Hippocampus - Cytoarchitecture and Diseases最新文献

筛选
英文 中文
Neural Circuits and Some New Factors Involved in Hippocampal Memory 海马记忆的神经回路及一些新因素
Hippocampus - Cytoarchitecture and Diseases Pub Date : 2022-01-12 DOI: 10.5772/intechopen.101309
Rui Jing, Qiujie Cai, Wen Li, Xinhua Zhang
{"title":"Neural Circuits and Some New Factors Involved in Hippocampal Memory","authors":"Rui Jing, Qiujie Cai, Wen Li, Xinhua Zhang","doi":"10.5772/intechopen.101309","DOIUrl":"https://doi.org/10.5772/intechopen.101309","url":null,"abstract":"Humans and other primates have memory, and the hippocampus plays a critical role in this process. The neural circuitry is one of the structural foundations for the hippocampus in exerting memory function. To understand the relationship between the hippocampus and memory, we need to understand neural circuits. Past research has identified several classical neural circuits involved in memory. Although there are challenges with the study of hippocampal neural circuits, research on this topic has continued, and some progress has been made. Here, we discuss recent advances in our understanding of hippocampal neural circuit mechanisms and some of the newly discovered factors that affect memory. Substantial progress has been made regarding hippocampal memory circuits and Alzheimer’s disease. However, it is unclear whether these novel findings regarding hippocampal memory circuits hold promise for human memory studies. Additional research on this topic is needed.","PeriodicalId":368733,"journal":{"name":"Hippocampus - Cytoarchitecture and Diseases","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134060949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The circRNA and Role in Alzheimer’s Disease: From Regulation to Therapeutic and Diagnostic Targets circRNA及其在阿尔茨海默病中的作用:从调节到治疗和诊断靶点
Hippocampus - Cytoarchitecture and Diseases Pub Date : 2022-01-12 DOI: 10.5772/intechopen.99893
Wen Li, Guohua Jin
{"title":"The circRNA and Role in Alzheimer’s Disease: From Regulation to Therapeutic and Diagnostic Targets","authors":"Wen Li, Guohua Jin","doi":"10.5772/intechopen.99893","DOIUrl":"https://doi.org/10.5772/intechopen.99893","url":null,"abstract":"Alzheimer's disease (AD) is a devastating neurodegenerative disorder and the most common form of dementia worldwide. Although the great progress on the prevention and treatment of AD, no effective therapies are available as yet. With the increasing incidence of AD, it has brought a growing burden to the family and society. Histopathologically, AD is characterized by the presence of myloid β (Aβ) plaques composed of Aβ and neurofibrillary tangles (NFTs) composed of hyperphosphorylated tau proteins, which lead to neuronal loss. However, the full spectrum of precise molecular mechanism that contribute to AD pathogenesis remains largely unknown. circular RNAs (circRNAs) are a novel class of endogenous non-coding RNAs that play a vital role in post-transcriptional regulation. Recent reports showed circRNAs to be an important player in the development of neurodegenerative diseases like AD. In this chapter, we review recent progress on understanding the role of circRNAs in AD, and many studies implicating specific circRNAs in the development of the disease. Moreover, we explore the potential promise of these findings for future diagnosis and treatment.","PeriodicalId":368733,"journal":{"name":"Hippocampus - Cytoarchitecture and Diseases","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131213271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信