Martina Grandinetti, Ludovica Nazzaro, R. Izzo, Michele, Vignali
{"title":"Clinical Verification of the Activity and Tolerability of Fitostimoline Vaginal Pessaries in Women with Hysterectomy: Randomized, Perspective, Monoscentric Study","authors":"Martina Grandinetti, Ludovica Nazzaro, R. Izzo, Michele, Vignali","doi":"10.29011/2577-2236.100143","DOIUrl":"https://doi.org/10.29011/2577-2236.100143","url":null,"abstract":"Objective: To evaluate the activity of Fitostimoline® pessaries in comparison to the standard of care in the treatment of women with hysterectomy. Methods: An observational, randomized, perspective study performed on 60 women where 30 women were treated with Fitostimoline® pessaries for 12 days after surgery and 30 women were treated with the standard of care. A first follow-up visit was performed at 12 +/3 days and a final followup visit was performed at 40 +/3 days. Results: At the first control, 45% of patients in the Fitostimoline® group reported no evidence of vaginal bleeding after surgery; instead, 41% in the control group reported such result. At the final visit, 79% patients reported no evidence of vaginal bleeding in the Fitostimoline® group, while 63% in the control group. The medial duration of minor vaginal bleeding in the Fitostimoline® group was 11.8 days, whilst for discrete vaginal bleeding the medial duration was 4 days. In the control group instead it was 12 days, whilst for discrete vaginal bleeding the medial duration was 8 days. Conclusion: The use of Fitostimoline® ovules after hysterectomy is effective in reducing the quantity of vaginal bleeding, regardless the menopausal status, surgical approach and type of indication to surgery. Obstetrics & Gynecology: Open Access Grandinetti M, et al. Gynecol Obstet Open Acc 5: 143. www.doi.org/10.29011/2577-2236.100143 www.gavinpublishers.com","PeriodicalId":368193,"journal":{"name":"Obstetrics & Gynecology: Open Access","volume":"42 6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122222297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Review on the Use of Hysteroscopy Tissue Removal System in Gynaecology","authors":"R. Gururaj","doi":"10.29011/2577-2236.100142","DOIUrl":"https://doi.org/10.29011/2577-2236.100142","url":null,"abstract":"Intrauterine pathologies have become the common cause of gynaecological visits. These pathologies, if not treated can increase the rates of infertility and the risk of endometrial cancer. Surgical resection of intrauterine pathologies including polyps, fibroids, and intracavitary lesions using resectoscopes or hysteroscopy has become the mainstay of treatment, but the removal of large lesions poses a significant challenge to the surgeon. Also, the accumulation of fibroid pieces, fluid overloads, and the need for additional surgeries make these procedures more complex and tiresome. Numerous innovations in endoscopic gynaecology technology have resulted in the availability of Hysteroscopy tissue removal systems or hysteroscopy morcellators. This minimally invasive procedure has proved to be an efficient and safe alternative to conventional hysteroscopy resection. The objective of this review was to explore the clinical evidence available for the use of Hysteroscopy tissue removal systems and determine their efficacy and safety in gynaecological practice. The structure, procedural details, and characteristics of commonly used hysteroscopy tissue removal systems were thoroughly studies. Clinical performance, safety, and efficacy of these systems in comparison to other techniques were also evaluated in several uterine abnormalities. After reviewing the published literature, we concluded that the hysteroscopy tissue removal systems were more effective and safe to treat a wide range of intrauterine pathologies. The minimal fluid deficit, simultaneous cutting, and suction of tissue fragments, reduced operating time and minimum need for additional procedures with hysteroscopy tissue removal systems make it an excellent and viable option for treating a wide spectrum of uterine abnormalities in both office and operative settings. Obstetrics & Gynecology: Open Access Gururaj R. Gynecol Obstet Open Acc 5: 142. https://www.doi.org/10.29011/2577-2236.100142 https://www.gavinpublishers.com/","PeriodicalId":368193,"journal":{"name":"Obstetrics & Gynecology: Open Access","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132971432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Smith, Leah Hong, M. Keerthy, Monica Lee-Griffith, Robyn Garcia, M. Shaman, G. Goyert
{"title":"Six Critically Ill COVID-19 Pregnant Patients at a Detroit Hospital: A Case Series","authors":"N. Smith, Leah Hong, M. Keerthy, Monica Lee-Griffith, Robyn Garcia, M. Shaman, G. Goyert","doi":"10.22541/au.159103653.39532576","DOIUrl":"https://doi.org/10.22541/au.159103653.39532576","url":null,"abstract":"Objective: To highlight treatment modalities, management, and outcomes of 6 critically ill Coronavirus 2019 (COVID-19) pregnant patients. Design: We present a case series of 6 pregnant patients with severe COVID-19 infection requiring admission into the intensive care unit. Setting: Urban educational facility in Detroit, Michigan. Population: Pregnant women between the ages of 18-37 years old who tested positive for COVID-19 and required intensive care interventions. Methods: This is a retrospective, single-center case series of pregnant women who were infected with COVID-19 and subsequently required critical care. Main Outcome Measures: Maternal and fetal outcomes were measured. Results: All women required intensive care unit intervention, with 5 requiring mechanical ventilation. The average length of intubation was 5.6 days and average length of stay was 10.8 days. There was 1 full-term delivery via cesarean section and 2 preterm deliveries. All neonates tested negative for COVID-19. All patients discharged home on room air. Conclusion: This case series adds to the expanding literature describing the complex care surrounding pregnant patients with severe COVID-19 pneumonia requiring intensive care management. As the pandemic continues we hope our experience and treatment modalities can contribute to future care of patients.","PeriodicalId":368193,"journal":{"name":"Obstetrics & Gynecology: Open Access","volume":"282 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131587483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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