发布求助
文献互助 智能选刊 最新文献

Beyond LEO - Human Health Issues for Deep Space Exploration [Working Title]最新文献

筛选
英文 中文
Effects of Microgravity on Human Physiology 微重力对人体生理的影响
Beyond LEO - Human Health Issues for Deep Space Exploration [Working Title] Pub Date : 2020-02-05 DOI: 10.5772/intechopen.90700
S. Iwase, N. Nishimura, Kunihiko Tanaka, T. Mano
{"title":"Effects of Microgravity on Human Physiology","authors":"S. Iwase, N. Nishimura, Kunihiko Tanaka, T. Mano","doi":"10.5772/intechopen.90700","DOIUrl":"https://doi.org/10.5772/intechopen.90700","url":null,"abstract":"The effects of microgravity conditions on neurovestibular, cardiovascular, musculoskeletal, bone metabolic, and hemato-immunological systems are described. We discuss “space motion sickness,” sensorimotor coordination disor-ders, cardiovascular deconditioning, muscular atrophy, bone loss, and anemia/ immunodeficiency, including their causes and mechanisms. In addition to the previously described deconditioning, new problems related to microgravity, spaceflight-associated neuro-ocular syndrome (SANS), and structural changes of the brain by magnetic resonance imaging (MRI) are also explained. Our proposed countermeasure, artificial gravity produced by a short-arm centrifuge with ergometric exercise, is also described in detail, and we confirmed this system to be effective in preventing the abovementioned deconditioning caused by microgravity exposure.","PeriodicalId":409661,"journal":{"name":"Beyond LEO - Human Health Issues for Deep Space Exploration [Working Title]","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127432673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
Spaceflight-Associated Immune System Modifications 与太空飞行相关的免疫系统修改
Beyond LEO - Human Health Issues for Deep Space Exploration [Working Title] Pub Date : 2019-09-25 DOI: 10.5772/intechopen.88880
Jérémy Jeandel, Coralie Fonte, Gaetano Calcagno, J. Bonnefoy, S. Ghislin, S. Kaminski, J. Frippiat
{"title":"Spaceflight-Associated Immune System Modifications","authors":"Jérémy Jeandel, Coralie Fonte, Gaetano Calcagno, J. Bonnefoy, S. Ghislin, S. Kaminski, J. Frippiat","doi":"10.5772/intechopen.88880","DOIUrl":"https://doi.org/10.5772/intechopen.88880","url":null,"abstract":"Spaceflight is an adverse environment characterized by a unique combination of stressors affecting almost all physiological systems, including the immune system. Indeed, several studies have shown that about 50% of the astronauts have faced immunological troubles. Here, we will review how spaceflight affects immune cell development, innate as well as adaptive immunity, required to ensure an efficient protection of the host, with a particular focus on T and B cells. Indeed, to better appreciate the risks associated to future long-duration space missions and to develop pharmacologic or nutritional countermeasures allowing immune system protection, it is mandatory to fully understand how these cell types are affected by space conditions. Finally, we will compare immune changes observed in astronauts with those encountered in the elderly, thereby illustrating the societal interest of space research. with the same antigen on Earth. This showed that","PeriodicalId":409661,"journal":{"name":"Beyond LEO - Human Health Issues for Deep Space Exploration [Working Title]","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128777995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信