{"title":"Characteristics of Oxygen-Dependent Processes in Pulmonary Tuberculosis and Their Dynamics in the Course of Complex Treatment","authors":"Shafer Yu. A","doi":"10.54026/gjid/1006","DOIUrl":"https://doi.org/10.54026/gjid/1006","url":null,"abstract":"In conditions of tuberculous inflammation, decompensation occurs in the system of peroxidation – antioxidant protection, in which the mechanisms of oxygen transport by blood play an important role. Many pathogenetic links in the development of Tuberculosis (TB) lungs insufficiently studied, in particular, of blood Oxygen Carrying (OC) of blood.","PeriodicalId":352901,"journal":{"name":"Global Journal of Infectious Disease (GJID)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130453036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Detection of The Virus and Antibodies of SARS-Cov-2 from Healthy Indonesian Volunteers In 2020: Analysis Using Qualitative and Quantitative Methods","authors":"Laura Navika Yamani","doi":"10.54026/gjid/1005","DOIUrl":"https://doi.org/10.54026/gjid/1005","url":null,"abstract":"Individuals with COVID-19 and no symptoms, known as asymptomatic carriers, are found mostly in the community. Testing is very important to help reduce the spread of COVID-19. This study aimed to detect virus and antibodies of SARSCoV-2 in healthy Indonesian volunteers. In September 2020, 45 healthy volunteers participated were taken nasopharyngeal/ oropharyngeal swabs to detect the virus SARS-CoV-2 using RT-PCR, and blood samples to detect antibodies qualitatively by three rapid tests (Vazyme, Clugene, and RIGHA kits) and quantitatively by ELISA tests. Among healthy volunteers, COVID-19 asymptomatic carriers who have RT-PCR positive were 16% (7/45) with average of Ct 36.14. The seroprevalence of total SARS-CoV-2 antibodies (IgM and/or IgG) in RT-PCR positivity (asymptomatic carriers) detected by vazyme, clugene and RIGHA kits was 86%, 76% and 52%, respectively and was higher than the negative group (34, 21 and 24%). SARS-CoV-2 IgG antibody titers in the group that were positive for IgM and/or IgG (detected in at least one rapid test) by ELISA was averaged 109.76 ± 114.14 BAU/ml and significantly higher in negative group with titer of 11.45 ± 9.87 BAU/ ml. High titer of SARS-CoV-2 IgG anti-RBD antibodies was resulted in consistent positive in three rapid tests (vazyme, clugene, and RIGHA) compared to lower titer. Our findings suggest that healthy individuals with virus and/or antibodies of SARS-CoV-2 may have been infected recently or in the past. Antibody-positive results detected in healthy volunteers by three rapid tests were more common in asymptomatic carriers, and had higher titer antibody","PeriodicalId":352901,"journal":{"name":"Global Journal of Infectious Disease (GJID)","volume":"22 6S 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115946024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Knowledge and Perception of COVID-19 Related Social Distancing Regulations: A Cross-Sectional Study of Bangladeshis Living in Bangladesh and the United States","authors":"Sonica Sayam","doi":"10.54026/gjid/1004","DOIUrl":"https://doi.org/10.54026/gjid/1004","url":null,"abstract":"This study compared the Perception of Social Distancing Regulations (PSDR) among Bangladeshis living in Bangladesh (BD) and the United States (US). Methods: Data were collected through a cross-sectional survey (n = 2338; BD=1879, US=459) using social media platforms during June and July 2020. Based on the responses, ‘Perception Scores’ with values ranging from 0-9 were assigned. Using SAS 9.4, bivariate analyses and ordinal logistic regression were conducted to investigate the relationship between PSDR and Sociodemographic Characteristics (SDCs). Results: Bivariate analyses showed PSDR is significantly related with highest level of education among participants from the U.S. (p=0.002) and BD (p<0.0001); household income (p=0.001) and area of residence (p=0.002) among the participants of BD. Ordinal logistic regression revealed significant effect of education but no effect of household income in predicting higher PSDR score. Conclusion: In a population of the same ethnic origin, the role of SDCs varies in predicting the COVID-19 related PSDR score based on their current primary country of residence","PeriodicalId":352901,"journal":{"name":"Global Journal of Infectious Disease (GJID)","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126459716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antiretroviral Therapy: A Compendium of the Evolving Treatment Paradigm for HIV infection","authors":"N. Gamad","doi":"10.54026/gjid/1003","DOIUrl":"https://doi.org/10.54026/gjid/1003","url":null,"abstract":"Guidelines on Antiretroviral Therapy (ART) are updated regularly and it is important to be abreast with the increasing knowledge. Recent international recommendation suggests initiating the ART to all those individuals who have detectable viremia. While it is imperative to perform baseline CD4+ counts, viral loads and resistance testing before starting treatment, non-availability of any of these tests should not delay treatment initiation. Currently, ART in the form of daily administered triple-drug combination therapy consisting of 2 NRTIs plus 1 INSTI/PI/NNRTI, is recommended for newly diagnosed patients. The regimen should be selected based on virological efficacy, adverse effects, drug-drug interactions and cost. This article is an attempt to give an overview of existing and upcoming antiretroviral drugs and recent recommendations in the management of people living with human immunodeficiency virus infection.","PeriodicalId":352901,"journal":{"name":"Global Journal of Infectious Disease (GJID)","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116642737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}