{"title":"A Rare Case of Pulmonary Veno-Occlusive Disease, Pulmonary Capillary Hemangiomatosis","authors":"Kirubel Zemedkun Gebreselassie","doi":"10.47363/jprr/2023(5)148","DOIUrl":"https://doi.org/10.47363/jprr/2023(5)148","url":null,"abstract":"A 40-year-old male with past medical history of chronic pain on methadone for a few years, hypertension, and obesity presented with worsening dyspnea and was found to have significant hypoxemia. A CT-angiogram of the chest showed extensive diffuse bilateral pulmonary infiltrates with bilateral hilar and mediastinal lymphadenopathy.","PeriodicalId":477116,"journal":{"name":"Journal of pulmonology research & reports","volume":"2022 45","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135768838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case Study: A Case Report of Human Monkeypox with Unusual Features","authors":"Dr Bharti Sharma","doi":"10.47363/jprr/2023(5)147","DOIUrl":"https://doi.org/10.47363/jprr/2023(5)147","url":null,"abstract":"The case report of an unusual case of human monkeypox with atypical epidemiology, unknown transmission route and unusual as well as rare ocular involvement with severe symptoms is presented in this case study","PeriodicalId":477116,"journal":{"name":"Journal of pulmonology research & reports","volume":"9 16","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135765190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Percentage and Absolute CD4+ Count and Factors Influencing Their Levels in Tuberculosis Patients in a Tetiary Hospital, Kaduna, Nigeria","authors":"Madaki Suzie, Yusuf Mohammed","doi":"10.47363/jprr/2023(5)146","DOIUrl":"https://doi.org/10.47363/jprr/2023(5)146","url":null,"abstract":"Background: The role of CD4+ T cells in immunity against tuberculosis have been widely acknowledged. This study determined CD4+ absolute, CD4 percentage and haemoglobin (HB) levels in tuberculosis (TB) patients undergoing TB treatment and compared these levels with presence of some factors which could modify the quantities of CD4+, CD4% and HB in TB patients. Methods: A cross-sectional study of eighty-five persons attending TB DOTS clinic in tertiary hospital between 2020 to 2021. Multicolour fluorescence imaging and absorbance spectrometry microscopy was used to enumerate CD4+ absolute count, CD4+ percentage and HB concentration in whole blood. Questionnaire and interviews were used to determine history, demographic data, BCG vaccination, BCG scar, vitamin A supplementation, awareness of zoonotic diseases and zoonotic TB, maternal BCG vaccination status, maternal BCG scar and undernutrition for each respondent. Results: CD4% significantly differed between forty-seven males (mean age: 33.5) and thirty-eight females (mean age: 32.2) (p <0.05). T-test indicated no significant difference in CD4+ count, CD4% and HB compared with BCG vaccination status, presence of BCG scar, knowledge of zoonotic diseases, knowledge of zoonotic TB and with vitamin A supplementation (p <0.05). There was also significant difference in CD4% compared with undernutrition and in absolute CD4+ counts compared with drug resistance (p <0.05). Conversely, there was significant difference in CD4% and absolute CD4+ count when compared with maternal BCG vaccination, presence of maternal BCG Scar. Pearson correlation coefficient indicated weak negative relationship between CD4%, absolute CD4+ count and age. Also, weak positive relationship between HB and age. Both relationships were not significant (p <0.05). Conclusion: Undernutrition, gender, maternal BCG vaccination (with or without scaring) and age influence levels of CD4+ in TB patients.","PeriodicalId":477116,"journal":{"name":"Journal of pulmonology research & reports","volume":"7 39","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135765866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Does Thromboelastography in Non-Trauma Critical Care Patients Promote The Judicious Use of Blood Products? A Retrospective Exploratory Single Center Observational Study","authors":"Stephen L Yu, Bathmapriya Balakrishnan","doi":"10.47363/jprr/2023(5)143","DOIUrl":"https://doi.org/10.47363/jprr/2023(5)143","url":null,"abstract":"Background: Thromboelastography (TEG) revolutionized the resuscitation of critically ill trauma and cirrhotic patients by improving blood product utilization and survival outcomes. There is limited data on the application and outcomes of non-trauma critical care (NTCC) patients with TEG use. This study compares the blood product utilization, mortality, and other outcomes of NTCC patients using TEG or CCT-guided transfusion. Methods: This is a single-center retrospective observational exploratory study of adult NTCC patients admitted to the medical intensive care unit in a rural academic center. Eligible patients received transfusion of blood products (BPs) guided by CCT or TEG studies. The primary outcome compared BPs transfused. Secondary outcomes included methods to achieve hemostasis, 28-day readmission rate after discharge, and 28-day survival. Results: TEG was used in 80 (70.8%) patients. The TEG group received 4.5 more units of BPs than the CCT group (p=0.003). A clinically significant difference in BPs transfused was seen in packed red blood cells (p=0.064), platelets (p=0.003), and fresh frozen plasma (p=0.020). The methods to achieve hemostasis between the groups were statistically significant (p=0.021). The 28-day readmission-free rate was similar (42.5% vs. 54.5%, TEG vs. CCT, p=0.301), as was the 28-day survival after discharge (p=0.078) in both groups. Conclusions: TEG-guided transfusion increased the number of BPs transfused compared to CCT in NTCC patients. No difference between the two groups in achieving hemostasis, 28-day readmission rate, or 28-day mortality was observed. This study highlights the need to further analyze TEGguided resuscitation prior to adopting TEG into routine practice in NTCC settings.","PeriodicalId":477116,"journal":{"name":"Journal of pulmonology research & reports","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136037360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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