SunKrist Clinical and Medical Case Reports Journal最新文献

{"title":"Reactive Nasal Inflammation: Current Pathophysiological and Therapeutic Approach.","authors":"","doi":"10.46940/scmcrj.02.1008","DOIUrl":"https://doi.org/10.46940/scmcrj.02.1008","url":null,"abstract":"The pathophysiology of processes that underlie the onset and progression of reactive nasal inflammatory conditions is very complex. These include a heterogeneous group of disorders, ranging from seasonal allergic rhinitis to nonallergic, persisting, refractory forms of chronic rhinosinusitis (CRS). About 400 million people worldwide are affected by allergic rhinitis and another 200 million are thought to be affected by nonallergic forms of nasal inflammation including CRS.","PeriodicalId":365087,"journal":{"name":"SunKrist Clinical and Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114728241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of a Boy with Idiopathic Mental Retardation: From Uneducable to Educable.","authors":"Aamir Jalal Al-Mosawi","doi":"10.46940/scmcrj.02.1007","DOIUrl":"https://doi.org/10.46940/scmcrj.02.1007","url":null,"abstract":"Abstract Background: Mental retardation has been recently called by the American Psychiatric Association “Intellectual disability”, despite that the World Health Organization is still using the term “Mental retardation” in its ICD-10 publication. It is a heterogeneous condition marked by generalized neurodevelopmental abnormalities associated with significant impairment in mental or intellectual functioning and adaptive behaviors that affect every day general living. Patients and methods: A comprehensive multi-factorial treatment approach was used to treat a boy with idiopathic (Moderate to severe) mental retardation who was uneducable with the main aim of making him more educable. Treatment courses included intramuscular citicoline, piracetam, cerebrolysin and oral pyritinol. Results: Treatment was successful in advancing the mental and cognitive functions of the patient and making the child perfectly educable. Conclusion: There is no single agent that is known to convert an educable mentally retarded child to perfectly educable. Idiopathic mental retardation is a heterogeneous condition and the use of multi-factorial therapeutic agents is suggested for its treatment.","PeriodicalId":365087,"journal":{"name":"SunKrist Clinical and Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120912478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ReadiGraft BLX Putty and ReadiGraft Bone Chips in the Treatment of Severe Osteoarthropathy in Hemodialysed Patient.","authors":"","doi":"10.46940/scmcrj.01.1005","DOIUrl":"https://doi.org/10.46940/scmcrj.01.1005","url":null,"abstract":"Abstract Osteoarticular complications are a major concern in patients treated with long-term hemodialysis, hemofiltration or continuous ambulatory peritoneal dialysis. Uremic chronic patients, treated for long periods of time (≥15 years) with hemodialysis, could develop a new kind of osteoarthropathy due to amyloidosis characterized by abnormal distribution of beta-2 microglobulin (B2M) in joint tissue. Deposits of B2M are responsible for several lesions, clinically evident in different pathologies, such as: carpal tunnel syndrome, spondylarthrosis, and hemodialysis osteoarthropathy.","PeriodicalId":365087,"journal":{"name":"SunKrist Clinical and Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128763581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metachronic Small Bowel Metastasis of a Squamous Cell Carcinoma of The Cervix.","authors":"","doi":"10.46940/scmcrj.01.1004","DOIUrl":"https://doi.org/10.46940/scmcrj.01.1004","url":null,"abstract":"Clinical Image We report a case of a woman 33 years old with past medical fact of hypertension, in whom squamous cell carcinoma of the cervix was diagnosed within post coital bleeding. The tumor was classified stage Ib according to FIGO classification and were treated with brachytherapy followed by hysterectomy with oophorectomy and external iliac lymphadenectomy. The evolution was favorable and she remained asymptomatic for 3 years. She was than hospitalized for obstructive syndrome. Abdominal X ray showed hydro-aeric levels and abdominal computed tomography showed grelic tumor with distension of the small bowel.","PeriodicalId":365087,"journal":{"name":"SunKrist Clinical and Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115170393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rifampicin Induced Hyperbilirubinemias: A Case Report.","authors":"Rohit Bangwal, Jagdish Rawat, Dev Singh Jangpani","doi":"10.46940/scmcrj.01.1003","DOIUrl":"https://doi.org/10.46940/scmcrj.01.1003","url":null,"abstract":"Abstract Anti-tubercular therapy (ATT) induced hepatitis is a major problem which a physician encounters in his clinical practice. A case of 28-year old female, weighing 45 kg was brought to hospital with the chief complains of low-grade fever for the past two months, cough, shortness of breath and 4-5 kg weight loss in two months. She had no history of hypertension (HTN), diabetes mellitus (DM), pulmonary tuberculosis (PTB). Her Chest X-ray showed right sided bilateral pulmonary TB and sputum acid fast bacilli (AFB) smear was repeatedly positive. Pulmonologist has started Category-I anti-tubercular regimen (Rifampicin, Isoniazid, Pyrazinamide and Ethambutol) under DOTS as per RNTCP guidelines. After 7 days of starting the treatment (DOTS regimen), she noticed yellowish discoloration of sclera, orange discoloration of urine but in spite of this she continued the drug for a further two weeks. Patient was found to be developing hepatotoxicity with the findings of elevated total bilirubin (10.2 mg/dl), conjugated bilirubin (2.5 mg/dl) and unconjugated bilirubin (7.2 mg/dl). Viral markers for hepatitis including hepatitis B viruses (HBsAg), hepatitis C viruses (HCV), human immunodeficiency virus (HIV), were all are non-reactive. Pulmonologist made provisional diagnosis of anti-tubercular drugs (specially rifampicin) induced hyperbilirubinemias. Pulmonologist initially hold Rifampicin and Pyrazinamide, but started Isoniazid, Ethambutol, Ofloxacin, Pyridoxine along with liver enzyme. She showed gradual improvement as bilirubin after one-week had dropped down to 1.2 mg/dl. Rifampicin was added to the regimen and the serum bilirubin checked after 1 week was found 1 mg/dl. Pyrazinamide was added after repeated LFTs showed normal values. Patient continued her drugs and came for review after three months. She was advised to continue and complete the course of anti-tubercular drugs. Since Rifampicin is the most important first line anti-tubercular drug it is very important to restart this drug in order to have a satisfactory response to anti-tubercular therapy. We have reported this case because of its rarity in clinical practice. As a health care team member clinical pharmacist are need to be made aware of these potentially fatal adverse effects associated with anti-tubercular therapy via conduction of quality-based seminars, published medical literature, conferences, learning programs and health care camps.","PeriodicalId":365087,"journal":{"name":"SunKrist Clinical and Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115242450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coffin Siris Syndrome with Significant Autistic Features.","authors":"Aamir Jalal Al-Mosawi","doi":"10.46940/scmcrj.01.1002","DOIUrl":"https://doi.org/10.46940/scmcrj.01.1002","url":null,"abstract":"Abstract Coffin Siris Syndrome is a rare genetic dysmorphic disorder that was first described by Coffin and Siris in 1970. It is associated with mental retardation and distinctive coarse facial features including wide nose, wide mouth with thick everted upper and lower lips, thick eyebrows and lashes, hirsutism/hypertrichosis. Sparse scalp hair particularly in the temporal areas. Coffin Siris syndrome has been reported only once in Iraq. The first Iraq patient with Coffin Siris syndrome (Al Mosawi AJ,2006) was also the first patient in the Arab. The occurrence of significant autistic features in form of pervasive developmental disorder or autism has been very infrequently reported in association with Coffin Siris syndrome. This aim to report which is most probably the seventh case of Coffin Siris Syndrome associated with significant autistic features. The case is the second case of this syndrome in Iraq which is also the case number 170 in the world.","PeriodicalId":365087,"journal":{"name":"SunKrist Clinical and Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123590790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Despite the Advances in Dentistry, Why Do Children Have Tooth Decay?","authors":"M. Karimi","doi":"10.46940/scmcrj.01.1001","DOIUrl":"https://doi.org/10.46940/scmcrj.01.1001","url":null,"abstract":"Editorial Nowadays, oral problems are one of the most common problems of people around the world, especially among children. Of course, it may seem that with the advancement of health status, the level of tooth decays and loss of teeth is much less than in the past, but with regard to the types of nutrition, misconceptions and the inadequate use of oral hygiene instructions, unfortunately, dental problems still exist and somehow it seems the conditions of oral hygiene among children has gotten worse. Dr. Alvin Dannenberg says that the cause of our children's tooth decay is not a lack of fluoride. The reason for the gingival bleeding in children is not lack of tooth brushing or not using dental floss. The main causes of this condition are the lack of nutrition, the consumption of acidic and sweet drinks, the disruption of the healthy intestinal bacteria and their inactive lifestyle [1]. In addition to brushing and flossing, he believes four other criteria should be considered. Having healthy bacteria in the intestine, reinforce healthy bacteria in the children's saliva, and makes them function naturally in the mouth. As a result, it helps prevent dental caries and gum disease [1]. Avoiding the use of refined carbohydrates is another way of preventing the spread of unhealthy bacteria and helping to maintain acid concentration at a healthy level in the mouth. In addition, parents should place the essential nutrients and minerals in the diet of children [1]. Finally, parents should advocate active living and playing outdoors [1]. The statistics of dental caries in children are very high due to the statistics observed from different sources. According to my experiences, I have been suffering from the spreading of dental caries in young children. Even children between the ages of 2 and 3 are involved with this issue.","PeriodicalId":365087,"journal":{"name":"SunKrist Clinical and Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115789456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disymptomatic Wiskott Aldrich Syndrome: Overcoming a Diagnostic Challenge.","authors":"Aamir Jalal Al-Mosawi","doi":"10.46940/scmcrj.01.1006","DOIUrl":"https://doi.org/10.46940/scmcrj.01.1006","url":null,"abstract":"Abstract Background: There are three main forms of the Wiskott Aldrich syndrome, the classic severe form, the disymptomatic form without cutaneous signs (Harzheim and colleagues, 1965) and a milder variant X-linked thrombocytopenia and neutropenia. The aim of this paper is to describe the very rare occurrence of disymptomatic form of Wiskott Aldrich syndrome in two Iraqi brothers and the diagnostic challenge associated with such cases. Patients and methods: The case of two Yezidis brothers referred because each boy had two different medical reports from Hevi Teaching Children Hospital in Dohuk, Kurdistan Iraq. Two of these medical reports recommended sending them outside Kurdistan or outside Iraq for the diagnosis and management of their illnesses. Each of these medical reports was signed by a committee that included four consultant doctors. Results: The two brothers had chronic illness of more than two years duration characterized by thrombocytopenia, leucopenia, splenomegaly, draining ear (more prominent in the older brother) and chronic liver disease (more prominent in the younger bladder). The parents were consanguineous. The father was apparently healthy, but the mother was having allergic skin disorder. The boys had an older brother who died at the age of thirteen. The two patients have four healthy sisters aged 18, 15, 10 and 8 years respectively. Conclusion: This paper demonstrates that when it comes to the diagnostic challenges associated with rare disorders, obscurity, uncertainty and complexities can be transformed to a crystal-clear diagnosis in the hands of the expert.","PeriodicalId":365087,"journal":{"name":"SunKrist Clinical and Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134010254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}