SOJ Neurology and Neuroscience最新文献

Neuroscience 神经科学

SOJ Neurology and Neuroscience Pub Date : 1900-01-01 DOI: 10.53902/sojnn.2022.02.000508

Gilson de Abreu Viza Junior

引用次数: 0

Covid-19, Carnosine and Cognition Covid-19、肌肽与认知

SOJ Neurology and Neuroscience Pub Date : 1900-01-01 DOI: 10.53902/sojnn.2021.01.000506

A. Hipkiss

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The Role of Mutations on Genes KRT3 & KRT12 in Meesmann Corneal Dystrophy Syndrome KRT3和KRT12基因突变在Meesmann角膜营养不良综合征中的作用

SOJ Neurology and Neuroscience Pub Date : 1900-01-01 DOI: 10.53902/sojnn.2022.02.000509

S. Asadi

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Dementia in Parkinson’s Disease: it’s Therapeutics 帕金森病中的痴呆:治疗学

SOJ Neurology and Neuroscience Pub Date : 1900-01-01 DOI: 10.53902/sojnn.2021.01.000501

A. Chakraborty

{"title":"Dementia in Parkinson’s Disease: it’s Therapeutics","authors":"A. Chakraborty","doi":"10.53902/sojnn.2021.01.000501","DOIUrl":"https://doi.org/10.53902/sojnn.2021.01.000501","url":null,"abstract":"Background: Dementia is a cognitive degenerative disease generally associated with Alzheimer disease, but victims with Parkinson’s disease also develops dementia at the latter stage. Dementia associates with irreversible loss of memory, and no medicinal cure is yet available. We here put some light on possible cell therapy for dementia. Aim: Neural stem cells are multipotent cells which are capable of self-replication and differentiation into neurons, astrocytes or oligodendrocytes in the central nervous system. They produce Dopamine, neural factors, and therefore, one can expect that NSC transplantation can ultimately provide a better therapeutic approach in the treatment of dementia as well as Parkinson’s disease (PD). Methods: We discussed the merits and demerits of using hNSCs cells over other possible candidate cells. Results: As we found that hNSCs can secrete Dopamine as well as some neurotropic factors, like Brain-Derived Neurotropic Factor (BDNF) and Glial cell-Derived Neurotropic Factors (GDNF) which can support the proliferation of hNSCS and its Dopamine production ability, hNSCs can supply dopamine and also can stop α-synuclein aggregation. Conclusion: hNSCs, therefore, could be a better cell regiment for cell transplantation therapy for dementia as well as PD.","PeriodicalId":350784,"journal":{"name":"SOJ Neurology and Neuroscience","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132831265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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A Simplified Overview of the Current Non-Surgical Treatment of Brain Tumor Patients with Special Emphasis on Its Complications. A Much Needed Contemporary Review Especially for Neurosurgeons 目前脑肿瘤非手术治疗的简单概述，特别强调其并发症。一个非常需要的当代评论，特别是对神经外科医生

SOJ Neurology and Neuroscience Pub Date : 1900-01-01 DOI: 10.53902/sojnn.2021.01.000507

A. Chaturbedi

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Significance of Cortical Micro-Infarcts in the Human Brain 人脑皮层微梗死的意义

SOJ Neurology and Neuroscience Pub Date : 1900-01-01 DOI: 10.53902/sojnn.2021.01.000503

J. De Reuck

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Impact of Patient Centred Care in a Dementia Ward in an Acute Hospital 以病人为中心的护理在急性痴呆病房的影响

SOJ Neurology and Neuroscience Pub Date : 1900-01-01 DOI: 10.53902/sojnn.2021.01.000502

L. Ching

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The 30 Top-Cited Articles on Os Odontoideum: A Bibliometric Study Odontoideum的30篇被引文章:文献计量学研究

SOJ Neurology and Neuroscience Pub Date : 1900-01-01 DOI: 10.53902/sojnn.2021.01.000504

Weixin Li

{"title":"The 30 Top-Cited Articles on Os Odontoideum: A Bibliometric Study","authors":"Weixin Li","doi":"10.53902/sojnn.2021.01.000504","DOIUrl":"https://doi.org/10.53902/sojnn.2021.01.000504","url":null,"abstract":"Objective: To evaluate the top 30 most-cited articles in the literature on os odontoideum. Methods: A search using the Web of Science database and the search phrase \"os odontoideum\" was conducted. The 30 most-cited articles on osodontoideum were analyzed. The study was performed in May 2020. We searched for articles published between 1920 and 2020. Articles were sorted and ranked according to the total number of citations. We evaluated the following information of each article, including first author, journal, title, number of citations, average citation per year, and author affiliation. Results: A total of 357 studies matched our search criteria, of which the top 30 most-cited ranged between 232 and 60 citations. The article by Dickman et al. published in Neurosurgery, was the most-cited article with a total citation of 232, followed by Dickman et al. with 221 and Smoker et al. with 179. Menezes was the most cited first authors, with 4 articles, followed by Dickman with 3 articles. Child's Nervous System, Journal of Neurosurgery, and Spine were three most frequent destination journals. Most of the articles originated from the United States (n=24) and University of Iowa Hospitals and Clinics published 6 articles and was the highest in the number of most-cited articles. Most of the articles focused on the clinical management of osodontoideum (83.3%). Conclusion: The current study confers a better understanding of current treatment strategies and the advances in the management of osodontoideum. It helps guide the clinical management and academic achievements.","PeriodicalId":350784,"journal":{"name":"SOJ Neurology and Neuroscience","volume":"128 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128107474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Paranoid Hostility but Not Depressive Symptoms Associated with Cytokines During the Premenstrual Phase in Young Women 年轻女性经前期偏执敌意而非抑郁症状与细胞因子相关

SOJ Neurology and Neuroscience Pub Date : 1900-01-01 DOI: 10.53902/sojnn.2021.01.000505

Syros Ioannis

{"title":"Paranoid Hostility but Not Depressive Symptoms Associated with Cytokines During the Premenstrual Phase in Young Women","authors":"Syros Ioannis","doi":"10.53902/sojnn.2021.01.000505","DOIUrl":"https://doi.org/10.53902/sojnn.2021.01.000505","url":null,"abstract":"It is well known that some women, during their premenstrual phase, express Hostility (Ho) and Depressive symptoms (De). Various studies indicate that Ho and De correlate with circulating concentrations of cytokines. These data support the hypothesis of an inflammation-sensitive mechanism linked to certain psychological states. The aim of this study was to correlate Ho and De with selective proinflammatory cytokines during the menstrual cycle in young women. Twenty-two physically healthy medical students, mean age 22.95+2.83(SD), were studied. All reported regular menses that ranged between 27-33 days. Blood was drawn three times across a single cycle: at follicular phase (FL), at mid luteal phase (ML) and at late luteal phase (LL) corresponding to the premenstrual phase. The following proinflammatory cytokines were determined at each sample: Interleukin 8 (IL-8), Interleukin 6 (IL-6), Interleukin 1α (IL-1α), and Tumor Necrosis Factor-α (TNF-α). Immediately before blood sampling the women completed the Zung self-rating depression scale and the hostility and direction of hostility questionnaire (HDHQ), which comprises five subscales: urge to act out hostility, criticism of others, paranoid hostility, self-criticism and delusional guilt. Spearman’s rank correlation was used to determine the relation between variables at the specific time points; ρ<0.05 was considered significant. Mean values of cytokines did not change significantly throughout the menstrual cycle. Paranoid hostility was positively correlated with IL-8 (Rs=0.476, p=0.046), IL-1α (Rs=0.458, p=0.048) and TNF-α (Rs=0.518, p=0.023) in LLphase. No other significant correlation was found. Cytokines correlate with paranoid hostility and this correlation is probably related with the premenstrual hormonal changes. It is difficult to evaluate the clinical significance of our findings, nevertheless, when exploring the above association, it is necessary to take into consideration the phase of the cycle as well as the special aspects of Ho we seek to study.","PeriodicalId":350784,"journal":{"name":"SOJ Neurology and Neuroscience","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126854258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0