Mehmet Rami Helvaci, Valeria Pappel, Kubra Piral, Selim Ozer, Mehpar Camlibel, Huseyin Sencan, Ramazan Davran, Abdulrazak Abyad, Lesley Pocock
{"title":"As a good prognostic sign, Autosplenectomy is higher in females in Sickle Cell Diseases","authors":"Mehmet Rami Helvaci, Valeria Pappel, Kubra Piral, Selim Ozer, Mehpar Camlibel, Huseyin Sencan, Ramazan Davran, Abdulrazak Abyad, Lesley Pocock","doi":"10.5742/mejn2023.9378042","DOIUrl":"https://doi.org/10.5742/mejn2023.9378042","url":null,"abstract":"Background: Sickle cell diseases (SCDs) are inborn and destructive processes on vascular endothelium, particularly at the capillaries. Methods: All patients with the SCDs were included. Results: We studied 222 males and 212 females with similar ages (30.8 vs 30.3 years, p>0.05, respectively). Although the higher prevalence of autosplenectomy (50.4% vs 53.3%, p<0.05), transfused units of red blood cells (RBCs) in their lives (48.1 vs 28.5, p=0.000), disseminated teeth losses (5.4% vs 1.4%, p<0.001), ileus (7.2% vs 1.4%, p<0.001), cirrhosis (8.1% vs 1.8%, p<0.001), leg ulcers (19.8% vs 7.0%, p<0.001), clubbing (14.8% vs 6.6%, p<0.001), coronary heart disease (CHD) (18.0% vs 13.2%, p<0.05), chronic renal disease (CRD) (9.9% vs 6.1%, p<0.05), chronic obstructive pulmonary disease (COPD) (25.2% vs 7.0%, p<0.001), and stroke (12.1% vs 7.5%, p<0.05) were all lower in females. Conclusion: The sickled or just hardened RBCs-induced capillary endothelial damage initiates at birth, and terminates with multiorgan failures even at childhood. Although RBCs suspensions and corticosteroids in acute, and aspirin with an anti-inflammatory dose plus low-dose warfarin plus hydroxyurea both in acute and chronic phases decrease severity, survivals are still shortened in both genders, dramatically. Although the higher prevalence of autosplenectomy, transfused units of RBCs in their lives disseminated teeth losses, ileus, cirrhosis, leg ulcers, clubbing, CHD, CRD, COPD, and stroke were all lower in females. So there may be an inverse relationship between autosplenectomy and severity of SCDs, and spleen may act as a chronic inflammatory focus as a filter of blood for these sickled or just hardened RBCs. Key words: Sickled or just hardened red blood cells, capillary endothelial edema, myocardial infarction, stroke, sudden deaths, autosplenectomy, female gender","PeriodicalId":476864,"journal":{"name":"Middle East Journal of Nursing","volume":"115 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136053940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mehmet Rami Helvaci, Valeria Pappel, Kubra Piral, Selim Ozer, Mehpare Camlibel, Huseyin Sencan, Ramazan Davran, Abdulrazak Abyad, Lesley Pocock
{"title":"Male Gender alone may be a bad Prognostic Factor in Sickle Cell Diseases","authors":"Mehmet Rami Helvaci, Valeria Pappel, Kubra Piral, Selim Ozer, Mehpare Camlibel, Huseyin Sencan, Ramazan Davran, Abdulrazak Abyad, Lesley Pocock","doi":"10.5742/mejn2023.9378043","DOIUrl":"https://doi.org/10.5742/mejn2023.9378043","url":null,"abstract":"Background: Sickle cell diseases are inborn and destructive processes on vascular endothelium, particularly at the capillaries. Methods: All patients were included. Results: We studied 222 males and 212 females with similar ages (30.8 vs 30.3 years, p>0.05, respectively). Smoking (23.8% vs 6.1%, p<0.001), alcohol (4.9% vs 0.4%, p<0.001), transfused red blood cells (RBCs) in their lives (48.1 vs 28.5 units, p=0.000), disseminated teeth losses (5.4% vs 1.4%, p<0.001), chronic obstructive pulmonary disease (COPD) (25.2% vs 7.0%, p<0.001), ileus (7.2% vs 1.4%, p<0.001), cirrhosis (8.1% vs 1.8%, p<0.001), leg ulcers (19.8% vs 7.0%, p<0.001), clubbing (14.8% vs 6.6%, p<0.001), coronary heart disease (CHD) (18.0% vs 13.2%, p<0.05), chronic renal disease (CRD) (9.9% vs 6.1%, p<0.05), and stroke (12.1% vs 7.5%, p<0.05) were all higher, and autosplenectomy (50.4% vs 53.3%, p<0.05) and mean age of mortality were lower in males (30.2 vs 33.3 years, p<0.05). Conclusion: The sickled or just hardened RBCs-induced capillary endothelial damage initiates at birth, and terminates with multiorgan failures even at childhood. Although RBCs suspensions and corticosteroids in acute, and aspirin with an anti-inflammatory dose plus low-dose warfarin plus hydroxyurea both in acute and chronic phases decrease severity, survivals are still shortened in both genders, dramatically. Transfused units of RBCs in their lives, disseminated teeth losses, COPD, ileus, cirrhosis, leg ulcers, clubbing, CHD, CRD, and stroke were all higher, and autosplenectomy and mean age of mortality were lower in males which can not be explained by effects of smoking and alcohol alone at these younger mean ages, relatively. Key words: Sickle cell diseases, sickled or just hardened red blood cells, capillary endothelial edema, myocardial infarction, stroke, sudden deaths, male gender","PeriodicalId":476864,"journal":{"name":"Middle East Journal of Nursing","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136053929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Nursing Profession in the new era of Saudi Arabia","authors":"Alaa Mujallad","doi":"10.5742/mejn2023.9378041","DOIUrl":"https://doi.org/10.5742/mejn2023.9378041","url":null,"abstract":"People unfamiliar with Saudi Arabia will never realize the change the country is experiencing today. Women have become empowered over a short period. Change is happening now and is happening quickly. Women who have never even considered being engaged in higher positions are taking managerial and leadership positions. Along with the change that is taking place, the healthcare sector is one priority for the newly crowned prince Mohammed bin Salman in his 2030 vision to the nation. The Minister of Health addresses that nursing is the top priority to achieve the vision of the Kingdom of Saudi Arabia, pointing out that 50% of the total workforce in the health sector are nurses. The researcher used secondary data from the Ministry of Health in Saudi Arabia to do a Descriptive Comparative Research Design to compare the number of nursing students to medical students in the major public universities in Saudi Arabia to see if there is a big difference between choosing nursing and medicine in the light of the high demand for the nursing profession. Key Words: Nursing, Saudi Arabia, Nursing Shortage, Vision 2030","PeriodicalId":476864,"journal":{"name":"Middle East Journal of Nursing","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136053943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cultural Competence in Nurses in Saudi Arabia: A Systematic Review","authors":"Ahmad Aboshaiqah","doi":"10.5742/mejn2023.9378040","DOIUrl":"https://doi.org/10.5742/mejn2023.9378040","url":null,"abstract":"Background. Nursing staff are typically multi-national, especially in Saudi Arabia, and Saudi nurses deal with multicultural patients, which creates a culturally diverse atmosphere. As a result, cultural competence is essential. Aim. To assess cultural competence among nurses in Saudi Arabia Methods. A systematic review was performed to assess cultural competence among nurses in Saudi Arabia. Findings. The study provides in-depth summaries of 11 papers included in this review. No studies published before 2014 investigated the cultural competence of Saudi Arabian nurses. However, the authors noted a sharp rise from 2020 in the number of studies dealing with this issue. Sample sizes ranged from 11 to 650 participants. Three studies were qualitative compared to eight quantitative studies. Seven studies focused on staff nurses, one on academic nurses, two on nursing students, and one on nurse leaders. Three concentrated on the academic setting, seven on clinical settings, and one on community settings. Most studies collected data from surveys, while a few used interviews and cross-sectional methodologies. Conclusion. Healthcare systems should be structured to encourage the empowerment of nurses from different nationalities and build effective communication policies to improve cultural competency among nurses. Future research should look at the relationship between individual training programs designed to increase cultural competence and their effect on the quality of patient care. Also, further research should incorporate a more diverse range of cultures. Keywords: Cultural competence, nurses, Saudi Arabia, patient outcome, knowledge, skills, attitude.","PeriodicalId":476864,"journal":{"name":"Middle East Journal of Nursing","volume":"83 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136053931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Red Blood Cell supports prolong the Survival in Sickle Cell Diseases","authors":"Mehmet Rami Helvaci","doi":"10.5742/mejn2023.9378044","DOIUrl":"https://doi.org/10.5742/mejn2023.9378044","url":null,"abstract":"Background: Hardened red blood cells (RBCs)-induced capillary endothelial damage initiates at birth in sickle cell diseases. Methods: Patients with red blood cells (RBCs) transfusions of less than 50 units in their lives were put into the first and 50 units or higher were put into the second groups. Results: There were 224 cases in the first and 92 cases in the second groups. Mean ages were similar in them (28.9 vs 30.0 years, respectively, p>0.05). Although the lower prevalence of autosplenectomy (56.2% vs 45.6%, p<0.05), male ratio (45.5% vs 64.1%, p<0.001), white blood cells (WBCs) (14.931 vs 15.346/µL, p<0.05) and platelets (PLTs) (435.670 vs 498.310/µL, p= 0.005) counts, painful crises per year (3.8 vs 8.4, p= 0.000), smoking (12.0% vs 17.3%, p<0.05), clubbing (7.1% vs 15.2%, p<0.01), chronic obstructive pulmonary disease (COPD) (6.6% vs 20.6%, p<0.001), leg ulcers (11.6% vs 21.7%, p<0.01), stroke (5.8% vs 11.9%, p<0.05), chronic renal disease (CRD) (4.9% vs 14.1%, p<0.001), coronary heart disease (CHD) (4.0% vs 8.6%, p<0.05), and mean age of mortality (29.5 vs 34.6 years, p<0.05) were all higher in the second group. Conclusion: Although the lower prevalence of autosplenectomy, male ratio, WBCs and PLTs counts, painful crises per year, smoking, clubbing, COPD, leg ulcers, stroke, CRD, CHD, and mean age of mortality were higher in the second group. So autosplenectomy may be a good, and male gender alone may be a bad prognostic feature that can not be explained by smoking alone at the younger age, and RBCs supports prolong the survival. Key words: Sickle cell diseases, hardened red blood cells, capillary endothelial damage, capillary endothelial edema, myocardial infarction, stroke, red blood cell supports","PeriodicalId":476864,"journal":{"name":"Middle East Journal of Nursing","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136053934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}