Chinese Journal of Practical Surgery最新文献

Extruded splenic hilar lymph nodes dissection with retroperitoneal approach retrogressively in radical gastrectomy for gastric cancer 腹膜后入路挤压性脾门淋巴结清扫术在胃癌根治术中的应用

Chinese Journal of Practical Surgery Pub Date : 2009-12-28 DOI: 10.3760/CMA.J.ISSN.1006-9801.2009.12.006

W. Xiang-bin, Ren Ying-kun, Han Guang-sen

引用次数: 0

Clinical study of insulin resistance for patients after selective abdominal surgery 选择性腹部手术后胰岛素抵抗的临床研究

Chinese Journal of Practical Surgery Pub Date : 2009-04-01 DOI: 10.3760/CMA.J.ISSN.1008-6315.2009.04.030

Hong Chen, Fei Lı, Jian-guo Jia

{"title":"Clinical study of insulin resistance for patients after selective abdominal surgery","authors":"Hong Chen, Fei Lı, Jian-guo Jia","doi":"10.3760/CMA.J.ISSN.1008-6315.2009.04.030","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1008-6315.2009.04.030","url":null,"abstract":"Objective To investigate the relative factors of insulin resistance(IR)during elective abdominal surgery and the mechanism of IR induced by surgery.Methods Fourteen patients underging elective abdominal surgery were studied.Fasting blood glucose(FBG),fasting plasma insulin(FPI),plasma TNF-α,IL-6 and CRP were tested for elective surgery patients on the day before,during operation and on one day after surgery.Insulin resistance index(HOMA-IR)and the index of insulin secretion(HOMA-β)were ealculated with homeostasis model assessment(HOMA).Insulin receptor and GLUT4 mRNA expression in skeletal muscle were assessed before operation and at the end of operation by use of RT-PCR.Results Significant differences were found in fasting blood glucose (5.95±1.08)mmol/L vs(8.92±2.41)mmol/L,fasting plasma insulin(19.95±3.33)mU/L vs(25.44±5.36)mU/L,IL-6(33.98±5.01)ng/L vs(45.29±7.81)ng/L and plasma TNF-α(86.70±9.27)ng/L vs(114.46±15.33)ng/L during and after operation(P＜0.01).A significant elevation of HOMA-IR levels was found after operation compared with that before operation[(9.59±2.89)vs(4.111.86)](P＜0.001).However there wag no significant difference in HOMA-β among three points(groups)of time(P=0.103).The result of RT-PCR showed that the expression of GLUT4 in muscle of patients at the end of operation reduced significantly compared with preoperation(t=12.488,P＜0.001)but there was no significance in INSR mRNA expression(P=0.165).ISI showed negative correlation with opermive time(r=-0.736、P＜0.001),blooding during operating (r=-0.594、P=0.032)and post-operative TNF-α(r=-0.641、P=0.018).Conclusion Insulin resistance occurs in elective abdominal surgery patients.The defective site is at postreceptor.To shorten the operation time,control the intensity of surgery and reduce the bleeding is helpful for decreasing IR. \u0000 \u0000Key words: \u0000Insulin resistance; Homeostasis model assessment; GLUT4; Surgery","PeriodicalId":372887,"journal":{"name":"Chinese Journal of Practical Surgery","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116039870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnosis and treatment of chronic pancreatitis with mass in the head of the pancreas 慢性胰腺炎伴胰头肿块的诊断与治疗

Chinese Journal of Practical Surgery Pub Date : 1900-01-01 DOI: 10.3760/CMA.J.ISSN.1673-4203.2010.09.012

Jie Yin, Zhong-tao Zhang

{"title":"Diagnosis and treatment of chronic pancreatitis with mass in the head of the pancreas","authors":"Jie Yin, Zhong-tao Zhang","doi":"10.3760/CMA.J.ISSN.1673-4203.2010.09.012","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1673-4203.2010.09.012","url":null,"abstract":"Chronic pancreatitis (CP) with mass and pancreatic cancer are difficult to identify from the Clinical performance. Imaging methods in the diagnosis of the CP with mass play an important role, which is very helpful for the indications for surgery of the hands, of resectable pancreatic head tumor, and surgical options, as well as estimates of the difficulty of the surgery. At present, we have taken the CP with mass as a precancerous lesion of pancreatic cancer. Surgical strategy in CP with mass has been directed at the pancreatic head with a variety of tactics including pancreatoduodenectomy ( Whipple procedure with or without pylorus preservation) and partial resection of the pancreatic duct drainage( Frey operation, Beger operation ). Once the diagnosis of the CP with mass was confirmed surgical treatment should be performed by pancreatoduodenectomy, which by not only the pancreatic head mass was resected, the bile ducts and pancreatic ducts and obstruction of the duodenum were lifted, but also the potential causes of pancreatic cancer were ruled out. Pancreatoduodenectomy has great risk for the big mass of pancreatic head, but the partial head resection can be accomplished with relative safety. \u0000 \u0000Key words: \u0000Pancreatitis; Pancreatoduodenectomy","PeriodicalId":372887,"journal":{"name":"Chinese Journal of Practical Surgery","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134462668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thyroid carcinoma in children. 儿童甲状腺癌。

Chinese Journal of Practical Surgery Pub Date : 1900-01-01 DOI: 10.1001/jama.1963.03700100140053

I. Cancer.

引用次数: 0