Abdullah Al Mamun, A. Maqbool, F. Sohael, Arifur Rahman, Majedul Islam, Takeru Shima, N. Shimojo, S. Kawano, N. Yamaguchi, M. Moroi, S. Jesmin
{"title":"Prevalence of Diabetes Mellitus among Tuberculosis patients in Bangladesh","authors":"Abdullah Al Mamun, A. Maqbool, F. Sohael, Arifur Rahman, Majedul Islam, Takeru Shima, N. Shimojo, S. Kawano, N. Yamaguchi, M. Moroi, S. Jesmin","doi":"10.33425/2639-9326.1099","DOIUrl":"https://doi.org/10.33425/2639-9326.1099","url":null,"abstract":"Aim: Tuberculosis (TB) and diabetes mellitus continue to be significant public health problems. Diabetes screening of tuberculosis patients will provide early case diagnosis, improved diabetes control, and improved tuberculosis treatment result. The purpose of this study was to ascertain the prevalence and risk factors for diabetes in tuberculosis patients, as well as their influence on the treatment result of tuberculosis. Methods: This cross-sectional study was conducted at Bangladesh's randomly chosen peripheral health institutions. All TB patients above the age of 18 years were checked for diabetes. Age, gender, family history, smoking, and BMI were all considered as risk factors. Results: Out of 165 participants, diabetes was shown to be prevalent in 35% of TB patients. Diabetes was related to advanced age and type of tuberculosis; its origin (pulmonary or extra pulmonary) and socioeconomic level were found to be significant. Conclusion: Diabetes is a common comorbidity among tuberculosis patients. Over the age of 50 years, the risk of this twin morbidity increases significantly. Screening tuberculosis patients for fasting blood sugar values will aid in the early diagnosis of diabetes and will lead to a better prognosis.","PeriodicalId":360691,"journal":{"name":"Diabetes & its Complications","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125444925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tabarak Sh Abadi, Maryam T Ibrahim, A. S. Ahmed, P. Tahir
{"title":"Evaluation of Diabetes Mellitus in Diabetic Patients in a Correlation Between Body Mass Index and Blood Sugar","authors":"Tabarak Sh Abadi, Maryam T Ibrahim, A. S. Ahmed, P. Tahir","doi":"10.33425/2639-9326.1100","DOIUrl":"https://doi.org/10.33425/2639-9326.1100","url":null,"abstract":"Background: Body mass index (BMI) criteria are currently the primary focus in obesity treatment recommendations, with different treatment cutoff points based upon the presence or absence of obesity-related comorbid disease. Aim: This project aimed to explore the relationship of body mass index with blood sugar. Patients & methods: Seventy-one adult diabetic patients (36 males+35 females) were subjected to this study. Body mass index was calculated for each patient and random blood sugar was also measured. Results: The highest mean value of BMI was among male & female patients in the age group 60-69 years old, which reached 36.57 & 32.74, respectively while the mean value of random blood sugar in males was among the age group 30-39 years which reached 258.88 mg/dL. But it was 295.0mg/dL among age group >70years in females. Conclusion: It is concluded that obesity is an important risk factor for diabetes and there was a relationship between BMI and increased blood sugar","PeriodicalId":360691,"journal":{"name":"Diabetes & its Complications","volume":"176 11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114081451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hypoglycemia and Dementia: Is Alzheimer's Disease a Consequence of Sugar Deficiency?","authors":"A. Gelbard","doi":"10.33425/2639-9326.1101","DOIUrl":"https://doi.org/10.33425/2639-9326.1101","url":null,"abstract":"This next essay will bring proof of reductions in cerebral glucose metabolism found in AD patients, possibly indicating that AD stems from Glucose insufficiency. It would later counter this assumption by showing the extremely high prevalence of AD among diabetics, and then, solve the mystery by proving that what's causing the dementia among diabetics is actually avoiding sugar according to doctor's orders. It will prove it by showing an unbreakable link between hypoglycemic (hypo, not hyper) events in diabetics and the risk of developing Alzheimer's disease. It's therefore will prove that AD in fact stems from lack of glucose consumption over the years and would suggest glucose as a possible treatment to AD patients.","PeriodicalId":360691,"journal":{"name":"Diabetes & its Complications","volume":"111 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127935162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Burlina, M. Dalfrà, S. Visentin, Silvia Pastrolin Annunziata Lapolla
{"title":"The Impact of COVID-19 Pandemia during the First Lockdown Period on Gestational Diabetes Mellitus: A Retrospective Single Centre Evaluation","authors":"S. Burlina, M. Dalfrà, S. Visentin, Silvia Pastrolin Annunziata Lapolla","doi":"10.33425/2639-9326.1102","DOIUrl":"https://doi.org/10.33425/2639-9326.1102","url":null,"abstract":"Data on the impact of COVID-19 on diagnosis, management and outcomes of women with GDM are few. Our aim was to evaluate the possible impact of lockdown on GDM diagnosis and follow-up. We retrospectively analyzed the GDM diagnostic modalities, the clinical-metabolic characteristics and the maternal and fetal outcomes in 48 GDM women followed during the lockdown (March-May 2020) and to compare the results with the 61 GDM women followed in the same period in 2019. We found no significant differences between the two groups in terms of diagnosis, clinical-metabolic characteristics and maternal and fetal outcomes. Therefore, we found that lockdown did not affect negatively maternal and fetal outcomes of GDM patients followed in this period.","PeriodicalId":360691,"journal":{"name":"Diabetes & its Complications","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132322018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antioxidant and Hepatoprotective Activity of Leaf Extract of Smilax Anceps Wild","authors":"Shorinwa Olusayo A, Shatange Dorothy D","doi":"10.33425/2639-9326.1098","DOIUrl":"https://doi.org/10.33425/2639-9326.1098","url":null,"abstract":"Introduction: Smilax anceps leaf is used for general healing of the body in traditional medicine. The aim of this study was to investigate the in-vitro antioxidant potential and in-vivo hepatoprotective activity of the ethanol leaf extract of Smilax anceps against carbon tetrachloride induced hepatotoxicity. Materials and Methods: Preliminary phytochemical screening and acute toxicity were determined. In-vitro antioxidant activity of the plant was evaluated using 2, 2-diphenyl-1-picryl-hydrazyl (DPPH), reducing power activity, nitric oxide scavenging, and lipid peroxidation scavenging activity assays. In- vivo hepatoprotective activity was determined using albino rats, divided into groups of six comprising of 5 animals each vis the control, CCl4, extract 250,500 and 1000mg/kg, and silymarin 100mg/kg. Treatments were done for seven days and carbon tetrachloride dissolved in olive oil was administered on the seventh day. Biochemical analysis was performed to assay the levels of aspartate aminotransferase (AST), alanine amino transaminase (ALT), alkaline phosphatase (ALP), albumin (ALB), total protein (TP) and Total bilirubin (TB) with histological examination of the liver. Phytochemical screening showed the presence of saponins, flavonoids, tannins, carbohydrates and steroids/ terpenoids. Results: The extract showed significant (P<0.01) scavenging activity against DPPH, reducing power activity, nitric oxide scavenging, and lipid peroxidation. There was a statistically significant (P<0.05) decrease in total bilirubin (TB), alanine amino transaminase (ALT) and alkaline phosphatase (ALP). Conclusion: The findings of this study showed that the ethanol leaf extract of S. anceps possesses significant antioxidant and hepatoprotective which might be due to the presence of flavonoids.","PeriodicalId":360691,"journal":{"name":"Diabetes & its Complications","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116659489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}