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Airborne microbial flora in buffalo farms in a Mediterranean climate 地中海气候下水牛农场的空气微生物菌群
Translational Medicine Reports Pub Date : 2019-05-27 DOI: 10.4081/TMR.8146
D. Stelitano, G. Squillaci, B. Santella, A. Chianese, V. D’Oriano, E. Finamore, M. Vitiello, Federica Maria Di Lella, M. Galdiero, G. Franci
{"title":"Airborne microbial flora in buffalo farms in a Mediterranean climate","authors":"D. Stelitano, G. Squillaci, B. Santella, A. Chianese, V. D’Oriano, E. Finamore, M. Vitiello, Federica Maria Di Lella, M. Galdiero, G. Franci","doi":"10.4081/TMR.8146","DOIUrl":"https://doi.org/10.4081/TMR.8146","url":null,"abstract":"The last few decades have seen an increase in intensive buffalo farms worldwide. Such industrialized activity entails human and animal potential health-related hazards as well as for the environment. Given the breadth of the issue, in this study we focused on gathering microbiological air sampling in the Southern Italian buffalo farms in order to obtain further information on airborne microbial flora. In details, we evaluated the bio-aerosol concentration of cultivable bacteria and fungi in ten different buffalo farms. There are evidences showing that exposure to organic dust may exacerbate asthma, just as it may cause mucous membrane irritation and chronic bronchitis. Likewise, studies show that inhaling noninfectious microorganisms and their components may cause inflammation of the respiratory tract. As a result, this is a significant health hazard to these farms’ workers as well as to rural residents living closely to them.","PeriodicalId":443874,"journal":{"name":"Translational Medicine Reports","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116862901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Antibacterial and antiviral potential of neuropeptides 神经肽的抗菌和抗病毒潜力
Translational Medicine Reports Pub Date : 2019-05-13 DOI: 10.4081/TMR.8142
C. Zannella, D. Stelitano, V. Folliero, Luciana Palomba, T. F. Bovier, Roberta Astorri, A. Chianese, M. Monda, M. Galdiero, G. Franci
{"title":"Antibacterial and antiviral potential of neuropeptides","authors":"C. Zannella, D. Stelitano, V. Folliero, Luciana Palomba, T. F. Bovier, Roberta Astorri, A. Chianese, M. Monda, M. Galdiero, G. Franci","doi":"10.4081/TMR.8142","DOIUrl":"https://doi.org/10.4081/TMR.8142","url":null,"abstract":"The emergence of multidrug resistant bacteria is a global health threat and the discovery of new antimicrobial agents is an absolute priority. In this context endogenous peptides are emerging as novel potential candidates. In this work, we assessed the antimicrobial effects of orexins and ghrelin neuropeptides against gram-negative (Escherichia coli, Salmonella typhimurium, Klebsiella pneumoniae) and gram-positive (Staphylococcus aureus) bacteria. Orexin-B and ghrelin showed a potent bactericidal effect at concentration equal to or greater than 25 μg/ml. No antimicrobial activity has been observed for orexin-A. Furthermore, we investigated the antiviral proprieties of the three peptides against herpes simplex virus 1 (HSV-1). We found that orexin-B, but not orexin-A is effective for HSV-1 infectivity inhibition.","PeriodicalId":443874,"journal":{"name":"Translational Medicine Reports","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128058389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Relationship between type 2 diabetes and pancreatic cancer 2型糖尿病与胰腺癌的关系
Translational Medicine Reports Pub Date : 2018-11-19 DOI: 10.4081/TMR.7002
M. Yilmaz, A. Gürol
{"title":"Relationship between type 2 diabetes and pancreatic cancer","authors":"M. Yilmaz, A. Gürol","doi":"10.4081/TMR.7002","DOIUrl":"https://doi.org/10.4081/TMR.7002","url":null,"abstract":"Diabetes mellitus and cancer are conditions that constitute a serious problem for the health of the world’s population, and their co-existence in the same person is becoming increasingly common. Glucose metabolism and the presence of insulin in inflammatory situations appear to be the main factors driving this association, where hyperinsulinemia has been shown to contribute to an increase in risk of association between type 2 diabetes and cancer. Therefore, administering lower levels of exogenously administered insulin to patients with type 1 diabetes would decrease their risk of developing cancer when compared to patients with type 2 diabetes. The results from animal experiments seem promising in terms of pharmacological treatment.","PeriodicalId":443874,"journal":{"name":"Translational Medicine Reports","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122545979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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