Medical Imaging - Principles and Applications [Working Title]最新文献

{"title":"The Application of Functional Magnetic Resonance Imaging in Neuropathic Pain","authors":"Zhi Dou, Li-qiang Yang","doi":"10.5772/intechopen.89200","DOIUrl":"https://doi.org/10.5772/intechopen.89200","url":null,"abstract":"In the past, neuropathic pain has been lacking in ideal imaging research methods, which not only limits our research on the pathogenesis of neuropathic pain but also seriously affects the prognosis of treatments. With the rapid development of fMRI technology, more and more scholars have begun to use fMRI technology in the study of neuropathic pain in recent years. This provides a new idea for revealing the underlining mechanisms of neuropathic pain and improving the clinical treatment concepts. In this chapter, we summarized the recent studies of fMRI in neuropathic pain so that readers can better understand the research status and future research directions.","PeriodicalId":351674,"journal":{"name":"Medical Imaging - Principles and Applications [Working Title]","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121661995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research in Medical Imaging Using Image Processing Techniques","authors":"Dr. Yousif Mohamed Yousif Abdallah, Tariq Alqahtani","doi":"10.5772/INTECHOPEN.84360","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.84360","url":null,"abstract":"Medical imaging is the procedure used to attain images of the body parts for medical uses in order to identify or study diseases. There are millions of imaging procedures done every week worldwide. Medical imaging is developing rapidly due to developments in image processing techniques including image recognition, analysis, and enhancement. Image processing increases the percentage and amount of detected tissues. This chapter presents the application of both simple and sophisti-cated image analysis techniques in the medical imaging field. This chapter also summarizes how to exemplify image interpretation challenges using different image processing algorithms such as k-means, ROI-based segmentation, and watershed techniques.","PeriodicalId":351674,"journal":{"name":"Medical Imaging - Principles and Applications [Working Title]","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132458014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal Changes of Structural and Functional Connectivity and Correlations with Neurocognitive Metrics","authors":"Yongxia Zhou","doi":"10.5772/INTECHOPEN.86641","DOIUrl":"https://doi.org/10.5772/INTECHOPEN.86641","url":null,"abstract":"Revealing brain functional and micro-structural changes over a relatively short period at individual levels are especially important given that many risks associated with age including vascular and neuroinflammation increases and could confound the baseline fMRI parametric images. Cellular-level axonal injury and/or demyelination as well as dispersed mesoscopic level substance abnormal aggregation and structural/functional abnormality could occur in short subacute/acute phases, while literatures related to longitudinal changes with age are limited with only our previous fMRI findings. Longitudinal data were used to characterize these multi-parameters including random intercept and interval per individual. No significant age by gender interactions have been found to either DTI fractional anisotropy (FA) or diffusivity metrics. The interval effective regions showed longitudinal change of FA and radial diffusivity (RD)/axial diffusivity (AX) values remained similar to the aging results found with cross-sectional data. Significant correlations between DTI and fMRI metrics as well as between imaging and neurocognitive data including speed and memory were found. Our results indicate significant and consistent age, gender and apolipoprotein E (APOE) genotypic effects on structural and functional connectivity at both short-interval and cross-sectional ranges, together with correlational neurocognitive functions. We found longitudinal changes in both DTI and fcMRI in regions were similar to those demonstrating cross-sectional effects of age; for instance decreased fcMRI in DMN but increased fcMRI in anti-correlated DAN networks. The APOE genotypic signatures of FA and functional connectivity suggested possible tight associations between myelin/neuronal activation and APOE gene, indicating different roles of APOE alleles on brain structural conductivity, demyelination and neuroplasticity. Taken together, our neuroimaging and correlational neurocognitive results indicate significant and consistent age, gender and APOE genotypic effects on structural and functional connectivity at both baseline and longitudinal short-interval ranges.","PeriodicalId":351674,"journal":{"name":"Medical Imaging - Principles and Applications [Working Title]","volume":"366 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134405942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}