Sriwijaya Journal of Internal Medicine最新文献

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Analysis of Risk Factors and Predictors of Success in Controlling Drop Out Pulmonary Tuberculosis: An Observational Study in Batang Regency, Indonesia 辍学肺结核控制成功的风险因素和预测因素分析：印度尼西亚巴塘地区的观察研究

Sriwijaya Journal of Internal Medicine Pub Date : 2024-07-04 DOI: 10.59345/sjim.v2i2.142

Teguh Irawan, Wahyuningsih, Anik Indriono, Muhammad Fatih Izul Maula, Meila Azzahra

{"title":"Analysis of Risk Factors and Predictors of Success in Controlling Drop Out Pulmonary Tuberculosis: An Observational Study in Batang Regency, Indonesia","authors":"Teguh Irawan, Wahyuningsih, Anik Indriono, Muhammad Fatih Izul Maula, Meila Azzahra","doi":"10.59345/sjim.v2i2.142","DOIUrl":"https://doi.org/10.59345/sjim.v2i2.142","url":null,"abstract":"Introduction: Pulmonary tuberculosis (TB) remains a significant public health problem in Batang Regency, Indonesia. The high drop out (DO) rate of treatment is one of the main obstacles in controlling TB. This study aims to identify risk factors and predictors of DO for pulmonary TB treatment in Batang Regency. \u0000Methods: An analytical observational study with a cross-sectional design was conducted in 2023 involving 150 pulmonary TB patients who were recorded as having DO in the 2021-2022 period. Primary data was collected through interviews and secondary data from medical records. Bivariate analysis using the Chi-square test or Fisher's exact test, and multivariate analysis using logistic regression were performed to identify risk factors and predictors of DO. \u0000Results: Bivariate analysis showed that young age (<25 years) (OR = 3.21; 95% CI: 1.54-6.69), long distance of residence from health facilities (OR = 4.12; 95% CI: 1.98-8.57), and a history of adverse drug reactions (ESO) (OR = 5.63; 95% CI: 2.65-11.94) were significant risk factors for DO. Multivariate analysis confirmed that young age (aOR = 2.95; 95% CI: 1.35-6.43), long distance of residence (aOR = 3.88; 95% CI: 1.79-8.41), and history of ESO (aOR = 5.12; 95% CI: 2.38-11.01) were independent predictors of DO. \u0000Conclusion: Young age, long distance of residence from health facilities, and history of ESO are risk factors and independent predictors of DO for pulmonary TB treatment in Batang Regency. Interventions that target these factors, such as intensive education and counseling for young patients, increased access to health services, and optimal management of ESO, are needed to increase the success of TB control. \u0000 ","PeriodicalId":470880,"journal":{"name":"Sriwijaya Journal of Internal Medicine","volume":" 47","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141680143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antibacterial Potential of Dewandaru Leaves (Eugenia uniflora L.) Against Escherichia coli: In Vitro Study Dewandaru 叶（Eugenia uniflora L.）对大肠杆菌的抗菌潜力：体外研究

Sriwijaya Journal of Internal Medicine Pub Date : 2024-06-05 DOI: 10.59345/sjim.v2i1.138

Riyan Setiyanto, Annisa Diyan Meitasari, Sinta Cantika Natasya, Dewi Weni

{"title":"Antibacterial Potential of Dewandaru Leaves (Eugenia uniflora L.) Against Escherichia coli: In Vitro Study","authors":"Riyan Setiyanto, Annisa Diyan Meitasari, Sinta Cantika Natasya, Dewi Weni","doi":"10.59345/sjim.v2i1.138","DOIUrl":"https://doi.org/10.59345/sjim.v2i1.138","url":null,"abstract":" \u0000Introduction: Escherichia coli is a pathogenic Gram-negative bacteria that commonly causes digestive tract infections, including diarrhea. Continuous use of antibiotics has led to an increase in bacterial resistance. Dewandaru leaves (Eugenia uniflora L.) have been known to have antibacterial activity against several pathogenic bacteria. This study aims to evaluate the antibacterial activity of dewandaru leaf extract against E. coli in vitro. \u0000Methods: Dewandaru leaves were extracted using the maceration method with 96% ethanol. The antibacterial activity test was carried out using the Kirby-Bauer disk diffusion method with gentamicin as a positive control and sterile NaCl as a negative control. The diameter of the inhibition zone was measured and analyzed statistically. \u0000Results: Dewandaru leaf extract shows antibacterial activity against E. coli with a significant zone of inhibition. An extract concentration of 80% showed moderate antibacterial activity, while concentrations of 40% and 60% did not show antibacterial activity. \u0000Conclusion: Dewandaru leaves have the potential to be a natural antibacterial agent against E. coli. Further studies are needed to isolate and identify the active compounds and evaluate the effectiveness and safety of dewandaru leaf extract in vivo.","PeriodicalId":470880,"journal":{"name":"Sriwijaya Journal of Internal Medicine","volume":"29 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141382631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

KDIGO 2021 Blood Pressure Target Update and Chronic Kidney Disease Progression KDIGO 2021 年血压目标更新与慢性肾病进展

Sriwijaya Journal of Internal Medicine Pub Date : 2023-12-18 DOI: 10.59345/sjim.v1i2.78

Guo Jifei, Yinliang Xi, Article Info

引用次数: 0