S. Jazayeri, A. Rahimian, Maral Seyed Ahadi, S. Tavakolpour, S. Alesaeidi
{"title":"Neurologic Involvement in Granulomatosis with Polyangiitis: A Comparative Study","authors":"S. Jazayeri, A. Rahimian, Maral Seyed Ahadi, S. Tavakolpour, S. Alesaeidi","doi":"10.3390/iecbs2022-13963","DOIUrl":"https://doi.org/10.3390/iecbs2022-13963","url":null,"abstract":": Objective: The aim of this study was to describe the presentation and outcomes of patients with granulomatosis with polyangiitis (GPA) presenting with neurologic involvement according to ACR criteria. Methods: Consecutive newly diagnosed GPA patients who had undergone follow-up for at least six months between 2013 and 2018 at Amir-A’lam hospital, Tehran University of Medical Sciences, were retrospectively analyzed. Results: Patients were divided into two groups: those with nervous system involvement at either disease diagnosis or follow-up (89 patients) and those without neurological symptoms until the last follow-up (131 patients). From all patients reviewed in this study, 68 (30.9%) patients died during the follow-up period. Among the deceased patients, 18 (20.2%) were in the non-neurologic group, and 50 (38.2%) were in the neurologic group. The median (IQR) of BVAS in 220 patients was 11.0 (18.0-8.0) in total: 10.0 (14.5-7.50) and 12.0 (21.0-8.0) in the non-neurologic and the neurologic groups, respectively. The score of BVAS in the neurologic group was significantly higher than in the non-neurologic group ( p = 0.039). Of 131 patients, sensory neuropathy was found in 99 patients (75.5%). In total, 95 patients (72.5%) complained of hearing loss, which was diagnosed as sensory–neural hearing loss; 27 patients (20.6%) complained of headache; 13 (9.9%) had a history of cerebrovascular events; 5 (3.8%) had an episode of seizure or loss of consciousness (LOC); and 3 (2.3%) had mononeuritis multiplex. Two patients (1.5%) were diagnosed with meningitis and two (1.7%) with encephalitis. Conclusion: According to this study, neurological symptoms are an undeniable part of the disease course for GPA patients, and these symptoms are associated with disease severity, prognosis, and response to treatment.","PeriodicalId":433679,"journal":{"name":"The 3rd International Electronic Conference on Brain Sciences","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126302996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Food-Finding Test Paradigm without Deprivation Delays the Ethogram but Preserves the Olfactory Signatures in Female Mice with Normal and AD-Pathological Aging and Detects Their Ethogram Derangement Due to Social Isolation","authors":"Daniela Marín-Pardo, L. Giménez-Llort","doi":"10.3390/iecbs2022-13741","DOIUrl":"https://doi.org/10.3390/iecbs2022-13741","url":null,"abstract":"","PeriodicalId":433679,"journal":{"name":"The 3rd International Electronic Conference on Brain Sciences","volume":"35 11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121158083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ashley B. Durbin, Matthew R. Rodgers, James Robert Brašić
{"title":"Tic Reduction Following Heat-Induced Dehydration in Gilles de la Tourette Syndrome (TS)","authors":"Ashley B. Durbin, Matthew R. Rodgers, James Robert Brašić","doi":"10.3390/iecbs2022-13505","DOIUrl":"https://doi.org/10.3390/iecbs2022-13505","url":null,"abstract":"","PeriodicalId":433679,"journal":{"name":"The 3rd International Electronic Conference on Brain Sciences","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114550001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intrinsic and Extrinsic Factors in the Bizarre Patterns Elicited in the Open-Field Test in Male and Female Mice with Normal and AD-Pathological Aging under Social or Isolated Housing Conditions","authors":"L. Giménez-Llort, Miguel Llauradó-Sánchez","doi":"10.3390/iecbs2022-13506","DOIUrl":"https://doi.org/10.3390/iecbs2022-13506","url":null,"abstract":"","PeriodicalId":433679,"journal":{"name":"The 3rd International Electronic Conference on Brain Sciences","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134330828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Resonance Leading to Unexpected and Sudden Aneurysmal Rupture","authors":"Y. Iwata, H. Ujiié","doi":"10.3390/iecbs2022-13023","DOIUrl":"https://doi.org/10.3390/iecbs2022-13023","url":null,"abstract":"","PeriodicalId":433679,"journal":{"name":"The 3rd International Electronic Conference on Brain Sciences","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115660962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Meta-Analysis of RNA-Seq Data Identifies Potent Biomarkers for Intellectual Disability Disorder (IDD)","authors":"Prekshi Garg, Farrukh Jamal, P. Srivastava","doi":"10.3390/iecbs2022-12945","DOIUrl":"https://doi.org/10.3390/iecbs2022-12945","url":null,"abstract":"","PeriodicalId":433679,"journal":{"name":"The 3rd International Electronic Conference on Brain Sciences","volume":"114 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122751914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Immigration and Logotherapy: Addressing Mental Health Problems among Muslim Immigrants in Europe","authors":"S. Rahgozar, L. Giménez-Llort","doi":"10.3390/iecbs2022-12937","DOIUrl":"https://doi.org/10.3390/iecbs2022-12937","url":null,"abstract":"","PeriodicalId":433679,"journal":{"name":"The 3rd International Electronic Conference on Brain Sciences","volume":"184 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115724209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}