Applications of RNA-Seq in Biology and Medicine最新文献

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Assessing Host-Pathogen Interaction Networks via RNA-Seq Profiling: A Systems Biology Approach 通过RNA-Seq分析评估宿主-病原体相互作用网络:系统生物学方法

Applications of RNA-Seq in Biology and Medicine Pub Date : 2021-10-13 DOI: 10.5772/intechopen.96706

Sudhesh Dev Sareshma, B. Subha

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引用次数: 1

Insights into Oropharyngeal Microbiota, Biofilms and Associated Diseases from Metagenomics and Transcriptomic Approaches 从宏基因组学和转录组学方法深入了解口咽微生物群、生物膜和相关疾病

Applications of RNA-Seq in Biology and Medicine Pub Date : 2021-10-13 DOI: 10.5772/intechopen.96449

R. Priyadarshini, K. Krishnan, R. Niranjan

{"title":"Insights into Oropharyngeal Microbiota, Biofilms and Associated Diseases from Metagenomics and Transcriptomic Approaches","authors":"R. Priyadarshini, K. Krishnan, R. Niranjan","doi":"10.5772/intechopen.96449","DOIUrl":"https://doi.org/10.5772/intechopen.96449","url":null,"abstract":"Oral cavity is an ecologically complex environment and hosts a diverse microbial community. Most of these organisms are commensals, however, on occasion, some have the potential to become pathogenic causing damage to the human host. Complex interactions between pathogenic bacteria, the microbiota, and the host can modify pathogen physiology and behavior. Most bacteria in the environment do not exist in free-living state but are found as complex matrix enclosed aggregates known as biofilms. There has been research interest in microbial biofilms because of their importance in industrial and biomedical settings. Bacteria respond to environmental cues to fine-tune the transition from planktonic growth to biofilm by directing gene expression changes favorable for sessile community establishment. Meta-approaches have been used to identify complex microbial associations within human oral cavity leading to important insights. Comparative gene expression analysis using deep sequencing of RNA and metagenomics studies done under varying conditions have been successfully used in understanding and identifying possible triggers of pathogenicity and biofilm formation in oral commensals.","PeriodicalId":416299,"journal":{"name":"Applications of RNA-Seq in Biology and Medicine","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121620944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Introductory Chapter: Applications of RNA-Seq Diagnostics in Biology and Medicine 介绍性章节：RNA-Seq 诊断在生物学和医学中的应用

Applications of RNA-Seq in Biology and Medicine Pub Date : 2021-10-13 DOI: 10.5772/intechopen.99882

I. Vlasova-St Louis

引用次数: 0