Asploro Journal of Pediatrics and Child Health最新文献

{"title":"A Preventable Cause of Hypotonia in Infants: Case Report of Two Infants with Vitamin B12 Deficiency","authors":"A. M, Saghir S, Kmari M, Ourrai A, Hassani A, Abilkassem R, A. A.","doi":"10.36502/2021/asjpch.6168","DOIUrl":"https://doi.org/10.36502/2021/asjpch.6168","url":null,"abstract":"Introduction: Innate deficits in the metabolism or transport of vitamin B12 are exceptional. The main cause of vitamin B12 deficiency in infants is secondary to maternal deficiency. Maternal deficiency can have a vegan diet, low socio-economic level (developing countries) and a high level of development with a poor diet) or digestive pathologies responsible for a lack of absorption. The clinical signs are not very specific (developmental delay, pallor, hypotonia, vomiting and diarrhoea), which explains the frequent delay in diagnosis. The pathophysiology of the neurological damage, which is still uncertain, is thought to be secondary to a defect in myelination with altered nerve conduction and cortical atrophy. The aim of this work is to underline the importance of raising awareness of vitamin B12 deficiency in order to avoid its profound neurological repercussions, especially as substitution treatment allows an improvement or a reversibility of the neurological damage and raises the question of the possibility of screening new-borns.\u0000Materials and Methods: We report the case of two infants aged 6 months and 10 months with hypotonia and psychomotor regression from an early age, whose biological examination revealed pancytopenia with a collapsed vitamin B12 level in both infants and both mothers.","PeriodicalId":388612,"journal":{"name":"Asploro Journal of Pediatrics and Child Health","volume":"2006 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128565961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short Term Survival of Extreme Preterm Newborns at 23–26 Weeks’ Gestation in a Middle East Modern Referral Maternity Hospital","authors":"A. Mansour, H. Salama, S. Alomar, S. Ahmed, N. Mahmoud, Ratheesh Paramban, Mohamed Mahma","doi":"10.36502/2021/ASJPCH.6167","DOIUrl":"https://doi.org/10.36502/2021/ASJPCH.6167","url":null,"abstract":"Background: Caring about ELBW newborns at the limit of viability is demanding with a high rate of mortality and long-term morbidity. Society expectations become high and persistent while health care coast inside NICU is very high.\u0000Objective: The purpose of this study is to examine the short-term survival (till discharge) of extremely low birth weight (ELBW) newborns at limits of viability 23–26 weeks gestation (WG) age in a large tertiary maternity hospital.\u0000Methods: A population-based retrospective study of babies born at 23–26 WG age over 3 years period.\u0000Results: Over the study period 2016 to mid-2018, a total of 283 ELBW newborns were delivered in our institute. Of those, 250 were admitted to NICU (88%). The number of newborns who survived till discharge from NICU was 174 (61.5%) while the rate of delivery room death was 33 newborns (11.75%). The survival rates during 2016–2018 period were 35%, 64%, 73%, and 81.4% for 23, 24, 25, and 26 WG respectively. 76 newborns (26.9%) of NICU admissions died before discharge. Most deaths occurred during the first two weeks of life (64%). The main cause of death inside the NICU during the first 2 weeks was respiratory failure, followed by infection.\u0000Conclusion: Counseling Parent using local data become more convincing and reflecting local experience. Short term survival rate of ELBW is comparable to those reported in the literature. The first two weeks are very crucial where the mortality rate is highest.","PeriodicalId":388612,"journal":{"name":"Asploro Journal of Pediatrics and Child Health","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124474111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Epidemiological and Clinical Profile of Sexually Abused Children: A Hospital-Based Study","authors":"A. Chiabi, J. Sama, Elvis Meten, Annick Tchouamou, S. K. Nolna, F. Dongmo, E. Mah, S. Nguefack, A. Bella, R. Mbu","doi":"10.36502/2021/ASJPCH.6166","DOIUrl":"https://doi.org/10.36502/2021/ASJPCH.6166","url":null,"abstract":"Introduction: Child sexual abuse is an extensive health and societal problem as even the lowest prevalence of child sexual abuse includes a huge number of victims who still need to be considered. Africa has the highest prevalence of child sexual abuse yet still with a paucity of literature on the subject matter.\u0000Objective: Describe the epidemiological and clinical profile of children victim of sexual abuse reported at the Yaounde Gynaeco-obstetric and Pediatric Hospital (YGOPH).\u0000Methods: A hospital based cross sectional descriptive study was conducted from January 1st, 2017 – December 31st, 2019 at the Yaounde Gynaeco-Obstetric and Pediatric Hospital. Consultation files were examined and identified cases of child sexual abuse (CSA) recruited. Epidemiological and clinical data of included participants were treated using a pre-established questionnaire. Collected data were entered and analysed using SPSS (Statistical Package for Social Sciences) software version 26.0 with p-values calculated following a one variable binomial sampling.\u0000Results: In total, data was assessed from 51,331 pediatric consultation files of which 127 cases of child sexual abuse met our inclusion criteria. The prevalence of child sexual abuse was 0.25%. Most victims of child sexual abuse were of the female gender (92%) from single parenting homes (36.8%) (p< 0.05) within two age groups < 5years (32.9%) and 10-15 years (32.9%). Perpetrators were in majority males (84%) of age ≥18 years (72.4%) and were persons known to the victims (73.7%) who proceeded by taking advantage of the victims’ trust. Vaginal penetration (57.9%) with vaginal lesions (59.2%) were the most encountered cases which were placed on highly active anti-retroviral prophylaxis however with poor clinical follow-up (35.5%) as the patients did not turn-up for their visits.\u0000Conclusion: Child sexual abuse though not addressed as a matter of urgency, yet it is a problem with a gradual upward trend in our community most especially as perpetrators are persons we are familiar with. Thus, a call for greater vigilance with regards to the guidance we leave our children with.","PeriodicalId":388612,"journal":{"name":"Asploro Journal of Pediatrics and Child Health","volume":"208 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124340567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sandifer Syndrome","authors":"J. Gómez","doi":"10.36502/2021/asjpch.6165","DOIUrl":"https://doi.org/10.36502/2021/asjpch.6165","url":null,"abstract":"Sandifer syndrome, named after neurologist Paul Sandifer, was first reported by Marcel Kinsbourne in 1962, who noted an upper gastrointestinal disorder that occurs in children and adolescents with neurological manifestations. Sandifer syndrome is a neurobehavioral disorder that causes a series of paroxysmal dystonic movements in association with gastroesophageal reflux and, in some cases, with hiatal hernia. It is characterized by esophagitis, iron deficiency anemia, and is often mistaken for a seizure of epileptic origin.","PeriodicalId":388612,"journal":{"name":"Asploro Journal of Pediatrics and Child Health","volume":"261 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122661380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Immediate Impact of the Novel Coronavirus (COVID-19) Pandemic on Adolescents with Severe Obesity - Another Pandemic","authors":"Matheson Be, Herdes Re, G. D., She We, Bruzoni M, Pratt Jsa, A. M","doi":"10.36502/2020/ASJPCH.6160","DOIUrl":"https://doi.org/10.36502/2020/ASJPCH.6160","url":null,"abstract":"Background: The impact of the novel coronavirus 2019 (COVID-19) on the health and well-being of adolescents with obesity is currently unknown. The shelter-in place (SIP) orders imposed disruptions in everyday routines for all persons, including youth with obesity. Obtaining real-time data could offer important information about how youth with severe obesity are faring in the midst of this global crisis. Hence, this cross-sectional study aims to assess the impact of the COVID-19 pandemic on health-related behavior changes in adolescent patients with severe obesity.\u0000Methods: Fifteen adolescents with severe obesity (M ± SD: 16.40 ± 1.67 years; 66.7% female; 40% Hispanic) and 19 parents (45.83 ± 6.98 years; 94.7% female; 47.4% Hispanic) receiving care at an adolescent bariatric surgery clinic at a university medical center participated (20% response). Participants completed an online survey about the impact of COVID-19 and SIP on: eating habits, physical activity, sleep, screen time, mood, and motivation for behavior change. Parents completed similar questions regarding the impact of SIP on their child’s health.\u0000Results: Descriptive analyses revealed adolescents reported varied sleep quality and quantity, later bedtimes, increased home-cooked and family meals, decreased takeout food consumption, and increased anxiety levels. Almost half reported increased snacking. Changes in physical activity were noted. Parent and adolescent responses were mostly aligned, with the exception of self-reported weight change.\u0000Conclusions: Adolescents with severe obesity are facing challenges in maintaining health-related behavioral goals during SIP. Providers should be prepared to discuss and manage the impact of COVID-19 on adolescent patients with obesity.","PeriodicalId":388612,"journal":{"name":"Asploro Journal of Pediatrics and Child Health","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115392169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}