farahani, Hamidreza Azimi","doi":"10.32598/tbsrj.v5i2.10535","DOIUrl":"https://doi.org/10.32598/tbsrj.v5i2.10535","url":null,"abstract":"Introduction: Electrolyte disturbances are an important predictor for the prediction of arrhythmias after acute myocardial infarction (AMI). This study investigated the prevalence and relationship of various electrolyte disorders with common types of arrhythmias after AMI. Material and Methods: This cross-sectional study was performed on 153 patients with arrhythmias after AMI. Patient's demographic variables were collected from patient files and required laboratory findings including serum potassium (K), calcium (Ca), and magnesium (Mg) were measured in the first 12 hours after AMI. Any type of serum electrolyte disturbance was defined as a value above or below the reference values. The incidence of any arrhythmias during hospitalization was determined for each group of electrolyte disturbances using chi-square test and fisher exact test. Logistic regression was used in order to evaluate the risk of any arrhythmias in association with serum electrolyte levels. Results: In this study, the most common arrhythmias after AMI were inappropriate sinus tachycardia (IST) (43.1%), sinus bradycardia (33.3%), and premature ventricular contractions (30.7%), respectively. Majority of subjects had normal levels of serum K and Ca levels (P=0.001). Also, most of the patients with ventricular tachycardia and SB were in the range of normokalemia (P=0.015) and normocalcemia (P=0.035), respectively. The risk of IST increases by 1.911 times for every 0.648 units increase in K (P=0.033). However, no significant relationship was seen between other electrolyte disturbances and any other post-AMI arrhythmias. Conclusion: Occurrence of IST increases with higher levels of K. lack of association between other serum electrolytes levels and arrhythmias indicate the importance of further studies in this regard with consideration of other affecting factors.","PeriodicalId":482135,"journal":{"name":"طب پیشگیری طبری","volume":"193 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135249509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigating the Antimicrobial Activity of Different Extracts of Echium on Selected Gram-Positive and Gram-Negative Bacteria 不同提取物对革兰氏阳性菌和革兰氏阴性菌抑菌活性的研究

طب پیشگیری طبری Pub Date : 2023-09-01 DOI: 10.32598/tbsrj.v5i2.10532

Masoud Kavehei, Seyed Hasan Sefidroo

{"title":"Investigating the Antimicrobial Activity of Different Extracts of Echium on Selected Gram-Positive and Gram-Negative Bacteria","authors":"Masoud Kavehei, Seyed Hasan Sefidroo","doi":"10.32598/tbsrj.v5i2.10532","DOIUrl":"https://doi.org/10.32598/tbsrj.v5i2.10532","url":null,"abstract":"Introduction: Medicinal plants have had a special value and importance in providing health and wellness of communities both in terms of treatment and prevention of diseases. The aim of this research was to investigate the antimicrobial activity of different extracts (aqueous, ethanolic, and methanolic) of two types of Echium (Helioteropium ellipticum and Anchusa strigosa) on Staphylococcus aureus, Bacillus Cereus, Escherichia Coli, Salmonella Typhi and Shigella dysentery bacteria. Material and Methods: Extracts were prepared by soaking method. Antimicrobial activity was determined by two methods: dilution sequence in liquid medium and diffusion from disk in solid medium. The data were analyzed with SPSS24 software. Results: Gram-positive bacteria showed more sensitivity to the extracts than Gram-negative bacteria. Antimicrobial activity of Heliotropium ellipticum was more than Anchusa strigosa. Aqueous extract has the lowest and ethanolic extract has the highest antimicrobial activity. Staphylococcus aureus showed the highest and Escherichia coli the lowest sensitivity to the extracts. Staphylococcus aureus bacteria showed the largest diameter of non-growth aura (20.67 mm) at the concentration of 50 mg/ml of ethanolic extract, and the MIC of Staphylococcus aureus had the highest sensitivity at 312.5 PPM dilution. Conclusion: The two tested species have good antimicrobial activity and they can be used as natural substitutes for chemical antimicrobial agents.","PeriodicalId":482135,"journal":{"name":"طب پیشگیری طبری","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135248197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Post-Traumatic Stress Disorder on Sleep Quality in Family Members of Trauma Patients Admitted to The Intensive Care Unit 创伤后应激障碍对重症监护室创伤患者家属睡眠质量的影响

طب پیشگیری طبری Pub Date : 2023-09-01 DOI: 10.32598/tbsrj.v5i2.10536

Abbas Faramarzi, Seyed Afshin Shorofi, Khadijeh Yazdi, Mahin Tatari, Ravanbakhsh Esmaeili

{"title":"Effects of Post-Traumatic Stress Disorder on Sleep Quality in Family Members of Trauma Patients Admitted to The Intensive Care Unit","authors":"Abbas Faramarzi, Seyed Afshin Shorofi, Khadijeh Yazdi, Mahin Tatari, Ravanbakhsh Esmaeili","doi":"10.32598/tbsrj.v5i2.10536","DOIUrl":"https://doi.org/10.32598/tbsrj.v5i2.10536","url":null,"abstract":"Introduction: The hospitalization of individuals who have experienced trauma has a significant impact on their family members' lives. Consequently, the objective of this study was to examine the influence of post-traumatic stress disorder (PTSD) on the sleep quality of family members whose loved ones were hospitalized in the intensive care unit (ICU). Material and Methods: This descriptive-analytical cross-sectional study involved 120 participants (66 males and 54 females) who were first-degree relatives of trauma patients admitted to the ICU at 5th Azar Hospital in Gorgan. Within the first 24 hours of the trauma patient's admission to the ICU, one of their first-degree relatives completed the PCL-C questionnaire for assessing PTSD symptoms. If the participant obtained a score of 45 or higher on the PCL-C questionnaire, they were then requested to complete the Pittsburgh sleep quality questionnaire. Statistical analyses were conducted using SPSS 23 software. Results: The study found that the average score for PTSD among participants was 67.8 ± 5, indicating a high level of stress. The sleep quality score for family members of trauma patients upon hospitalization was 3.9 ± 1.8 (acceptable). However, one month later, their sleep quality significantly deteriorated to a score of 9.3 ± 2.5 (poor) (P < 0.001). There was no significant association found between sleep quality and PTSD (P > 0.05). Conclusion: The research findings indicate that the admission of a trauma patient to the ICU has a significant negative impact on the sleep quality of their family members. Although PTSD was prevalent among these individuals, it did not directly influence sleep quality. Nevertheless, addressing psychological issues and providing adequate psychological support are crucial for improving sleep quality and managing PTSD-related problems, especially for patients with severe complications.","PeriodicalId":482135,"journal":{"name":"طب پیشگیری طبری","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135248248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0